{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T09:07:54Z","timestamp":1789117674280,"version":"build-2803163510"},"reference-count":62,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research, Development and Innovation Office, Hungary","award":["K135946"],"award-info":[{"award-number":["K135946"]}]},{"award":["K135946"],"award-info":[{"award-number":["K135946"]}],"id":[{"id":"https:\/\/ror.org\/03g2am276","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>This study reports on a new one-pot copolymerization process by simultaneous oxidative disulfide and \u03b2-thioester formation by reacting bifunctional monomers, 3,6-dioxa-1,8-octane-dithiol (DODT) with diacrylates, poly(ethylene glycol) diacrylate (PEGDA) and 1,6-hexanediol diacrylate (HDODA), in the presence of N,N,N\u2032,N\u2033,N\u2033-pentamethyldiethylenetriamine (PMDETA), as the same base catalyst for both reactions, in air at room temperature with short reaction times. The resulting random copolymers consist of disulfide linkages between DODTs and \u03b2-thioester units formed by thiol-ene Michael addition click reaction. With a stoichiometric DODT\/diacrylate feed ratio, diacrylate-telechelic copolymers are obtained in a single-step polymerization reaction. The Tgs of the P(DODT-co-PEGDA) copolymers are nearly constant at around \u221253 \u00b0C, while it decreases with increasing HDODA content in the P(DODT-co-HDODA) copolymers. Reductive degradation with thiols, such as 2-mercaptoethanol and dithiothreitol, led to chain scission via the disulfide\u2013thiol exchange reaction. Treatment with NaOH solution resulted in further degradation by hydrolysis of the \u03b2-thioester units. These results indicate that these novel copolymers are fully degradable under mild conditions. This new process, applying simultaneous thiol oxidation and thiol-ene reactions, enables to prepare a large variety of sulfur-containing end-functional degradable copolymers useful for a broad range of advanced application possibilities.<\/jats:p>","DOI":"10.3390\/polym18182211","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T08:17:42Z","timestamp":1789114662000},"page":"2211","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Degradable Acrylate-Telechelic Copolymers with Disulfide and \u03b2-Thioester Linkages by Simultaneous Thiol Oxidation and Thiol-Ene Michael Addition Click Reactions with the Same Base Catalyst"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3519-3896","authenticated-orcid":false,"given":"\u00c1kos","family":"Szab\u00f3","sequence":"first","affiliation":[{"name":"Polymer Chemistry and Physics Research Group, Institute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Magyar Tud\u00f3sok krt. 2, H-1117 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"}]},{"given":"Aiman","family":"Aitkazina","sequence":"additional","affiliation":[{"name":"Polymer Chemistry and Physics Research Group, Institute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Magyar Tud\u00f3sok krt. 2, H-1117 Budapest, Hungary"},{"name":"Hevesy Gy\u00f6rgy Doctoral School of Chemistry, Institute of Chemistry, Faculty of Science, E\u00f6tv\u00f6s Lor\u00e1nd University, P\u00e1zm\u00e1ny P\u00e9ter S\u00e9t\u00e1ny 1\/A, H-1117 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"}]},{"given":"Gy\u00f6rgyi","family":"Szarka","sequence":"additional","affiliation":[{"name":"Polymer Chemistry and Physics Research Group, Institute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Magyar Tud\u00f3sok krt. 2, H-1117 Budapest, 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applications","volume":"12","author":"Song","year":"2025","journal-title":"Natl. Sci. Rev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1800650","DOI":"10.1002\/marc.201800650","article-title":"Sulfur chemistry in polymer and materials science","volume":"40","author":"Mutlu","year":"2019","journal-title":"Macromol. Rapid Commun."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"6650","DOI":"10.1039\/D1PY01065D","article-title":"The synthesis of degradable sulfur-containing polymers: Precise control of structure and stereochemistry","volume":"12","author":"Yue","year":"2021","journal-title":"Polym. Chem."