{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:36:21Z","timestamp":1760150181038,"version":"build-2065373602"},"reference-count":61,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:00:00Z","timestamp":1697760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Romanian Ministry of Research and Innovation","award":["POC\/161\/6\/3-398\/390074 \/ 09.11.2021"],"award-info":[{"award-number":["POC\/161\/6\/3-398\/390074 \/ 09.11.2021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>Background: Rehabilitation programs applied in cases of COVID-19-related stroke should counteract not only the effects of the stroke but also the effects of long-term COVID-19. As the molecular processes underlying these cases are still not fully understood, and evidence-based clinical outcomes are scarcely documented, there is a valid need to gather information and develop rehabilitation strategies for these patients. The risks, already clarified in the case of stroke, need to be assessed taking into account the coincidence of the two diseases. Endothelial injuries and emboli that develop after the hypercoagulable state of COVID-19 may take longer to heal, and complications may occur during exercise. This case study attempts to determine what the rehabilitation of a COVID-19-related stroke patient should include. The participant was a 64-year-old male with ischemic right middle cerebral artery stroke, left-side hemiplegia, and middle cerebral artery stenosis, and the CT showed a well-defined area of hypoattenuation in the basal ganglia territory involving the right lentiform nucleus, the anterior and posterior limbs of the internal capsule, and the dorsal part of the external capsule. His NIHSS score was 14, and he registered 15 points on the Barthel index. The patient had a COVID-19 infection two weeks before the stroke event. Methods: Conventional physical therapy was combined with adaptive ballistic strength training, a high-intensity interval training regimen, and manual treatment for myofascial release throughout the chronic recovery phase. Our primary goals were gait rehabilitation, muscle strengthening, weakness management, as well as spasticity reduction, while three different rehabilitation approaches were adopted in a single rehabilitation program to improve the outcome and long-term functional recovery of the patient. Results: The patient progressed in almost every aspect of the assessment criteria. This combined approach\u2019s main success was improved gait speed, gait quality, and improved cardiovascular fitness. Take-away message: In the case of a stroke caused by COVID-19, where the endothelium cells are compromised, HIIT may be questionable due to the poor vascular condition. Based on our results, the low-volume HIIT approach proved appropriate and effective.<\/jats:p>","DOI":"10.3390\/reports6040051","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T07:25:22Z","timestamp":1697786722000},"page":"51","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Enhanced Gait Recovery in Chronic Post-COVID-19 Stroke: The Role of Combined Physical Rehabilitation"],"prefix":"10.3390","volume":"6","author":[{"given":"Hunor P\u00e1l","family":"Fodor","sequence":"first","affiliation":[{"name":"Faculty of Natural Sciences, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3834-421X","authenticated-orcid":false,"given":"Hunor","family":"D\u00e1vid","sequence":"additional","affiliation":[{"name":"Faculty of Natural Sciences, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6395-1562","authenticated-orcid":false,"given":"Attila","family":"Czont","sequence":"additional","affiliation":[{"name":"Faculty of Natural Sciences, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Department of Bioengineering, Faculty of Economics, Socio Human Sciences and Engineering, Sapientia Hungarian University of Transylvania, 530104 Miercurea Ciuc, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8037-7216","authenticated-orcid":false,"given":"Ildik\u00f3","family":"Mikl\u00f3ssy","sequence":"additional","affiliation":[{"name":"Faculty of Natural Sciences, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Department of Bioengineering, Faculty of Economics, Socio Human Sciences and Engineering, Sapientia Hungarian University of Transylvania, 530104 Miercurea Ciuc, Romania"},{"name":"C. D. Neni\u021bescu Institute of Organic Chemistry, 060023 