{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:15:58Z","timestamp":1790392558539,"version":"4.1.0"},"reference-count":63,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>The present work aimed to obtain antibacterial wound dressings using bacterial cellulose (BC) as a support, to improve wound treatment and reduce the incidence of infections. To enhance the antibacterial activity of the synthesized dressings, the introduction of ZnO nanoparticles into the BC network by precipitation was pursued. The method chosen to develop ZnO NPs was green synthesis, an ecological and sustainable method for obtaining nanomaterials using plant extracts as reducing agents or stabilizers. Thus, the chosen plants were Ginger rhizomes, Bay leaves, and Rose hips, in both fresh and dry form, due to the natural benefits they possess, and the Soxhlet method was used to obtain the plant extracts desired to be used in the synthesis. The composite dressings were developed in two distinct sample series, differentiated by the immersion time of BC in the precursor Zn2+ solution. The samples in the first series were obtained by precipitation in a mixture of Zn2+ solution and natural extract, whereas the samples in the second series were obtained by successive immersion in Zn2+ solution and then in natural extract, which demonstrated a considerable difference. The best antimicrobial activity tested against Gram-negative bacterium Escherichia coli was recorded for the composite material obtained in the presence of fresh rose hip extract, an aspect most likely related to the morphological and crystalline features of the ZnO phase, but also to the phytochemical profile of the extract used. Such eco-friendly materials represent valuable candidates for wound dressing applications due to their ability to support wound healing, relief burns, and skin irritation, provide antimicrobial protection, promote skin regeneration and reduce scarring, protect sensitive skin, and act as a barrier against external contaminants.<\/jats:p>","DOI":"10.3390\/polym18091050","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T19:24:51Z","timestamp":1777317891000},"page":"1050","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Green-Synthesized Zinc Oxide\u2013Bacterial Cellulose Composites: Eco-Friendly Antibacterial Wound Dressings for Faster Healing"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0597-0789","authenticated-orcid":false,"given":"Iuliana-Mihaela","family":"Deleanu","sequence":"first","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, RO-060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorana-Gabriela","family":"Ivanescu","sequence":"additional","affiliation":[{"name":"Faculty of Medical Engineering, National University of Science and Technology Politehnica Bucharest, RO-060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0763-540X","authenticated-orcid":false,"given":"Gabriela-Olimpia","family":"Isopencu","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, RO-060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8145-1094","authenticated-orcid":false,"given":"Ovidiu-Cristian","family":"Oprea","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, RO-060042 Bucharest, Romania"},{"name":"National Center of Micro and Nanomaterials, National University of Science and Technology Politehnica Bucharest, RO-060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7309-6002","authenticated-orcid":false,"given":"Mihaela","family":"Bacalum","sequence":"additional","affiliation":[{"name":"Horia Hulubei National Institute of Physics and Nuclear Engineering, RO-077125 Magurele, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana-Lavinia","family":"Stan","sequence":"additional","affiliation":[{"name":"Horia Hulubei National Institute of Physics and Nuclear Engineering, RO-077125 Magurele, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorin-Ion","family":"Jinga","sequence":"additional","affiliation":[{"name":"Faculty of Medical