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Shi, X., and Zhuang, D. (2026). Thermosets Based on Covalent Bond Exchange: Mechanisms, Properties, and Reprocessing. Polymers, 18.","DOI":"10.3390\/polym18111317"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Szab\u00f3, \u00c1., Szarka, G., Trif, L., Gyarmati, B., Bereczki, L., Iv\u00e1n, B., and Kov\u00e1cs, E. (2022). Poly(dithiophosphate)s, A New Class of Phosphorus- and Sulfur-Containing Functional Polymers by a Catalyst-Free Facile Reaction between Diols and Phosphorus Pentasulfide. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms232415963"},{"key":"ref_6","first-page":"e02044","article-title":"Sustainable inverse vulcanized polymers: Design rules linking comonomer structure, network architecture, and functional performance","volume":"48","author":"Li","year":"2026","journal-title":"Sustain. Mater. Technol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"e202411010","DOI":"10.1002\/anie.202411010","article-title":"Inverse Vulcanization of Activated Norbornenyl Esters\u2014A Versatile Platform for Functional Sulfur Polymers","volume":"63","author":"Grimm","year":"2024","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1021\/acs.biomac.1c01210","article-title":"Poly(disulfide)s: From synthesis to drug delivery","volume":"23","author":"Zhang","year":"2022","journal-title":"Biomacromolecules"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e202501023","DOI":"10.1002\/cssc.202501023","article-title":"Dynamic Disulfide Chemistry for Functional Polymers: Self-Healing, Vitrimer Behavior, and Biochemical\/Electronic Applications","volume":"19","author":"Jin","year":"2026","journal-title":"ChemSusChem"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Li, X., Zhai, Y., Yang, K., Bai, J., Qiu, Y., and Wang, Y. (2024). Preparation and Characterization of a Novel Self-Healing Transparent Polyimide Film Based on Dynamic Disulfide Bonds. Polymers, 16.","DOI":"10.3390\/polym16243461"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1021\/acs.accounts.5c00689","article-title":"Sustainable Design of Dynamic Poly(disulfide)s","volume":"59","author":"Zhang","year":"2026","journal-title":"Acc. Chem. Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"8468","DOI":"10.1021\/acs.macromol.5c00977","article-title":"Dithiolane-Ene Copolymerization: Enabling Tunable, Dynamic Dual-Cure Networks via Real Time UV-VIS\/FTIR Kinetics and Compositional Analysis","volume":"58","author":"Keyser","year":"2025","journal-title":"Macromolecules"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1039\/D5PY00379B","article-title":"Lipoic acid\/ethyl lipoate as cleavable comonomers for synthesis of degradable polymer networks","volume":"16","author":"Dawson","year":"2025","journal-title":"Polym. Chem."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"22728","DOI":"10.1021\/jacs.3c08248","article-title":"Controlled-radical polymerization of \u03b1-lipoic acid: A general route to degradable vinyl copolymers","volume":"145","author":"Albanese","year":"2023","journal-title":"J. Am. Chem. Soc."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e202500194","DOI":"10.1002\/cssc.202500194","article-title":"A Greener and More Scalable Synthesis of Biogenic Polydisulfides from Lipoic Acid","volume":"18","author":"Koelbl","year":"2025","journal-title":"ChemSusChem"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1021\/acsmacrolett.4c00839","article-title":"Versatile and controlled synthesis of degradable, water-soluble bottlebrush polymers with poly(disulfide) backbones derived from \u03b1-lipoic acid","volume":"14","author":"Levkovsky","year":"2025","journal-title":"ACS Macro Lett."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1002\/pol.20240876","article-title":"Telechelic Dithiol Copolymers as Tunable Building Blocks for Synthesizing Multiblock Materials","volume":"63","author":"Czuczola","year":"2025","journal-title":"J. Polym. Sci."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1021\/acsmacrolett.3c00345","article-title":"Mechanisms of Degradation for Polydisulfides: Main Chain Scission, Self-Immolation, or Chain Transfer Depolymerization","volume":"12","author":"Kristensen","year":"2023","journal-title":"ACS Macro Lett."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1039\/D2PY01291J","article-title":"Disulfide-containing monomers in chain-growth polymerization","volume":"14","author":"Pieta","year":"2023","journal-title":"Polym. Chem."