{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:14:32Z","timestamp":1783350872793,"version":"3.54.6"},"reference-count":52,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008867","name":"the Scientific Research Fund of Zhejiang Provincial Education Department","doi-asserted-by":"publisher","award":["Y202351617"],"award-info":[{"award-number":["Y202351617"]}],"id":[{"id":"10.13039\/501100008867","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Dioctyl adipate (DOA) and dioctyl sebacate (DOS) are widely used cold-resistance plasticizers; however, their low molecular weight and weak polarity result in poor thermal stability and migration resistance. Here, we report the synthesis and performance of bio-based cold-resistance plasticizers derived from trans-aconitic acid with enhanced migration resistance. Tri-n-butyl trans-aconitate (TBTA), tri-n-hexyl trans-aconitate (THTA), and tri-n-octyl trans-aconitate (TOTA) were synthesized via one-step esterification with aliphatic alcohols and applied in poly(vinyl chloride) (PVC). Compared with commercial plasticizers di-(2-ethylhexyl) phthalate (DEHP), tributyl citrate (TBC) and DOA, the synthesized plasticizers demonstrated excellent thermal stability and cold-resistance. After freezing treatment, the Tg values of TBTA\/PVC (18.99 \u00b0C) and THTA\/PVC (20.88 \u00b0C) were lower than those of DEHP\/PVC (22.74 \u00b0C). The branched architecture was supposed to strengthen interactions between plasticizers and PVC, improving volatility resistance and solvent extraction resistance. Compared with DOA\/PVC at 48 h, TBTA\/PVC, THTA\/PVC and TOTA\/PVC displayed volatility mass loss reduction of ~1.5%, 4% and 7%, respectively. Their extraction mass loss in ethanol decreased by 5\u20136%, while in petroleum ether, TBTA\/PVC and TOTA\/PVC dropped by 11.95% and 2.63%, respectively. These bio-based plasticizers are promising alternatives to the poor migration resistance of conventional low-temperature plasticizers.<\/jats:p>","DOI":"10.3390\/polym18131671","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T13:43:14Z","timestamp":1783345394000},"page":"1671","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cold-Resistance Plasticizers Derived from Bio-Based Trans-Aconitic Acid with High Performance on Solvent Extraction Resistance and Volatility Resistance"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9053-7247","authenticated-orcid":false,"given":"Yirui","family":"Shen","sequence":"first","affiliation":[{"name":"The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou 310014, China"},{"name":"School of Materials and Chemical Engineering, Ningbo University of Technology, Ningbo 315211, China"},{"name":"Zhejiang Boxiao Bio-Pharmaceutical Co., Ltd., Hangzhou 311400, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomei","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Materials and Chemical Engineering, Ningbo University of Technology, Ningbo 315211, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangyang","family":"Xiong","sequence":"additional","affiliation":[{"name":"School of Materials and Chemical Engineering, Ningbo University of Technology, Ningbo 315211, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinmeng","family":"He","sequence":"additional","affiliation":[{"name":"School of Materials and Chemical Engineering, Ningbo University of Technology, Ningbo 315211, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingping","family":"Jiang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guizhen","family":"Xing","sequence":"additional","affiliation":[{"name":"Zhejiang Boxiao Bio-Pharmaceutical Co., Ltd., Hangzhou 311400, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"26297","DOI":"10.1039\/D2RA03787D","article-title":"A strategy to prepare internally-plasticized poly(vinyl chloride) by grafting castor oil onto the PVC chain with three different isocyanates as intermediate bridges","volume":"12","author":"Deng","year":"2022","journal-title":"RSC Adv."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"5635","DOI":"10.1039\/D3GC03428C","article-title":"Global environmental and toxicological data of emerging plasticizers: Current knowledge, regrettable substitution dilemma, green solution and future perspectives","volume":"26","author":"Qadeer","year":"2024","journal-title":"Green Chem."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Dziendzio\u0142, P., Wa\u015bkiewicz, S., and Jaszcz, K. 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