{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T14:36:02Z","timestamp":1776695762448,"version":"3.51.2"},"reference-count":44,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Convocatoria de Ciencia B\u00e1sica y de Frontera 2025 of SECIHTI","award":["CBF-2025-I-1532"],"award-info":[{"award-number":["CBF-2025-I-1532"]}]},{"name":"Secretar\u00eda de Investigaci\u00f3n y Posgrado: Convocatoria de apoyos econ\u00f3micos para publicaciones y tr\u00e1mite de invenciones from the Instituto Polit\u00e9cnico Nacional"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Massive pelagic Sargassum influxes along Caribbean coasts have created an urgent need for valorization routes for this biomass. Here, sodium alginate was extracted from Sargassum fluitans collected at Chuburn\u00e1 Beach, Yucat\u00e1n, Mexico, using a multistep extraction involving 0.2% formaldehyde pretreatment at 4 \u00b0C and brief heating at 65\u201370 \u00b0C, and subsequently used to prepare calcium-crosslinked alginate nanoparticles by ionotropic gelation. To our knowledge, this is the first direct synthesis of alginate nanoparticles from non-commercial alginate extracted from pelagic S. fluitans. An extraction yield of 18.7 \u00b1 0.05% (mean \u00b1 SD, n = 3) was obtained, and UV\u2013Vis, FTIR, and NMR analyses confirmed the characteristic structural features of alginate. 1H NMR revealed an M-rich composition (F_M = 0.61, F_G = 0.39; M\/G = 1.54) with short guluronate blocks (N_G&gt;1 = 2.42), whereas 13C NMR corroborated the presence of both \u03b2-D-mannuronic and \u03b1-L-guluronic acid residues. SEM images showed predominantly spherical-to-subspherical nanoparticles with representative dry diameters of 233\u2013269 nm, whereas DLS measurements at 0, 24, and 72 h revealed a dominant volume-based nanoscale population with main peaks at 12.75\u201315.31 nm and PDI values of 0.229\u20130.291, indicating reasonable short-term colloidal stability at room temperature. These results demonstrate that pelagic S. fluitans can serve as a viable feedstock for the production of structurally preserved alginate and calcium-crosslinked alginate nanoparticles. The study supports converting recurrent Sargassum biomass into higher-value polysaccharide-based materials and provides a basis for future application-specific evaluation of these nanomaterials.<\/jats:p>","DOI":"10.3390\/polym18080996","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:22:47Z","timestamp":1776691367000},"page":"996","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Honey-Stabilized Alginate Nanoparticles Derived from Sargassum: Synthesis, Physicochemical Characterization and Colloidal Stability"],"prefix":"10.3390","volume":"18","author":[{"given":"Hannia A.","family":"Ram\u00edrez-Lara","sequence":"first","affiliation":[{"name":"Centro de Investigaci\u00f3n en Ciencia Aplicada y Tecnolog\u00eda Avanzada (CICATA) Unidad Morelos del Instituto Polit\u00e9cnico Nacional (IPN), Xochitepec C.P. 62790, Morelos, Mexico"},{"name":"Tecnol\u00f3gico Nacional de M\u00e9xico, Instituto Tecnol\u00f3gico (IT) de Zacatepec, Calzada Tecnol\u00f3gico 27, Centro, Zacatepec C.P. 62780, Morelos, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley J.","family":"Gutierrez-Onofre","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Ciencia Aplicada y Tecnolog\u00eda Avanzada (CICATA) Unidad Morelos del Instituto Polit\u00e9cnico Nacional (IPN), Xochitepec C.P. 62790, Morelos, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0313-6283","authenticated-orcid":false,"given":"Ren\u00e9","family":"Salgado-Delgado","sequence":"additional","affiliation":[{"name":"Tecnol\u00f3gico Nacional de M\u00e9xico, Instituto Tecnol\u00f3gico (IT) de Zacatepec, Calzada Tecnol\u00f3gico 27, Centro, Zacatepec C.P. 62780, Morelos, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Areli Marl\u00e9n","family":"Salgado-Delgado","sequence":"additional","affiliation":[{"name":"Tecnol\u00f3gico Nacional de M\u00e9xico, Instituto Tecnol\u00f3gico (IT) de Zacatepec, Calzada Tecnol\u00f3gico 27, Centro, Zacatepec C.P. 62780, Morelos, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0488-7900","authenticated-orcid":false,"given":"Iliana C.","family":"Mart\u00ednez-Ort\u00edz","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Ciencia Aplicada y Tecnolog\u00eda Avanzada (CICATA) Unidad Morelos del Instituto Polit\u00e9cnico Nacional (IPN), Xochitepec C.P. 62790, Morelos, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nahomi Y.","family":"Degollado-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Ciencia Aplicada y Tecnolog\u00eda Avanzada (CICATA) Unidad Morelos del Instituto Polit\u00e9cnico Nacional (IPN), Xochitepec C.P. 62790, Morelos, Mexico"},{"name":"Divisi\u00f3n Acad\u00e9mica de Mec\u00e1nica Industrial, Universidad Tecnol\u00f3gica Emiliano Zapata del Estado de Morelos, Av. Universidad Tecnol\u00f3gica 1, Palo Escrito, Emiliano Zapata C.P. 62765, Morelos, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1551-2685","authenticated-orcid":false,"given":"Igor","family":"Garcia-Atutxa","sequence":"additional","affiliation":[{"name":"Escuela Polit\u00e9cnica Superior, Universidad Cat\u00f3lica de Murcia (UCAM), Av. de los Jer\u00f3nimos, C.P. 30107 Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisca","family":"Villanueva-Flores","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Ciencia Aplicada y Tecnolog\u00eda Avanzada (CICATA) Unidad Morelos del Instituto Polit\u00e9cnico Nacional (IPN), Xochitepec C.P. 62790, Morelos, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"106216","DOI":"10.1016\/j.marenvres.2023.106216","article-title":"Seaweed and climate change: A mapping review","volume":"192","author":"Segaran","year":"2023","journal-title":"Mar. 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