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"17886","DOI":"10.1039\/D4NR02494J","article-title":"Alternating vs. random amphiphilic polydisulfides: Aggregation, enzyme activity inhibition and redox-responsive guest release","volume":"16","author":"Bera","year":"2024","journal-title":"Nanoscale"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"6392","DOI":"10.1039\/D5GC01872B","article-title":"Closed-loop recycling of bio-based disulfide vitrimer via a solvent- and waste-free strategy","volume":"27","author":"Guggari","year":"2025","journal-title":"Green Chem."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1700735","DOI":"10.1002\/marc.201700735","article-title":"Entropy-Driven Ring-Opening Disulfide Metathesis Polymerization for the Synthesis of Functional Poly(disulfide)s","volume":"39","author":"Behrendt","year":"2018","journal-title":"Macromol. Rapid Commun."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"114574","DOI":"10.1016\/j.eurpolymj.2026.114574","article-title":"Multifunctional dynamic hydrogels crosslinked with boronic ester and disulfide bonds reinforced with oxidized cellulose nanofibers for self-healing, motion sensing, and controlled drug release","volume":"246","author":"Gharakhloo","year":"2026","journal-title":"Eur. Polym. J."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Zhang, Y., and Zhao, X. (2026). Disulfide-Crosslinked Polyurethane-Modified Asphalt: Balancing Fatigue Resistance and Healing Through Dynamic Covalent Networks. Polymers, 18.","DOI":"10.3390\/polym18050582"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"36568","DOI":"10.1039\/C6RA02824A","article-title":"Disulfide bonds-containing amphiphilic conetworks with tunable reductive-cleavage","volume":"6","author":"Zhang","year":"2016","journal-title":"RSC Adv."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1002\/marc.201400237","article-title":"Telechelic Poly(disulfide)s and Related Block Copolymer","volume":"35","author":"Basak","year":"2014","journal-title":"Macromol. Rapid Commun."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Witt, D. (2008). Recent developments in disulfide bond formation. Synthesis, 2491\u20132509.","DOI":"10.1055\/s-2008-1067188"},{"key":"ref_28","first-page":"2515","article-title":"Synthesis of a novel polysulfide via the reaction of a thiol compound and oxidant towards polymer self-healing application","volume":"25","author":"Nguyen","year":"2022","journal-title":"Sci. Technol. Dev. J."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"249\u2212251","DOI":"10.1002\/macp.1968.021190129","article-title":"Oxidation of dithiols to polydisulfides by means of dimethylsulfoxide","volume":"119","author":"Goethals","year":"1968","journal-title":"Makromol. Chem."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"113254","DOI":"10.1016\/j.colsurfb.2023.113254","article-title":"In situ gelation of thiolated poly(aspartic acid) derivatives through oxidant-free disulfide formation for ophthalmic drug delivery","volume":"225","author":"Gyarmati","year":"2023","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/s41589-026-02142-z","article-title":"Multifaceted roles for persulfide species in redox chemical biology","volume":"22","author":"Nagy","year":"2026","journal-title":"Nat. Chem. Biol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1351\/PAC-CON-11-11-04","article-title":"Green Polymer Chemistry: Living oxidative polymerization of dithiols","volume":"84","author":"Puskas","year":"2012","journal-title":"Pure Appl. Chem."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1021\/bm201395t","article-title":"Green polymer chemistry: Living dithiol polymerization via cyclic intermediates","volume":"13","author":"Rosenthal","year":"2012","journal-title":"Biomacromolecules"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"6504","DOI":"10.3390\/molecules20046504","article-title":"Green polymer chemistry: Investigating the mechanism of radical ring-opening redox polymerization (R3P) of 3,6-Dioxa-1,8- octanedithiol (DODT)","volume":"20","author":"Puskas","year":"2015","journal-title":"Molecules"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1039\/D1PY01426A","article-title":"PolyDODT: A macrocyclic elastomer with unusual properties","volume":"13","author":"Molnar","year":"2022","journal-title":"Polym. Chem."