{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:57:49Z","timestamp":1787317069161,"version":"build-2736575974"},"reference-count":119,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>This work is devoted to the electrospinning of biocompatible fibrous matrixes for microbial wound therapy. The problem of treating staphylococcal-infected wounds remains urgent. In this study, we propose a new approach to the use of the chlorophyll (Chl) and poly-3-hydroxybutyrate (PHB) composite system in the treatment of infected wounds. The structure and properties of the electrospun polymer matrix based on PHB modified with various concentrations of Chl was investigated by SEM, confocal microscopy, DSC, EPR. The release rate, fluorescence, and antimicrobial activity of Chl incorporated into PHB were studied. The high efficiency of the developed materials was shown with the participation of laboratory animals.<\/jats:p>","DOI":"10.3390\/polym17182507","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T11:00:00Z","timestamp":1758106800000},"page":"2507","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Antimicrobial Evaluation of Chlorophyll-Containing Nettle Extract Both in Free Form and Incorporated into Poly-3-Hydroxybutyrate"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4217-2022","authenticated-orcid":false,"given":"Polina M.","family":"Tyubaeva","sequence":"first","affiliation":[{"name":"Department of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina St., 119334 Moscow, Russia"},{"name":"Academic Department of Innovational Materials and Technologies Chemistry, Plekhanov Russian University of Economics, 36 Stremyanny Per., 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivetta A.","family":"Varyan","sequence":"additional","affiliation":[{"name":"Department of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina St., 119334 Moscow, Russia"},{"name":"Academic Department of Innovational Materials and Technologies Chemistry, Plekhanov Russian University of Economics, 36 Stremyanny Per., 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2930-8768","authenticated-orcid":false,"given":"Sergei I.","family":"Obydennyi","sequence":"additional","affiliation":[{"name":"Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia"},{"name":"Centre for Theoretical Problems of Physicochemical Pharmacology, 119334 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasily A.","family":"Merzlikin","sequence":"additional","affiliation":[{"name":"Department of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina St., 119334 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana G.","family":"Karpova","sequence":"additional","affiliation":[{"name":"Department of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina St., 119334 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga A.","family":"Gruznova","sequence":"additional","affiliation":[{"name":"Laboratory of Liquid-Phase Oxidation, N.N. 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Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences\u201d, 5 Zvenigorodskoye Highway, 123022 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolay N.","family":"Kuvshinchikov","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Sanitation, All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology\u2014Branch of Federal State Budget Scientific Institution \u201cFederal Scientific Center\u2014K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences\u201d, 5 Zvenigorodskoye Highway, 123022 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolay I.","family":"Popov","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Sanitation, All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology\u2014Branch of Federal State Budget Scientific Institution \u201cFederal Scientific Center\u2014K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences\u201d, 5 Zvenigorodskoye Highway, 123022 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton V.","family":"Lobanov","sequence":"additional","affiliation":[{"name":"Department of General Chemistry, Moscow Pedagogical State University, 1\/1 Malaya Pirogovskaya Street, 119435 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7433-7728","authenticated-orcid":false,"given":"Ivan A.","family":"Abramov","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology and Parasitology, Centre for Strategic Planning and Management of Biomedical Health Risks of Federal Medical Biological Agency, Pogodinskaya Str., 10\/1, 119121 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrey P.","family":"Sergeev","sequence":"additional","affiliation":[{"name":"Department of Systems Biology and Bioinformatics, Centre for Strategic Planning and Management of Biomedical Health Risks of Federal Medical Biological Agency, Pogodinskaya Str., 10\/1, 119121 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anzhelika V.","family":"Zagaynova","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology and Parasitology, Centre for Strategic Planning and Management of Biomedical Health Risks of Federal Medical Biological Agency, Pogodinskaya Str., 10\/1, 119121 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0615-6914","authenticated-orcid":false,"given":"Anatoly A.","family":"Olkhov","sequence":"additional","affiliation":[{"name":"Department of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina St., 119334 Moscow, Russia"},{"name":"Academic Department of Innovational Materials and Technologies Chemistry, Plekhanov Russian University of Economics, 36 Stremyanny Per., 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nature17042","article-title":"Antibacterial Drug Discovery in the Resistance Era","volume":"529","author":"Brown","year":"2016","journal-title":"Nature"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"119603","DOI":"10.1016\/j.envpol.2022.119603","article-title":"Role of Environmental Stresses in Elevating Resistance Mutations in Bacteria: Phenomena and Mechanisms","volume":"307","author":"Wang","year":"2022","journal-title":"Environ. 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