Bucure\u0219ti, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7509-748X","authenticated-orcid":false,"given":"K\u00e1lm\u00e1n-Csongor","family":"Orb\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, Faculty of Economics, Socio Human Sciences and Engineering, Sapientia Hungarian University of Transylvania, 530104 Miercurea Ciuc, Romania"},{"name":"Corax-Bioner CEU SA, 530174 Miercurea Ciuc, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6ngyi","family":"Tar","sequence":"additional","affiliation":[{"name":"Faculty of Technical and Human Sciences, Sapientia Hungarian University of Transylvania, 540485 T\u00e2rgu-Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abony","family":"Fodor","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Borsod-Aba\u00faj-Zempl\u00e9n County Central Hospital and University Teaching Hospital, 3526 Miskolc, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zita","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"Faculty of Natural Sciences, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Be\u00e1ta","family":"Albert","sequence":"additional","affiliation":[{"name":"Faculty of Natural Sciences, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Department of Bioengineering, Faculty of Economics, Socio Human Sciences and Engineering, Sapientia Hungarian University of Transylvania, 530104 Miercurea Ciuc, Romania"},{"name":"Corax-Bioner CEU SA, 530174 Miercurea Ciuc, Romania"},{"name":"Laboratory of Molecular Diagnostics, Emergency County Hospital, 530173 Miercurea Ciuc, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6803-1212","authenticated-orcid":false,"given":"P\u00e1l","family":"Salamon","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, Faculty of Economics, Socio Human Sciences and Engineering, Sapientia Hungarian University of Transylvania, 530104 Miercurea Ciuc, Romania"},{"name":"Corax-Bioner CEU SA, 530174 Miercurea Ciuc, Romania"},{"name":"Laboratory of Molecular Diagnostics, Emergency County Hospital, 530173 Miercurea Ciuc, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Stroke Unit Trialists\u2019 Collaboration (2013). Organised Inpatient (Stroke Unit) Care for Stroke. Cochrane Database Syst. Rev., 2013, CD000197.","DOI":"10.1002\/14651858.CD000197.pub3"},{"key":"ref_2","first-page":"279","article-title":"Acute Cerebrovascular Disease following COVID-19: A Single Center, Retrospective, Observational Study","volume":"5","author":"Li","year":"2020","journal-title":"SSRN Electron. J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1001\/jamaneurol.2020.1127","article-title":"Neurologic Manifestations of Hospitalized Patients with Coronavirus Disease 2019 in Wuhan, China","volume":"77","author":"Mao","year":"2020","journal-title":"JAMA Neurol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1136\/jnnp-2020-324927","article-title":"Characteristics and Outcomes of COVID-19 Associated Stroke: A UK Multicentre Case-Control Study","volume":"92","author":"Perry","year":"2021","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1161\/STROKEAHA.120.030335","article-title":"SARS-CoV-2 and Stroke in a New York Healthcare System","volume":"51","author":"Yaghi","year":"2020","journal-title":"Stroke"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.hest.2020.11.001","article-title":"COVID-19 and Stroke: A Review","volume":"2","author":"Qi","year":"2021","journal-title":"Brain Hemorrhages"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"e001156","DOI":"10.1136\/bmjsem-2021-001156","article-title":"Fidelity, Tolerability and Safety of Acute High-Intensity Interval Training after Hospitalisation for COVID-19: A Randomised Cross-over Trial","volume":"7","author":"Foged","year":"2021","journal-title":"BMJ Open Sport Exerc. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s42466-020-00060-6","article-title":"Recovery from Stroke: Current Concepts and Future Perspectives","volume":"2","author":"Grefkes","year":"2020","journal-title":"Neurol. Res. Pract."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"120","DOI":"10.3389\/fneur.2017.00120","article-title":"Spasticity, Motor Recovery, and Neural Plasticity after Stroke","volume":"8","author":"Li","year":"2017","journal-title":"Front. Neurol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3389\/fnsys.2019.00074","article-title":"Principles of Neurorehabilitation after Stroke Based on Motor Learning and Brain Plasticity Mechanisms","volume":"13","author":"Maier","year":"2019","journal-title":"Front. Syst. Neurosci."