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1021\/acs.macromol.6b02397","article-title":"Synthesis of Biodegradable Polyisobutylene Disulfides by Living Reversible Recombination Radical Polymerization (R3P): Macrocycles?","volume":"50","author":"Puskas","year":"2017","journal-title":"Macromolecules"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"125677","DOI":"10.1016\/j.molliq.2024.125677","article-title":"Synthesis of biodegradable polydisulfides from renewable resources","volume":"411","author":"Polyak","year":"2024","journal-title":"J. Mol. Liq."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"117113","DOI":"10.1016\/j.jelechem.2022.117113","article-title":"Investigation of Poly(3,6-dioxa-1,8-octane-dithiol)-Based Organosulfur Polymer as the Positive Electrode Material in Rechargeable Li-S Battery","volume":"929","author":"Gnanavel","year":"2023","journal-title":"J. Electroanal. Chem."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/cber.190503801106","article-title":"Beitraege zur Kenntniss der ungesaettigten Verbindungen. II. Ueber die Addition von Mercaptanen an ungesaettigte Kohlenwasserstoffen","volume":"38","author":"Posner","year":"1905","journal-title":"Ber. Dtsch. Chem. Ges."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1002\/anie.200903924","article-title":"Thiol-ene click chemistry","volume":"49","author":"Hoyle","year":"2010","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.eurpolymj.2016.02.025","article-title":"Thiol-ene polymerisation: A promising technique to obtain novel biomaterials","volume":"86","author":"Thiago","year":"2017","journal-title":"Eur. Polym. J."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"9867","DOI":"10.1021\/acs.macromol.4c02020","article-title":"Construction and Regulation on Thiol-Acrylate Networks through Binary Polymerization of Thiol-Ene Polymerization and Free Radical Polymerization","volume":"57","author":"Li","year":"2024","journal-title":"Macromolecules"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1039\/D4PY01106F","article-title":"Frontal polymerization of thiol\u2013acrylate covalent adaptable networks","volume":"16","author":"Schmidleitner","year":"2025","journal-title":"Polym. Chem."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"81920","DOI":"10.1039\/C5RA18861J","article-title":"Synthesis of degradable multi-segmented polymers via Michael-addition thiol\u2013ene step-growth polymerization","volume":"5","author":"Vandenbergh","year":"2015","journal-title":"RSC Adv."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"3525","DOI":"10.1016\/j.polymer.2014.05.043","article-title":"Cross-linked degradable poly(\u03b2-thioester) networks via amine-catalyzed thiol-ene click polymerization","volume":"55","author":"Vandenbergh","year":"2014","journal-title":"Polymer"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/pola.26986","article-title":"Facile design of degradable poly(\u03b2-thioester)s with tunable structure and functionality","volume":"52","author":"Zaquen","year":"2014","journal-title":"J. Polym. Sci. Part A Polym. Chem."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1002\/macp.201200470","article-title":"Synthesis of (Bio)-Degradable Poly(\u03b2-thioester)s via Amine Catalyzed Thiol\u2212Ene Click Polymerization","volume":"213","author":"Vandenbergh","year":"2012","journal-title":"Macromol. Chem. Phys."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"228024","DOI":"10.1016\/j.jpowsour.2020.228024","article-title":"In-situ generation of high performance thiol-conjugated solid polymer electrolytes via reliable thiol-acrylate click chemistry","volume":"456","author":"Xuan","year":"2020","journal-title":"J. Power Sources"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"6176","DOI":"10.1021\/acsnano.5c20521","article-title":"In Vivo Programmed Assembly of Polymer\u2013Peptide Conjugates to Overcome Multistage Drug Delivery Barriers","volume":"20","author":"Zhang","year":"2026","journal-title":"ACS Nano"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"5334","DOI":"10.1021\/acsapm.3c00719","article-title":"Photo-Degradable Functional Polyesters from an o-Nitrobenzyl Dithiol: Synthesis and Applications in Herbicide Delivery","volume":"5","author":"Shan","year":"2023","journal-title":"ACS Appl. Polym. Mater."