{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T21:08:58Z","timestamp":1778533738276,"version":"3.51.4"},"reference-count":75,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Education and Research, National Authority for Research, Romania","award":["6N\/2023"],"award-info":[{"award-number":["6N\/2023"]}]},{"name":"Ministry of Education and Research, National Authority for Research, Romania","award":["PN 23 26 0103"],"award-info":[{"award-number":["PN 23 26 0103"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Due to biodegradability, functionalization, and sustained release, polymer-based films are widely used in different industries. This study explores a bioactive emulsion-based film obtained using high-methoxy pectin (HMP), Origanum onites L. essential oil, and a hydroalcoholic extract of Thymus vulgaris L., prepared using various emulsion recipes. The emulsions obtained were applied to cellulose supports intended for topical applications. Bioactive textiles were analyzed using SEM-EDS elemental mapping, ATR FT-IR spectroscopy, biocompatibility assessment, antimicrobial activity assays, and analysis of comfort indices. SEM images of textile supports treated with bioactive emulsions confirmed the creation of a film surface and that the homogeneity of the film increases with increasing amount of glycerin, which acts as a plasticizer. Infrared spectra combined with their second derivatives and PCA indicate the presence of oregano essential oil, thyme extract, and pectin on the surface of the cotton. The biocompatibility evaluation of functionalized cotton supports revealed minimal cytotoxic effects on HaCaT human keratinocytes after 24 h of exposure. The results of the analyses showed that bioactive textile supports also exhibit antimicrobial activity. Therefore, the active emulsions with pectin, oregano essential oil, and hydroalcoholic extract of thyme provide biocompatible and antimicrobial active films by applying on cellulosic supports.<\/jats:p>","DOI":"10.3390\/polym18091067","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:26:41Z","timestamp":1777382801000},"page":"1067","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Biocompatible and Antimicrobial Cellulosic Support via Bioactive Emulsion-Based Film"],"prefix":"10.3390","volume":"18","author":[{"given":"Angela","family":"Danila","sequence":"first","affiliation":[{"name":"Faculty of Industrial Design and Business Management, \u201cGheorghe Asachi\u201d Technical University of Iasi, 29 Prof. Dr. Docent D. Mangeron Blvd, 700050 Iasi, Romania"},{"name":"Centre for Research and Innovation in Textiles and Fashion Industry\u2014SMART-Tex-IS, Corp TEX 4, 29 Prof. Dr. Docent D. Mangeron Blvd, 700050 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Chirila","sequence":"additional","affiliation":[{"name":"The National Research-Development Institute for Textiles and Leather Research, 6 Lucretiu P\u0103tr\u0103\u0219canu Str., 030508 Bucuresti, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5740-524X","authenticated-orcid":false,"given":"Carmen-Mihaela","family":"Popescu","sequence":"additional","affiliation":[{"name":"Petru Poni Institute of Macromolecular Chemistry of the Romanian Academy, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania"},{"name":"School of Computing, Engineering and the Built Environment, Edinburgh Napier University, Unit 1, Seven Hills Business Park, 37 Bankhead Crossway South, Edinburgh EH11 4EP, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4883-3346","authenticated-orcid":false,"given":"Ionela Cristina","family":"Voinea","sequence":"additional","affiliation":[{"name":"Faculty of Biology, University of Bucharest, 91\u201395 Splaiul Independentei, 050095 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0982-0040","authenticated-orcid":false,"given":"Cristina-Mihaela","family":"Rimbu","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, Iasi University of Life Sciences, 8 Mihail Sadoveanu Alley, 707027 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5809-0916","authenticated-orcid":false,"given":"Gizem Ceylan","family":"T\u00fcrko\u011flu","sequence":"additional","affiliation":[{"name":"Department of Textile Engineering, Faculty of Engineering, Dokuz Eyl\u00fcl University, Central Campus, 35397 Izmir, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9823-0063","authenticated-orcid":false,"given":"Emil-Ioan","family":"Muresan","sequence":"additional","affiliation":[{"name":"\u201dCristofor Simionescu\u201d Faculty of Chemical Engineering and Environmental Protection, \u201cGheorghe Asachi\u201d Technical University of Iasi, 73 Prof. Dr. Docent D. Mangeron Blvd, 700050 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4924-739X","authenticated-orcid":false,"given":"Mariana","family":"Costea","sequence":"additional","affiliation":[{"name":"Faculty of Industrial Design and Business Management, \u201cGheorghe Asachi\u201d Technical University of Iasi, 29 Prof. Dr. Docent D. Mangeron Blvd, 700050 Iasi, Romania"},{"name":"Centre for Research and Innovation in Textiles and Fashion Industry\u2014SMART-Tex-IS, Corp TEX 4, 29 Prof. Dr. Docent D. Mangeron Blvd, 700050 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5747","DOI":"10.1007\/s00289-021-03826-3","article-title":"Antimicrobial textile: Recent developments and functional perspectives","volume":"79","author":"Gulati","year":"2022","journal-title":"Polym. 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