{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:56:46Z","timestamp":1760147806933,"version":"build-2065373602"},"reference-count":25,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>A Cryptococcus subspecies, neoformans, represents the most pathogenic infection for humans, particularly in immunocompromised hosts (e.g., cancer patients, drug users). In the present study, we described a 67-year old woman with non-Hodgkin lymphoma who developed an infectious disease sustained by Cryptococcus neoformans. Biochemical data documented a decrease in lymphocytes count while clinical evaluation was suggestive on meningeal infection. The microbiological analysis of the serum, using a dilution pattern through the CrAg lateral flow assay (Immy, Norman, OK 73069, USA) detected the antigen of Cryptococcus (dilution 1\/1280), and a treatment with liposomal amphotericin B (3 mg\/kg id) plus flucytosine (100 mg\/kg per day orally in four divided doses) were started, showing an improvement of symptoms. This case report suggests that an antigen dilution can be used to perform a rapid diagnosis and to quickly start the pharmacological treatment.<\/jats:p>","DOI":"10.3390\/reports6010011","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T01:39:21Z","timestamp":1677721161000},"page":"11","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Possible New Diagnostic Method for Early Diagnosis of Cryptococcus Infection in Lymphoma Patient Co-Infected with SARS-CoV-2"],"prefix":"10.3390","volume":"6","author":[{"given":"Manuela","family":"Colosimo","sequence":"first","affiliation":[{"name":"Microbiology and Virology Unit, Pugliese-Ciaccio Hospital, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Nistic\u00f2","sequence":"additional","affiliation":[{"name":"Microbiology and Virology Unit, Pugliese-Ciaccio Hospital, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Quintieri","sequence":"additional","affiliation":[{"name":"Operative Unit of Infectious Disease, Pugliese-Ciaccio Hospital, 881000 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annamaria","family":"De Luca","sequence":"additional","affiliation":[{"name":"Operative Unit of Infectious Disease, Pugliese-Ciaccio Hospital, 881000 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0624-923X","authenticated-orcid":false,"given":"Pasquale","family":"Minchella","sequence":"additional","affiliation":[{"name":"Microbiology and Virology Unit, Pugliese-Ciaccio Hospital, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0858-7902","authenticated-orcid":false,"given":"Luca","family":"Gallelli","sequence":"additional","affiliation":[{"name":"Operative Unit of Clinical Pharmacology and Pharmacovigilance, Department of Health Science, University of Catanzaro, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"a019299","DOI":"10.1101\/cshperspect.a019299","article-title":"Fungal diagnostics","volume":"4","author":"Kozel","year":"2014","journal-title":"Cold Spring Harb. 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