Engineering, National University of Science and Technology Politehnica Bucharest, RO-060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0392-8459","authenticated-orcid":false,"given":"Cristina","family":"Busuioc","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, RO-060042 Bucharest, Romania"},{"name":"National Center of Micro and Nanomaterials, National University of Science and Technology Politehnica Bucharest, RO-060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,26]]},"reference":[{"key":"ref_1","first-page":"550024","article-title":"Green Synthesis of ZnO Nanoparticles: A Sustainable Approach for Wound Care","volume":"19","year":"2026","journal-title":"Nanotechnol. Sci. Appl."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Okaiyeto, K., Gigliobianco, M.R., and Di Martino, P. (2024). Biogenic Zinc Oxide Nanoparticles as a Promising Antibacterial Agent: Synthesis and Characterization. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms25179500"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00449-024-03123-z","article-title":"Green Synthesized ZnO and ZnO-Based Composites for Wound Healing Applications","volume":"48","author":"Wafi","year":"2025","journal-title":"Bioprocess Biosyst. Eng."},{"key":"ref_4","unstructured":"(2026, March 31). 21 CFR 182.8991\u2014Zinc Oxide, Available online: https:\/\/www.ecfr.gov\/current\/title-21\/part-182\/section-182.8991."},{"key":"ref_5","first-page":"1","article-title":"Green Synthesis of Zinc Oxide Nanoparticles and Their Application in Anticancer Drug Delivery\u2014A Review","volume":"21","author":"Stolarczyk","year":"2026","journal-title":"Int. J. Nanomed."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1049\/iet-nbt.2015.0031","article-title":"In Situ Detection of the Zn2+ Release Process of ZnO NPs in Tumour Cells by Confocal Laser Scanning Fluorescence Microscopy","volume":"10","author":"Song","year":"2016","journal-title":"IET Nanobiotechnol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"102221","DOI":"10.1016\/j.mtbio.2025.102221","article-title":"Zinc Oxide Nanoparticles for Skin Wound Healing: A Systematic Review from the Perspective of Disease Types","volume":"34","author":"Xiao","year":"2025","journal-title":"Mater. Today Bio"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"20992","DOI":"10.1039\/D4RA02452D","article-title":"Cutting-Edge Developments in Zinc Oxide Nanoparticles: Synthesis and Applications for Enhanced Antimicrobial and UV Protection in Healthcare Solutions","volume":"14","author":"Irede","year":"2024","journal-title":"RSC Adv."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1007\/s10904-023-02550-x","article-title":"Biogenic Zinc Oxide Nanoparticles and Their Biomedical Applications: A Review","volume":"33","author":"Jha","year":"2023","journal-title":"J. Inorg. Organomet. Polym. Mater."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s43994-023-00076-z","article-title":"Biogenic Synthesis of ZnO Nanoparticles from Evolvulus Alsinoides Plant Extract","volume":"10","author":"Yadav","year":"2024","journal-title":"J. Umm Al-Qura Univ. Appl. Sci."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"103028","DOI":"10.1016\/j.rechem.2026.103028","article-title":"Green Synthesis of Zinc Oxide Nanoparticles: Advances, Applications, and AI-Driven Innovations for Sustainability","volume":"20","author":"Gong","year":"2026","journal-title":"Results Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"113820","DOI":"10.1016\/j.matdes.2025.113820","article-title":"Preparation of Bacterial Cellulose-Based Antimicrobial Materials and Their Applications in Wound Dressing: A Review","volume":"253","author":"Dang","year":"2025","journal-title":"Mater. Des."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e00072","DOI":"10.1002\/adtp.202500072","article-title":"Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings","volume":"8","author":"Sener","year":"2025","journal-title":"Adv. Ther."