{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:15:45Z","timestamp":1783462545573,"version":"3.55.0"},"reference-count":45,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:00:00Z","timestamp":1761609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004951","name":"Ataturk University Scientific Research Coordinators","doi-asserted-by":"publisher","award":["TAB-2021-9807"],"award-info":[{"award-number":["TAB-2021-9807"]}],"id":[{"id":"10.13039\/501100004951","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Denture hygiene is crucial for preventing oral infections, with Candida albicans being a common fungal pathogen that can colonize denture surfaces. This in vitro study evaluated the adherence of C. albicans on two denture base materials\u2014polyamide and polymethyl methacrylate (PMMA)\u2014and assessed the antifungal efficacy of various chemical and natural cleansers. A total of 100 polished specimens were inoculated with C. albicans and treated with chemical agents (Listerine at 2%, 20%, 50%; Corega\u00ae, Block Drug Company, Jersey City, NJ, USA); Protefix\u00ae, Queisser Pharma, Flensburg, Germany and natural products (15% apple vinegar, 2% tea tree oil, 2% peppermint oil) for different durations (5, 15, 30, 480 min). Chlorhexidine (2%) and untreated samples served as positive and negative controls, respectively. Corega\u00ae and 15% vinegar eliminated C. albicans within 5 min on both materials. 50% Listerine was effective after 5 min on PMMA but required 480 min on polyamide. Protefix\u00ae showed full efficacy in 5 min on PMMA and 30 min on polyamide. Tea tree oil required 30\u2013480 min for activity, while peppermint oil showed minimal effect throughout. Under the tested conditions, Corega\u00ae appeared most effective. Natural cleansers, particularly vinegar and tea tree oil, also showed considerable anticandidal potential, suggesting they may serve as alternative agents for denture hygiene applications.<\/jats:p>","DOI":"10.3390\/polym17212869","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:59:36Z","timestamp":1761659976000},"page":"2869","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["In Vitro Evaluation of Plant Antimicrobials Against Candida albicans Biofilm on Denture Base Materials: A Comparison with Chemical Denture Cleansers"],"prefix":"10.3390","volume":"17","author":[{"given":"Nurdan","family":"Polat Sagsoz","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, Faculty of Dentistry, Atat\u00fcrk University, 25240 Erzurum, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Figen","family":"Orhan","sequence":"additional","affiliation":[{"name":"Vocational College of Health Services, Atat\u00fcrk University, 25240 Erzurum, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2679-5599","authenticated-orcid":false,"given":"Ozlem","family":"Baris","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Science, Atat\u00fcrk University, 25240 Erzurum, T\u00fcrkiye"},{"name":"Department of Biology, Science Faculty, Kyrgyz-Turkish Manas University, 720038 Bishkek, Kyrgyzstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer","family":"Sagsoz","sequence":"additional","affiliation":[{"name":"Department of Restorative Treatment, Faculty of Dentistry, Atat\u00fcrk University, 25240 Erzurum, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"525","DOI":"10.5505\/TurkHijyen.2021.87864","article-title":"Evaluation of in vitro antimicrobial effect of different essential oils","volume":"78","author":"Aslan","year":"2021","journal-title":"Turk. 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