{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T15:13:20Z","timestamp":1782918800951,"version":"3.54.5"},"reference-count":59,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T00:00:00Z","timestamp":1697241600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"\u201cConsejer\u00eda de Econom\u00eda, Conocimiento, Empresas y Universidad\u201d, Andalusian Government (Spain)","award":["PR2022-017"],"award-info":[{"award-number":["PR2022-017"]}]},{"name":"\u201cConsejer\u00eda de Econom\u00eda, Conocimiento, Empresas y Universidad\u201d, Andalusian Government (Spain)","award":["INBIO 2022"],"award-info":[{"award-number":["INBIO 2022"]}]},{"name":"\u201cConsejer\u00eda de Econom\u00eda, Conocimiento, Empresas y Universidad\u201d, Andalusian Government (Spain)","award":["SC2022-002"],"award-info":[{"award-number":["SC2022-002"]}]},{"name":"University of Cadiz (Spain)","award":["PR2022-017"],"award-info":[{"award-number":["PR2022-017"]}]},{"name":"University of Cadiz (Spain)","award":["INBIO 2022"],"award-info":[{"award-number":["INBIO 2022"]}]},{"name":"University of Cadiz (Spain)","award":["SC2022-002"],"award-info":[{"award-number":["SC2022-002"]}]},{"name":"Central Research Service for Science and Technology from the University of Cadiz (Spain)","award":["PR2022-017"],"award-info":[{"award-number":["PR2022-017"]}]},{"name":"Central Research Service for Science and Technology from the University of Cadiz (Spain)","award":["INBIO 2022"],"award-info":[{"award-number":["INBIO 2022"]}]},{"name":"Central Research Service for Science and Technology from the University of Cadiz (Spain)","award":["SC2022-002"],"award-info":[{"award-number":["SC2022-002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>The design, characterization, and analytical application of a green optical sensor for the selective determination of Fe(II) ions is proposed. The sensor is based on the immobilization of the chromogenic reagent picolinaldehyde salicyloylhydrazone (SHPA) within a polymer inclusion membrane. To reduce solvent usage, the reagent was synthesized using a green mechanochemical procedure. The components for sensor preparation were optimized with a sequential simplex method and the optimal composition was found to be 0.59 g cellulose triacetate (base polymer), 0.04 g SHPA (chemosensor reagent), 4.9 mL dibutyl phthalate (plasticizer), and 38 mL dichloromethane (solvent). The conditions of iron analysis were also optimized resulting in pH 6 for aqueous solution, 90 min exposure time and 10 min short-term stability. The optical sensor showed a linear range from the limit of detection (0.48 \u00b5mol L\u22121) to 54 \u00b5mol L\u22121 Fe(II). The precision of the method was found to be 1.44% and 1.19% for 17.9 and 45 \u00b5mol L\u22121 Fe(II), respectively. The characteristics of the sensor allowed the design of a Fe(II)\/Fe(III) speciation scheme. The methodology was successfully applied to the determination of iron in food preservatives, food additives, and dietary supplement. Additionally, the Fe speciation scheme was successfully applied to an agricultural fertilizer.<\/jats:p>","DOI":"10.3390\/polym15204082","type":"journal-article","created":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T14:59:59Z","timestamp":1697295599000},"page":"4082","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Novel Polymer Inclusion Membrane-Based Green Optical Sensor for Selective Determination of Iron: Design, Characterization, and Analytical Applications"],"prefix":"10.3390","volume":"15","author":[{"given":"Lorena","family":"S\u00e1nchez-Ponce","sequence":"first","affiliation":[{"name":"Department of Analytical Chemistry, Institute of Biomolecules (INBIO), Faculty of Sciences, International Campus of Excellence of the Sea (CEI-MAR), University of Cadiz, Campus Rio San Pedro, Puerto Real, 11510 Cadiz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Casanueva-Marenco","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Institute of Biomolecules (INBIO), Faculty of Sciences, International Campus of Excellence of the Sea (CEI-MAR), University of Cadiz, Campus Rio San Pedro, Puerto Real, 11510 Cadiz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8300-3922","authenticated-orcid":false,"given":"Margarita","family":"D\u00edaz-de-Alba","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Institute of Biomolecules (INBIO), Faculty of Sciences, International Campus of Excellence of the Sea (CEI-MAR), University of Cadiz, Campus Rio San Pedro, Puerto Real, 11510 Cadiz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3306-0539","authenticated-orcid":false,"given":"Mar\u00eda Dolores","family":"Galindo-Ria\u00f1o","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Institute of Biomolecules (INBIO), Faculty of Sciences, International Campus of Excellence of the Sea (CEI-MAR), University of Cadiz, Campus Rio San Pedro, Puerto Real, 11510 Cadiz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9902-7224","authenticated-orcid":false,"given":"Mar\u00eda Dolores","family":"Granado-Castro","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Institute of Biomolecules (INBIO), Faculty of Sciences, International Campus of Excellence of the Sea (CEI-MAR), University of Cadiz, Campus Rio San Pedro, Puerto Real, 11510 Cadiz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"10369","DOI":"10.1039\/c2cc34706g","article-title":"Chemical and biological sensors based on metal oxide nanostructures","volume":"48","author":"Hahn","year":"2012","journal-title":"Chem. 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