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2419806","DOI":"10.1080\/20565623.2024.2419806","article-title":"Green Synthesized Zingiber officinale-ZnO Nanoparticles: Anticancer Efficacy against 3D Breast Cancer Model","volume":"10","author":"Alhaddad","year":"2024","journal-title":"Future Sci. OA"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Alqahtani, O.S., Muddapur, U.M., Kamat, K., Shenvi, A., Shaikh, I.A., Aljaezi, I., Al Kazman, B.S.M., Alshamrani, M.A., Khan, A.A., and Al-Qahtani, A.M. (2025). Sustainable Green Synthesis of Zinc Oxide Nanoparticles Utilizing Zingiber officinale Peel Aqueous Extract, Characterization, and Determination of Its Anticancer and Antimicrobial Potential. PLoS ONE, 20.","DOI":"10.1371\/journal.pone.0334685"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"118240","DOI":"10.1016\/j.mseb.2025.118240","article-title":"Green Synthesis of Zinc Oxide Nanoparticles via Zingiber officinale\/PEG Biopolymer Blend Matrix: Optimization, Physicochemical Characterization, Antioxidant and Photocatalytic Activity","volume":"317","author":"Dilber","year":"2025","journal-title":"Mater. Sci. Eng. B"},{"key":"ref_17","first-page":"7036247","article-title":"Green Synthesis Method of ZnO Nanoparticles Using Extracts of Zingiber officinale and Garlic Bulb (Allium sativum) and Their Synergetic Effect for Antibacterial Activities","volume":"2023","year":"2023","journal-title":"J. Nanomater."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"285","DOI":"10.21608\/ejmm.2025.351880.1435","article-title":"Sustainable and Green Zinc Oxide Nanoparticle Synthesis from Zingiber officinale as a Wound Healing Accelerator","volume":"34","author":"Najim","year":"2025","journal-title":"Egypt. J. Med. Microbiol."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Tabe, M.B., Isbilen, O., Walker, J.N., and Cinar, E. (2026). Zingiber officinale-Mediated Zinc Oxide Nanoparticles: Antimicrobial Activity against Multidrug-Resistant Bacteria. BMC Complement. Med. Ther., 26.","DOI":"10.1186\/s12906-026-05281-x"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1007\/s13738-024-02981-4","article-title":"Green Synthesis of ZnO Nanoparticles Using Laurus nobilis L. Extract and Investigation of Corrosion Inhibition Properties of DES-Based Nanofluids","volume":"21","author":"Dalmaz","year":"2024","journal-title":"J. Iran. Chem. Soc."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/17518253.2018.1547925","article-title":"Green Synthesis of Zinc Oxide Nanoparticles: A Comparison","volume":"12","author":"Fakhari","year":"2019","journal-title":"Green Chem. Lett. Rev."},{"key":"ref_22","first-page":"100138","article-title":"Laurus Nobilis-Mediated Fabrication of Multifunctional ZrO2\u2013ZnO Nanostructures for Wastewater Remediation and Biocidal Applications","volume":"8","author":"Garud","year":"2026","journal-title":"Chem. Inorg. Mater."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s12298-024-01508-8","article-title":"Green Synthesis and Characterization of Fe2O3, ZnO and TiO2 Nanoparticles and Searching for Their Potential Use as Biofertilizer on Sunflower","volume":"30","author":"Aydin","year":"2024","journal-title":"Physiol. Mol. Biol. Plants"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1016\/j.biopha.2016.10.038","article-title":"Laurus Nobilis Leaf Extract Mediated Green Synthesis of ZnO Nanoparticles: Characterization and Biomedical Applications","volume":"84","author":"Vijayakumar","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e202402724","DOI":"10.1002\/cbdv.202402724","article-title":"Green Synthesis of Zinc Oxide Nanoparticles Including Rosehip (Rosa canina L.) Seed Extract: Evaluation of Its Characterization and Bioactivity Properties","volume":"22","author":"Bozkurt","year":"2025","journal-title":"Chem. Biodivers."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.msec.2015.09.089","article-title":"Biofabrication of Zinc Oxide Nanoparticles Using Fruit Extract of Rosa canina and Their Toxic Potential against Bacteria: A Mechanistic Approach","volume":"59","author":"Jafarirad","year":"2016","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Busuioc, C., Isopencu, G., Banciu, A., Banciu, D.