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"S225","DOI":"10.1044\/1092-4388(2008\/018)","article-title":"Principles of Experience-Dependent Neural Plasticity: Implications for Rehabilitation after Brain Damage","volume":"51","author":"Kleim","year":"2008","journal-title":"J. Speech Lang. Hear. Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jcomdis.2011.04.006","article-title":"Neural Plasticity and Neurorehabilitation: Teaching the New Brain Old Tricks","volume":"44","author":"Kleim","year":"2011","journal-title":"J. Commun. Disord."},{"key":"ref_13","unstructured":"World Health Organization (2017). The Need to Scale up Rehabilitation."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1080\/09638280701191776","article-title":"Rehabilitation Medicine in Countries of Central\/Eastern Europe","volume":"30","author":"Eldar","year":"2008","journal-title":"Disabil. Rehabil."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/01.PHM.0000141125.28611.3E","article-title":"Spasticity: The Misunderstood Part of the Upper Motor Neuron Syndrome","volume":"83","author":"Ivanhoe","year":"2004","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Mehrholz, J., and Carr, J.H. (2012). Physical Therapy for the Stroke Patient: Early Stage Rehabilitation, Thieme.","DOI":"10.1055\/b-005-148891"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Mehrholz, J. (2019). Neurorehabilitation Practice for Stroke Patients. Textb. Stroke Med., 426\u2013448.","DOI":"10.1017\/9781108659574.026"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"104933","DOI":"10.1016\/j.jstrokecerebrovasdis.2020.104933","article-title":"Effects of Joint Mobilization and Stretching on the Range of Motion for Ankle Joint and Spatiotemporal Gait Variables in Stroke Patients","volume":"29","author":"Cho","year":"2020","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"362","DOI":"10.5535\/arm.20060","article-title":"Motor Function in the Late Phase after Stroke: Stroke Survivors\u2019 Perspective","volume":"44","author":"Pekna","year":"2020","journal-title":"Ann. Rehabil. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1177\/0269215507081922","article-title":"How Feasible Is the Attainment of Community Ambulation after Stroke? A Pilot Randomized Controlled Trial to Evaluate Community-Based Physiotherapy in Subacute Stroke","volume":"22","author":"Lord","year":"2008","journal-title":"Clin. Rehabil."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1177\/02692155221145433","article-title":"A Cohesive, Person-Centric Evidence-Based Model for Successful Rehabilitation after Stroke and Other Disabling Conditions","volume":"37","author":"McNaughton","year":"2023","journal-title":"Clin. Rehabil."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1177\/1545968317732668","article-title":"Agreed Definitions and a Shared Vision for New Standards in Stroke Recovery Research: The Stroke Recovery and Rehabilitation Roundtable Taskforce","volume":"31","author":"Bernhardt","year":"2017","journal-title":"Neurorehabil. Neural Repair"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Lee, S.-H. (2017). Stroke Revisited: Diagnosis and Treatment of Ischemic Stroke, Springer.","DOI":"10.1007\/978-981-10-1424-6"},{"key":"ref_24","unstructured":"DiGiovanna, E.L., Schiowitz, S., and Dowling, D.J. (2005). An Osteopathic Approach to Diagnosis and Treatment, Lippincott Williams & Wilkins."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Smith, J. (2005). Structural Bodywork: An Overview, Churchill Livingstone.","DOI":"10.1016\/B978-0-443-10010-9.50007-0"},{"key":"ref_26","first-page":"559","article-title":"Effectiveness of Osteopathy in the Cranial Field and Myofascial Release versus Acupuncture as Complementary Treatment for Children with Spastic Cerebral Palsy: A Pilot Study","volume":"108","author":"Duncan","year":"2008","journal-title":"J. Am. Osteopath. Assoc."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"21","DOI":"10.46858\/VIMSJPT.2105","article-title":"A Comparative Study Between the Immediate Effects of Tendinous Pressure Technique versus Myofascial Release in the Reduction of Spasticity: A Cross over Study","volume":"2","author":"Marathe","year":"2020","journal-title":"Vims J. Phys. Ther."