{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:04:03Z","timestamp":1792523043552,"version":"4.5.0"},"reference-count":143,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52473014"],"award-info":[{"award-number":["52473014"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Antifouling coatings stand out as one of the highly efficient ways to mitigate surface contamination. Traditional antifouling coatings have a major drawback: they rely on highly toxic and environmentally hazardous compounds. These substances not only lead to ecological harm but also disrupt the natural equilibrium of ecosystems. Consequently, in recent years, eco-friendly antifouling bio-coatings have emerged. This review focuses on the mechanisms and processes underlying contaminant adhesion, laying a solid foundation for grasping the principles of antifouling coating design. It further elaborates on the general strategies for developing bio-based antifouling solutions, highlighting their potential across a wide array of applications. Finally, this review carefully analyzes the current challenges confronted by antifouling bio-coatings and puts forward future development directions. Through a comprehensive overview, we aim to expand the influence of bio-based antifouling technologies, promote the further application of bio-based antifouling coatings in marine antifouling and medical antifouling fields, and provide examples for the establishment of environmental protection policies.<\/jats:p>","DOI":"10.3390\/polym17060793","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T11:04:22Z","timestamp":1742209462000},"page":"793","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Design and Application of Antifouling Bio-Coatings"],"prefix":"10.3390","volume":"17","author":[{"given":"Jinglin","family":"Wang","sequence":"first","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi\u2019an 710119, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi\u2019an 710119, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yage","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi\u2019an 710119, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9212-8439","authenticated-orcid":false,"given":"Yongchun","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi\u2019an 710119, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1002\/adma.201001215","article-title":"Antifouling Coatings: Recent Developments in the Design of Surfaces That Prevent Fouling by Proteins, Bacteria, and Marine Organisms","volume":"23","author":"Banerjee","year":"2011","journal-title":"Adv. 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