-D., Oprea, O., Mocanu, A., Deleanu, I., Z\u0103ule\u0163, M., Popescu, L., and T\u0103n\u0103suic\u0103, R. (2022). Bacterial Cellulose Hybrid Composites with Calcium Phosphate for Bone Tissue Regeneration. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms232416180"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Dogaru, A.-I., Oprea, O.-C., Isopencu, G.-O., Banciu, A., Jinga, S.-I., and Busuioc, C. (2025). Bacterial Cellulose-Based Nanocomposites for Wound Healing Applications. Polymers, 17.","DOI":"10.3390\/polym17091225"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"26616","DOI":"10.1038\/s41598-024-77305-w","article-title":"Exploring the Acetobacteraceae Family Isolated from Kombucha SCOBYs Worldwide and Comparing Yield and Characteristics of Biocellulose under Various Fermentation Conditions","volume":"14","author":"Khiabani","year":"2024","journal-title":"Sci. Rep."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1007\/s11756-022-01222-4","article-title":"Komagataeibacter Saccharivorans Strain BC-G1: An Alternative Strain for Production of Bacterial Cellulose","volume":"77","author":"Srivastava","year":"2022","journal-title":"Biologia"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Cao, S., Liang, J., Chen, M., Xu, C., Wang, X., Qiu, L., Zhao, X., and Hu, W. (2025). Comparative Analysis of Extraction Technologies for Plant Extracts and Absolutes. Front. Chem., 13.","DOI":"10.3389\/fchem.2025.1536590"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"14","DOI":"10.26599\/NBE.2023.9290003","article-title":"Antimicrobial Activity of ZnO Nanoparticles Prepared Using a Green Synthesis Approach","volume":"15","author":"Ghdeeb","year":"2023","journal-title":"Nano Biomed. Eng."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1038\/s41598-024-52455-z","article-title":"The Physical Properties and Photocatalytic Activities of Green Synthesized ZnO Nanostructures Using Different Ginger Extract Concentrations","volume":"14","author":"Aliannezhadi","year":"2024","journal-title":"Sci. Rep."},{"key":"ref_34","first-page":"15589250211046242","article-title":"A Review of the Green Synthesis of ZnO Nanoparticles Using Plant Extracts and Their Prospects for Application in Antibacterial Textiles","volume":"16","author":"Xu","year":"2021","journal-title":"J. Eng. Fibers Fabr."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Karnwal, A., Jassim, A.Y., Mohammed, A.A., Sharma, V., Al-Tawaha, A.R.M.S., and Sivanesan, I. (2024). Nanotechnology for Healthcare: Plant-Derived Nanoparticles in Disease Treatment and Regenerative Medicine. Pharmaceuticals, 17.","DOI":"10.3390\/ph17121711"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Bourqui, A., Csajka, C., Heinrich, M., Podmore, C., Simpson, C., Trill, J., Willcox, M., and Rodondi, P.-Y. (2026). Challenges in Performing Clinical Research on Herbal Products\u2014Experiences from Switzerland and the UK. Front. Pharmacol., 17.","DOI":"10.3389\/fphar.2026.1766381"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Panchal, P., Rauwel, P., Nehra, S.P., Singh, P., Karla, M., Hermosa, G., and Rauwel, E. (2025). A Review on Biomedical Applications of Plant Extract-Mediated Metallic Ag, Au, and ZnO Nanoparticles and Future Prospects for Their Combination with Graphitic Carbon Nitride. Pharmaceuticals, 18.","DOI":"10.3390\/ph18060820"},{"key":"ref_38","first-page":"71","article-title":"Standardization and Phytochemical Profiling of Medicinal Plant Extracts: Approaches and Advances","volume":"3","author":"Gaikwad","year":"2025","journal-title":"J. Adv. Ayurveda Yoga Homeopath. Naturop."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"100312","DOI":"10.1016\/j.nxnano.2025.100312","article-title":"A Critical Review on the Fabrication of ZnO Nanoparticles and Their Antidiabetic and Anticancer Activities","volume":"8","author":"SenthilKumar","year":"2025","journal-title":"Next Nanotechnol."