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Cabanas-Vald\u00e9s, R., Calvo-Sanz, J., Serra-Llobet, P., Alcoba-Kait, J., Gonz\u00e1lez-Rueda, V., and Rodr\u00edguez-Rubio, P.R. (2021). The Effectiveness of Massage Therapy for Improving Sequelae in Post-Stroke Survivors. A Systematic Review and Meta-Analysis. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18094424"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1177\/0269215516663009","article-title":"Effectiveness and Safety of Chinese Massage Therapy (Tui Na) on Post-Stroke Spasticity: A Prospective Multicenter Randomized Controlled Trial","volume":"31","author":"Yang","year":"2017","journal-title":"Clin. Rehabil."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1177\/2156587211430833","article-title":"Myofascial Structural Integration: A Promising Complementary Therapy for Young Children with Spastic Cerebral Palsy","volume":"17","author":"Hansen","year":"2012","journal-title":"J. Evid. Based Complement. Altern. Med."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.jbmt.2015.06.009","article-title":"A Pilot Study of Balance Performance Benefit of Myofascial Release, with a Tennis Ball, in Chronic Stroke Patients","volume":"20","author":"Park","year":"2016","journal-title":"J. Bodyw. Mov. Ther."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"e29926","DOI":"10.1097\/MD.0000000000029926","article-title":"Effects of Myofascial Release with Tennis Ball on Spasticity and Motor Functions of Upper Limb in Patients with Chronic Stroke: A Randomized Controlled Trial","volume":"101","author":"Parikh","year":"2022","journal-title":"Medicine"},{"key":"ref_33","first-page":"2","article-title":"Effectiveness of Myofascial Release on Spasticity and Lower Extremity Function in Diplegic Cerebral Palsy: Randomized Controlled Trial","volume":"3","author":"Kumar","year":"2014","journal-title":"Int. J. Phys. Med. Rehabil."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"453","DOI":"10.36678\/ijmaes.2018.v04i01.003","article-title":"Remya Effectiveness of Myofascial Release in Reduction of Hamstrings Spasticity among Diplegic Cerebral Palsy Children","volume":"4","author":"Paul","year":"2018","journal-title":"Int. J. Med. Exerc. Sci."},{"key":"ref_35","first-page":"69","article-title":"Effect of Myofascial Release on Spastic Muscles and Functional Outcome in Chronic Stroke Subject\u2014A Randomized Control Trial","volume":"10","author":"Mewada","year":"2021","journal-title":"Int. J. Sci. Res."},{"key":"ref_36","first-page":"29","article-title":"A Preliminary Study of Myofascial Release Technique Effect on the Range of Hip Flexion, Knee Flexion, and Ankle Dorsiflexion Motion at Affected Lower Extremity in Individuals with Chronic Stroke","volume":"54","author":"Intanon","year":"2021","journal-title":"JAMS"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/00002060-199903000-00007","article-title":"Analysis of The Clinical Factors Determining Natural and Maximal Gait Speeds in Adults with a Stroke","volume":"78","author":"Nadeau","year":"1999","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1191\/0269215504cr699oa","article-title":"Outcomes of Progressive Resistance Strength Training following Stroke: A Systematic Review","volume":"18","author":"Morris","year":"2004","journal-title":"Clin. Rehabil."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0004-9514(06)70003-4","article-title":"Strengthening Interventions Increase Strength and Improve Activity after Stroke: A Systematic Review","volume":"52","author":"Ada","year":"2006","journal-title":"Aust. J. Physiother."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1097\/PHM.0000000000000058","article-title":"Strength Training for Walking in Neurologic Rehabilitation Is Not Task Specific: A Focused Review","volume":"93","author":"Williams","year":"2014","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1177\/0269215520932964","article-title":"Resistance Training in Stroke Rehabilitation: Systematic Review and Meta-Analysis","volume":"34","author":"Veldema","year":"2020","journal-title":"Clin. Rehabil."