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"2500269","DOI":"10.1002\/marc.202500269","article-title":"Synthesis of pH-Responsive Hyperbranched Polyesters by Thiol-Acrylate Michael Addition Reaction and Versatile Post-Polymerization Functionalization","volume":"46","author":"Dan","year":"2025","journal-title":"Macromol. Rapid Commun."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"113498","DOI":"10.1016\/j.eurpolymj.2024.113498","article-title":"Synthesis of linear and crosslinked isosorbide-containing poly(\u03b2-thioether ester) via amine-catalyzed thiol-Michael addition","volume":"220","author":"Sanaa","year":"2024","journal-title":"Eur. Polym. J."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"113290","DOI":"10.1016\/j.eurpolymj.2024.113290","article-title":"Synthesis of long-chain aliphatic poly(\u03b2-thioester)s via thiol-Michael polyaddition and their applications in noble metal recovery and information encryption","volume":"216","author":"Li","year":"2024","journal-title":"Eur. Polym. J."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Aerts, A., Vovchenko, M., Elahi, S.A., Vinuelas, R.C., De Maeseneer, T., Purino, M., Hoogenboom, R., Van Oosterwyck, H., Jonkers, I., and Cardinaels, R. (2024). A Spontaneous In Situ Thiol-Ene Crosslinking Hydrogel with Thermo-Responsive Mechanical Properties. Polymers, 16.","DOI":"10.2139\/ssrn.4767185"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1021\/acsabm.3c01121","article-title":"Poly-\u03b2-thioester-Based Cross-Linked Nanocarrier for Cancer Cell Selectivity over Normal Cells and Cellular Apoptosis by Triggered Release of Parthenolide, an Anticancer Drug","volume":"7","author":"Dey","year":"2024","journal-title":"ACS Appl. Bio Mater."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Sojdeh, S., Panjipour, A., Yaghmour, A., Arabpour, Z., and Djalilian, A.R. (2025). Click chemistry-based hydrogels for tissue engineering. Gels, 11.","DOI":"10.3390\/gels11090724"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"12001","DOI":"10.1039\/D5RA01104C","article-title":"Biodegradability of poly(ester-thioether)s containing chiral biomass via a Michael-type thiol-ene click reaction","volume":"15","author":"Imamura","year":"2025","journal-title":"RSC Adv."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"123132","DOI":"10.1016\/j.polymer.2020.123132","article-title":"Self-healable and reprocessable acrylate-based elastomers with exchangeable disulfide crosslinks by thiol-ene click chemistry","volume":"212","author":"Gao","year":"2021","journal-title":"Polymer"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1038\/s41467-026-68963-7","article-title":"Synthesis of poly(ester disulfide)s from S8-involved step-growth addition polymerization at ambient temperature","volume":"17","author":"Sun","year":"2026","journal-title":"Nat. Commun."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"12018","DOI":"10.1039\/D6NR00873A","article-title":"Thiol\u2013Acrylate Michael Addition Strategy for the Templated Synthesis of Water-Soluble Poly(\u03b2-Thioester) Nanogel: Superior Encapsulation Stability and UV-Induced Photolysis Mediated On-Demand Guest Release","volume":"18","author":"Mondal","year":"2026","journal-title":"Nanoscale"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1039\/C6PY02145J","article-title":"Polymerization of \u03b1-(halomethyl)acrylates through sequential nucleophilic attack of dithiols using a combination of addition\u2013elimination and click reactions","volume":"8","author":"Kohsaka","year":"2017","journal-title":"Polym. Chem."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"6381","DOI":"10.1021\/ma101069c","article-title":"Nucleophile-Initiated Thiol-Michael Reactions: Effect of Organocatalyst, Thiol, and Ene","volume":"43","author":"Chan","year":"2010","journal-title":"Macromolecules"}],"container-title":["Polymers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-4360\/18\/18\/2211\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T08:33:34Z","timestamp":1789115614000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-4360\/18\/18\/2211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,11]]},"references-count":62,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["polym18182211"],"URL":"https:\/\/doi.org\/10.3390\/polym18182211","relation":{},"ISSN":["2073-4360"],"issn-type":[{"value":"2073-4360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,11]]}}}