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Villagr\u00e1n, Z., Anaya-Esparza, L.M., Vel\u00e1zquez-Carriles, C.A., Silva-Jara, J.M., Ruvalcaba-G\u00f3mez, J.M., Aurora-Vigo, E.F., Rodr\u00edguez-Lafitte, E., Rodr\u00edguez-Barajas, N., Balderas-Le\u00f3n, I., and Mart\u00ednez-Esquivias, F. (2024). Plant-Based Extracts as Reducing, Capping, and Stabilizing Agents for the Green Synthesis of Inorganic Nanoparticles. Resources, 13.","DOI":"10.3390\/resources13060070"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s44509-026-00006-2","article-title":"A Comprehensive Review of Green Synthesis Methods and Applications of Nanoparticles Derived from Plant Extracts and Microorganisms","volume":"1","author":"Syed","year":"2026","journal-title":"Discov. Green Chem."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s10971-025-07067-y","article-title":"Harnessing Plant Extracts for Zinc Oxide Nanoparticles: A Greener Route to Enhanced Biocompatibility and Therapeutic Potential","volume":"117","author":"Said","year":"2026","journal-title":"J. Sol-Gel Sci. Technol."},{"key":"ref_43","first-page":"101195","article-title":"Harnessing Plant Extracts for Green Nanoparticle Synthesis: Toward a Sustainable Future","volume":"31","author":"Khan","year":"2025","journal-title":"Mater. Today Sustain."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"4885","DOI":"10.1039\/D4NA00326H","article-title":"Biosynthesis of ZnO Nanoparticles Using Aqueous Extracts of Eclipta prostrata and Piper longum: Characterization and Assessment of Their Antioxidant, Antibacterial, and Photocatalytic Properties","volume":"6","author":"Tran","year":"2024","journal-title":"Nanoscale Adv."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Mutukwa, D., Taziwa, R.T., and Khotseng, L. (2024). A Review of Plant-Mediated ZnO Nanoparticles for Photodegradation and Antibacterial Applications. Nanomaterials, 14.","DOI":"10.3390\/nano14141182"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"101724","DOI":"10.1016\/j.rechem.2024.101724","article-title":"Facile Biosynthesis of Zinc Oxide Nanoparticles (ZnO NPs) Using Lupinus albus L (Gibto) Seed Extract for Antibacterial and Photocatalytic Applications","volume":"10","year":"2024","journal-title":"Results Chem."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"46890","DOI":"10.1039\/D5RA05878C","article-title":"Sustainable Production of ZnO Nanoparticles via Capparis decidua Stem Extract for Efficient Photocatalytic Rh 6G Dye Degradation","volume":"15","author":"Sayed","year":"2025","journal-title":"RSC Adv."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"130391","DOI":"10.1016\/j.ijbiomac.2024.130391","article-title":"Physicochemical and Photocatalytic Properties of Biogenic ZnO and Its Chitosan Nanocomposites for UV-Protection and Antibacterial Activity on Coated Textiles","volume":"263","author":"Subramani","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_49","first-page":"3411","article-title":"Germination and Growth Characteristics of Mungbean Seeds (Vigna radiata L.) Affected by Synthesized Zinc Oxide Nanoparticles","volume":"4","author":"Jayarambabu","year":"2014","journal-title":"Int. J. Curr. Eng. Technol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1515\/msp-2018-0041","article-title":"Optical Investigations of Microwave Induced Synthesis of Zinc Oxide Thin-Film","volume":"36","author":"Ansari","year":"2018","journal-title":"Mater. Sci.