{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T13:14:06Z","timestamp":1778937246574,"version":"3.51.4"},"reference-count":45,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T00:00:00Z","timestamp":1507852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>The selection of a solvent or solvent system and the ensuing polymer\u2013solvent interactions are crucial factors affecting the preparation of fibers with multiple morphologies. A range of poly(methylmethacrylate) fibers were prepared by pressurised gyration using acetone, chloroform, N,N-dimethylformamide (DMF), ethyl acetate and dichloromethane as solvents. It was found that microscale fibers with surface nanopores were formed when using chloroform, ethyl acetate and dichloromethane and poreless fibers were formed when using acetone and DMF as the solvent. These observations are explained on the basis of the physical properties of the solvents and mechanisms of pore formation. The formation of porous fibers is caused by many solvent properties such as volatility, solubility parameters, vapour pressure and surface tension. Cross-sectional images show that the nanopores are only on the surface of the fibers and they were not inter-connected. Further, the results show that fibers with desired nanopores (40\u2013400 nm) can be prepared by carefully selecting the solvent and applied pressure in the gyration process.<\/jats:p>","DOI":"10.3390\/polym9100508","type":"journal-article","created":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T11:34:09Z","timestamp":1507894449000},"page":"508","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Evolution of Surface Nanopores in Pressurised Gyrospun Polymeric Microfibers"],"prefix":"10.3390","volume":"9","author":[{"given":"U.","family":"Illangakoon","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, University College London, London WC1E 7JE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suntharavathanan","family":"Mahalingam","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, University College London, London WC1E 7JE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3687-5119","authenticated-orcid":false,"given":"Rupy","family":"Matharu","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, University College London, London WC1E 7JE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohan","family":"Edirisinghe","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, University College London, London WC1E 7JE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2017,10,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"8456","DOI":"10.1021\/ma020444a","article-title":"Micro- and nanostructured surface morphology on electrospun polymer fibers","volume":"35","author":"Megelski","year":"2002","journal-title":"Macromolecules"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1021\/bm401877s","article-title":"Electrospinning bioactive supramolecular polymers from water","volume":"15","author":"Tayi","year":"2014","journal-title":"Biomacromolecules"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1089\/ten.tea.2014.0254","article-title":"Polymer-based reconstruction of the inferior vena cava in rat: Stem cells or rgd peptide?","volume":"21","author":"Pontailler","year":"2015","journal-title":"Tissue Eng. A"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/s41598-017-00181-0","article-title":"Steering surface topographies of electrospun fibers: Understanding the mechanisms","volume":"7","author":"Yazgan","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1002\/marc.201300339","article-title":"Forming of polymer nanofibers by a pressurised gyration process","volume":"34","author":"Mahalingam","year":"2013","journal-title":"Macromol. Rapid Commun."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.cej.2015.05.114","article-title":"Solubility\u2013spinnability map and model for the preparation of fibres of polyethylene (terephthalate) using gyration and pressure","volume":"280","author":"Mahalingam","year":"2015","journal-title":"Chem. Eng. J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1680\/jsuin.16.00007","article-title":"Tailoring the surface of polymeric nanofibres generated by pressurised gyration","volume":"4","author":"Illangakoon","year":"2016","journal-title":"Surf. Innov."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.msec.2016.12.001","article-title":"Gyrospun antimicrobial nanoparticle loaded fibrous polymeric filters","volume":"74","author":"Illangakoon","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3851","DOI":"10.1021\/acs.molpharmaceut.5b00127","article-title":"Development and characterization of amorphous nanofiber drug dispersions prepared using pressurized gyration","volume":"12","author":"Mahalingam","year":"2015","journal-title":"Mol. Pharm."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1002\/mame.201600116","article-title":"Making nonwoven fibrous poly(epsilon-caprolactone) constructs for antimicrobial and tissue engineering applications by pressurized melt gyration","volume":"301","author":"Xu","year":"2016","journal-title":"Macromol. Mater. Eng."