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The biocomposites were obtained by varying the content of low deacetylated chitosan as matrix phase, mesoporous hydroxyapatite nano-powder, and potassium\u2013sodium niobate (K0.47Na0.53NbO3) sub-micron-sized powder. The resulting materials were characterized from physical, morpho-structural, and in vitro biological points of view. The porous scaffolds were obtained by freeze-drying the composite hydrogels and had a specific surface area of 18.4\u201424 m2\/g and a strong ability to retain fluid. Chitosan degradation was studied for 7 and 28 days of immersion in simulated body fluid without enzymatic presence. All synthesized compositions proved to be biocompatible in contact with osteoblast-like MG-63 cells and showed antibacterial effects. The best antibacterial effect was shown by the 10HA-90KNN-CSL hydrogel composition against Staphylococcus aureus and the fungal strain Candida albicans, while a weaker effect was observed for the dry scaffold.<\/jats:p>","DOI":"10.3390\/polym15112446","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T01:52:43Z","timestamp":1685065963000},"page":"2446","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Piezoelectric Biocomposites for Bone Grafting in Dentistry"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9317-9112","authenticated-orcid":false,"given":"Cristina Rodica","family":"Dumitrescu","sequence":"first","affiliation":[{"name":"Department of Impact of Build Environment and Nanomaterials, National Institute for Research and Development in Environmental Protection, 294 Splaiul Independen\u021bei Blv, 060031 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3197-6455","authenticated-orcid":false,"given":"Ionela Andreea","family":"Neacsu","sequence":"additional","affiliation":[{"name":"Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, University Politehnica of Bucharest, 060042 Bucharest, Romania"},{"name":"National Research Center for Micro and Nanomaterials, University Politehnica of Bucharest, 060042 Bucharest, Romania"},{"name":"Academy of Romanian Scientists, Splaiul Independentei Street No. 54, 011061 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Trusca","sequence":"additional","affiliation":[{"name":"National Research Center for Micro and Nanomaterials, University Politehnica of Bucharest, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana Cristina","family":"Popescu","sequence":"additional","affiliation":[{"name":"Department of Bioengineering and Biotechnology, Faculty of Medical Engineering, University Politehnica of Bucharest, 060042 Bucharest, Romania"},{"name":"Department of Life and Environmental Physics, National Institute for Research & Development \u201cHoria Hulubei\u201d, 30 Reactorului Street, 077125 Magurele, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iuliana","family":"Raut","sequence":"additional","affiliation":[{"name":"National Institute for Research & Development in Chemistry and Petrochemistry- ICECHIM, Splaiul Independentei Street No. 202, 060021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Constantin","sequence":"additional","affiliation":[{"name":"National Institute for Research & Development in Chemistry and Petrochemistry- ICECHIM, Splaiul Independentei Street No. 202, 060021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2226-5849","authenticated-orcid":false,"given":"Ecaterina","family":"Andronescu","sequence":"additional","affiliation":[{"name":"Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, University Politehnica of Bucharest, 060042 Bucharest, Romania"},{"name":"National Research Center for Micro and Nanomaterials, University Politehnica of Bucharest, 060042 Bucharest, Romania"},{"name":"Academy of Romanian Scientists, Splaiul Independentei Street No. 54, 011061 Bucharest, Romania"},{"name":"National Research Center for Food Safety, University Politehnica of Bucharest, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Iviglia, G., Kargozar, S., and Baino, F. 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