-Pol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"6024","DOI":"10.1039\/c1ce05502j","article-title":"From Zn(OH)2 to ZnO: A Study on the Mechanism of Phase Transformation","volume":"13","author":"Wang","year":"2011","journal-title":"CrystEngComm"},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"De Oliveira Barud, H.G., Da Silva, R.R., Borges, M.A.C., Castro, G.R., Ribeiro, S.J.L., and Da Silva Barud, H. (2020). Bacterial Nanocellulose in Dentistry: Perspectives and Challenges. Molecules, 26.","DOI":"10.3390\/molecules26010049"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"108275","DOI":"10.1016\/j.jddst.2026.108275","article-title":"Bacterial Cellulose-Based Materials for Drug Delivery in Wound Dressing Applications","volume":"120","author":"Madanhire","year":"2026","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.biochi.2026.02.003","article-title":"Overview of Bacterial Cellulose: Biosynthesis Strategies, Functionalization and Biomedical Marketing","volume":"244","author":"Saleh","year":"2026","journal-title":"Biochimie"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Zhong, C. (2020). Industrial-Scale Production and Applications of Bacterial Cellulose. Front. Bioeng. Biotechnol., 8.","DOI":"10.3389\/fbioe.2020.605374"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Pal\u00e1cio, S.B., Penello, S.O., Hodel, K.V.S., Barbosa, W.T., Reis, G.A., Machado, B.A.S., Godoy, A.L.P.C., Tavares, M.I.B., Mahnke, L.C., and Viana Barbosa, J.D. (2025). Commercial, Non-Commercial and Experimental Wound Dressings Based on Bacterial Cellulose: An In-Depth Comparative Study of Physicochemical Properties. Fibers, 13.","DOI":"10.3390\/fib13090127"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"4597","DOI":"10.1007\/s13399-023-05175-9","article-title":"Characterization of Ex Situ Developed Bacterial Cellulose\/ZnO-NPs Nanocomposite for Antimicrobial Evaluation","volume":"15","author":"Saleh","year":"2025","journal-title":"Biomass Convers. Biorefin."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Motelica, L., Ficai, D., Petrisor, G., Oprea, O.-C., Tru\u0219c\u01ce, R.-D., Ficai, A., Andronescu, E., Hudita, A., and Holban, A.M. (2024). Antimicrobial Hydroxyethyl-Cellulose-Based Composite Films with Zinc Oxide and Mesoporous Silica Loaded with Cinnamon Essential Oil. Pharmaceutics, 16.","DOI":"10.3390\/pharmaceutics16091225"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.ijbiomac.2019.03.240","article-title":"A Facile Construction of Bacterial Cellulose\/ZnO Nanocomposite Films and Their Photocatalytic and Antibacterial Properties","volume":"132","author":"Wahid","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s10570-013-9892-8","article-title":"Formation of Nanocrystalline ZnO Particles into Bacterial Cellulose Pellicle by Ultrasonic-Assisted In Situ Synthesis","volume":"20","author":"Katepetch","year":"2013","journal-title":"Cellulose"},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Isopencu, G., Deleanu, I., Busuioc, C., Oprea, O., Surdu, V.-A., Bacalum, M., Stoica, R., and Stoica-Guzun, A. (2023). Bacterial Cellulose\u2014Carboxymethylcellulose Composite Loaded with Turmeric Extract for Antimicrobial Wound Dressing Applications. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24021719"},{"key":"ref_62","first-page":"100995","article-title":"Green Synthesis and Characterization of Zinc Oxide Nanoparticles Using Cayratia pedata Leaf Extract","volume":"26","author":"Jayachandran","year":"2021","journal-title":"Biochem. Biophys. Rep."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"128441","DOI":"10.1016\/j.micres.2026.128441","article-title":"Recent Advances in Gold and Zinc Oxide Nanoparticles: Antibiofilm Action, Mechanisms beyond ROS Generation, and In Vivo Efficacy","volume":"306","author":"Kumarage","year":"2026","journal-title":"Microbiol. Res."}],"container-title":["Polymers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-4360\/18\/9\/1050\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T19:44:31Z","timestamp":1777319071000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-4360\/18\/9\/1050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,26]]},"references-count":63,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["polym18091050"],"URL":"https:\/\/doi.org\/10.3390\/polym18091050","relation":{},"ISSN":["2073-4360"],"issn-type":[{"value":"2073-4360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,26]]}}}