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.carbpol.2014.08.007","article-title":"Rheology and pressurised gyration of starch and starch-loaded poly(ethylene oxide)","volume":"114","author":"Mahalingam","year":"2014","journal-title":"Carbohydr. Polym."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"27914","DOI":"10.1039\/c4ra03657c","article-title":"Theoretical selection of solvent for production of electrospun pmma fibers with wrinkled surfaces","volume":"4","author":"Li","year":"2014","journal-title":"RSC Adv."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/pol.1984.130221208","article-title":"Polymer chemistry\u2014The basic concepts, p. C. Hiemenz, Marcel Dekker, New York, 1984, 738 pp. No price given","volume":"22","author":"Feldman","year":"1984","journal-title":"J. Polym. Sci. Polym. Lett. Ed."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"52973","DOI":"10.1039\/C4RA05385K","article-title":"Hierarchically structured pmma fibers fabricated by electrospinning","volume":"4","author":"Li","year":"2014","journal-title":"RSC Adv."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"7689","DOI":"10.1021\/ma071418l","article-title":"Experimental and theoretical investigations of porous structure formation in electrospun fibers","volume":"40","author":"Dayal","year":"2007","journal-title":"Macromolecules"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1002\/marc.201400274","article-title":"Solvent vapor annealing: An efficient approach for inscribing secondary nanostructures onto electrospun fibers","volume":"35","author":"Liu","year":"2014","journal-title":"Macromol. Rapid Commun."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1002\/macp.200700056","article-title":"Impact of solvent on electrospinning of zein and analysis of resulting fibers","volume":"208","author":"Selling","year":"2007","journal-title":"Macromol. Chem. Phys."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/mame.200600135","article-title":"The influence of solvent properties and functionality on the electrospinnability of polystyrene nanofibers","volume":"291","author":"Pattamaprom","year":"2006","journal-title":"Macromol. Mater. Eng."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1007\/s10853-009-4082-7","article-title":"Solvent control of cellulose acetate nanofibre felt structure produced by electrospinning","volume":"45","author":"Haas","year":"2010","journal-title":"J. Mater. Sci."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.polymer.2011.12.018","article-title":"Construction of hierarchical structures by electrospinning or electrospraying","volume":"53","author":"Zheng","year":"2012","journal-title":"Polymer"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1016\/j.matlet.2011.04.039","article-title":"Electrospun porous cellulose acetate fibers from volatile solvent mixture","volume":"65","author":"Celebioglu","year":"2011","journal-title":"Mater. Lett."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"13851","DOI":"10.1039\/c3ra41315b","article-title":"Polymer fibers with hierarchically porous structure: Combination of high temperature electrospinning and thermally induced phase separation","volume":"3","author":"Ye","year":"2013","journal-title":"RSC Adv."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"35160","DOI":"10.1039\/C7RA05812H","article-title":"Surfactant-driven direct synthesis of a hierarchical hollow mgo nanofiber-nanoparticle composite by electrospinning","volume":"7","author":"Sainudeen","year":"2017","journal-title":"RSC Adv."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"41500","DOI":"10.1039\/C4RA05493H","article-title":"Gentamicin-loaded carbonated hydroxyapatite coatings with hierarchically porous structures: Drug delivery properties, bactericidal properties and biocompatibility","volume":"4","author":"Tang","year":"2014","journal-title":"RSC Adv."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/adma.201504313","article-title":"Bioinspired hydroxyapatite\/poly(methyl methacrylate) composite with a nacre-mimetic architecture by a bidirectional freezing method","volume":"28","author":"Bai","year":"2016","journal-title":"Adv. Mater."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.biomaterials.2015.12.024","article-title":"Synthesis and characterization of a new vertebroplasty cement based on gold-containing pmma microspheres","volume":"82","author":"Jacobs","year":"2016","journal-title":"Biomaterials"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"136","DOI":"10.4103\/2152-7806.119535","article-title":"Cranioplasty with polymethylmethacrylate prostheses fabricated by hand using original bone flaps: Technical note and surgical outcomes","volume":"4","year":"2013","journal-title":"Surg. Neur. Int."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.msec.2014.05.016","article-title":"Synthesis and characterization of hybrid silica\/pmma nanoparticles and their use as filler in dental composites","volume":"42","author":"Toledano","year":"2014","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/nature02388","article-title":"Designing materials for biology and medicine","volume":"428","author":"Langer","year":"2004","journal-title":"Nature"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1126\/science.8134835","article-title":"New challenges in biomaterials","volume":"263","author":"Peppas","year":"1994","journal-title":"Science"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1021\/acs.molpharmaceut.5b00804","article-title":"Long-term sustained ciprofloxacin release from pmma and hydrophilic polymer blended nanofibers","volume":"13","author":"Kristl","year":"2016","journal-title":"Mol. Pharm."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0886-3350(13)80981-9","article-title":"Keratometric cylinder and visual performance following phacoemulsification and implantation with silicone small-incision or poly(methyl methacrylate) intraocular lenses","volume":"17","author":"Brint","year":"1991","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nmat789","article-title":"Hierarchical structure formation and pattern replication induced by an electric field","volume":"2","author":"Morariu","year":"2003","journal-title":"Nat Mater"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"3701","DOI":"10.1021\/ma500331w","article-title":"Polymeric janus particles with hierarchical structures","volume":"47","author":"Deng","year":"2014","journal-title":"Macromolecules"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Hansen, C.M. (2007). Hansen Solubility Parameters: A user\u2019s Handbook, CRC Press.","DOI":"10.1201\/9781420006834"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"4177","DOI":"10.1039\/c3ta10242d","article-title":"Double-segregated carbon nanotube-polymer conductive composites as candidates for liquid sensing materials","volume":"1","author":"Pang","year":"2013","journal-title":"J. Mater. Chem. A"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"4142","DOI":"10.1039\/c0jm03779f","article-title":"Novel architecture of carbon nanotube decorated poly(methyl methacrylate) microbead vapour sensors assembled by spray layer by layer","volume":"21","author":"Feller","year":"2011","journal-title":"J. Mater. Chem."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.apsusc.2015.12.176","article-title":"Tunable surface morphology of electrospun pmma fiber using binary solvent","volume":"364","author":"Liu","year":"2016","journal-title":"Appl. Surf. Sci."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"9801","DOI":"10.1021\/acs.chemrev.5b00069","article-title":"Breath figure: A nature-inspired preparation method for ordered porous films","volume":"115","author":"Zhang","year":"2015","journal-title":"Chem. Rev."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"9350","DOI":"10.1039\/c1sm05712j","article-title":"Highly ordered luminescent microporous films prepared from crystalline conjugated rod-coil diblock copolymers of pf-b-psa and their superhydrophobic characteristics","volume":"7","author":"Chiu","year":"2011","journal-title":"Soft Matter"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1126\/science.1057887","article-title":"Three-dimensionally ordered array of air bubbles in a polymer film","volume":"292","author":"Srinivasarao","year":"2001","journal-title":"Science"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"5347","DOI":"10.1021\/la035915g","article-title":"Breath figure patterns prepared by spin coating in a dry environment","volume":"20","author":"Park","year":"2004","journal-title":"Langmuir"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"9137","DOI":"10.1021\/acs.langmuir.7b02344","article-title":"Nanospace-mediated self-organization of nanoparticles in flexible porous polymer templates","volume":"33","author":"Kuroda","year":"2017","journal-title":"Langmuir"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.msec.2015.06.003","article-title":"Physio-chemical and antibacterial characteristics of pressure spun nylon nanofibres embedded with functional silver nanoparticles","volume":"56","author":"Xu","year":"2015","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/j.msec.2016.07.071","article-title":"Beads, beaded-fibres and fibres: Tailoring the morphology of poly(caprolactone) using pressurised gyration","volume":"69","author":"Hong","year":"2016","journal-title":"Mater. Sci. Eng. C"}],"container-title":["Polymers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-4360\/9\/10\/508\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T18:47:16Z","timestamp":1760208436000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-4360\/9\/10\/508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,13]]},"references-count":45,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,10]]}},"alternative-id":["polym9100508"],"URL":"https:\/\/doi.org\/10.3390\/polym9100508","relation":{},"ISSN":["2073-4360"],"issn-type":[{"value":"2073-4360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,13]]}}}