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1161\/01.STR.0000181076.91805.89","article-title":"Treadmill Exercise Rehabilitation Improves Ambulatory Function and Cardiovascular Fitness in Patients with Chronic Stroke a Randomized, Controlled Trial","volume":"36","author":"Macko","year":"2005","journal-title":"Stroke"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1177\/1545968313496329","article-title":"Characteristics of Exercise Training Interventions to Improve Cardiorespiratory Fitness after Stroke: A Systematic Review with Meta-Analysis","volume":"27","author":"Marsden","year":"2013","journal-title":"Neurorehabilit. Neural Repair"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Yamin, G., Shahid, Z., Ghafoor, F., Idress, H., Babur, N., and Hayat, K. (2022). Comparison of the Effectiveness of Aerobic Training with Conventional Physical Therapy Treatment in Improving the Quality of Life in Chronic Stroke Patients. Preprint.","DOI":"10.21203\/rs.3.rs-2279515\/v1"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"164","DOI":"10.3389\/fnagi.2016.00164","article-title":"Influence of Aerobic Training and Combinations of Interventions on Cognition and Neuroplasticity after Stroke","volume":"8","author":"Constans","year":"2016","journal-title":"Front. Aging Neurosci."},{"key":"ref_46","unstructured":"Canadian Partnership for Stroke Recovery (2013). Clinician\u2019s Guide Aerobic Exercise after Stroke, Canadian Partnership for Stroke Recovery."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1093\/ptj\/pzz153","article-title":"Aerobic Exercise Recommendations to Optimize Best Practices in Care after Stroke: AEROBICS 2019 Update","volume":"100","author":"Billinger","year":"2020","journal-title":"Phys. Ther."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1161\/01.STR.20.7.864","article-title":"Measurements of Acute Cerebral Infarction: A Clinical Examination Scale","volume":"20","author":"Brott","year":"1989","journal-title":"Stroke"},{"key":"ref_49","first-page":"61","article-title":"Functional evaluation: The barthel index","volume":"14","author":"Fi","year":"1965","journal-title":"Md. State Med. J."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/ptj\/67.2.206","article-title":"Interrater Reliability of a Modified Ashworth Scale of Muscle Spasticity","volume":"67","author":"Bohannon","year":"1987","journal-title":"Phys. Ther."},{"key":"ref_51","unstructured":"Hislop, H.J., and Montgomery, J. (2007). Daniels and Worthingham\u2019s Muscle Testing: Techniques of Manual Examination, Saunders."},{"key":"ref_52","unstructured":"Norkin, C.C., and Joyce White, D. (2009). Measurement of Joint Motion: A Guide to Goniometry, F.A. Davis Company."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3233\/NRE-210026","article-title":"Distance-Limited Walk Tests Post-Stroke: A Systematic Review of Measurement Properties","volume":"48","author":"Cheng","year":"2021","journal-title":"NeuroRehabilitation"},{"key":"ref_54","first-page":"783","article-title":"The Six-Minute Walk Test","volume":"48","author":"Enright","year":"2003","journal-title":"Respir. Care"},{"key":"ref_55","unstructured":"Portney, L.G. (2020). Foundations of Clinical Research: Applications to Evidence-Based Practice, F.A. Davis Company. [4th ed.]."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1177\/1545968318766663","article-title":"High-Intensity Interval Training after Stroke: An Opportunity to Promote Functional Recovery, Cardiovascular Health, and Neuroplasticity","volume":"32","author":"Crozier","year":"2018","journal-title":"Neurorehabil. Neural Repair"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1310\/tsr1904-353","article-title":"Effect of High Aerobic Intensity Interval Treadmill Walking in People with Chronic Stroke: A Pilot Study with One Year Follow-Up","volume":"19","author":"Gjellesvik","year":"2012","journal-title":"Top. Stroke Rehabil."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"709","DOI":"10.2340\/16501977-0838","article-title":"Speed-Dependent Treadmill Training Is Effective to Improve Gait and Balance Performance in Patients with Sub-Acute Stroke","volume":"43","author":"Lau","year":"2011","journal-title":"J. Rehabil. Med."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1310\/tsr2004-317","article-title":"High-Intensity Interval Training in Stroke Rehabilitation","volume":"20","author":"Boyne","year":"2013","journal-title":"Top. Stroke Rehabil."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"493","DOI":"10.3233\/NRE-210326","article-title":"Effects of Bobath Treatment and Specific Mobilizations on Gait in Stroke Patients: A Randomized Clinical Trial","volume":"50","author":"Jurak","year":"2022","journal-title":"NeuroRehabilitation"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1177\/0269215517732820","article-title":"Effectiveness of Myofascial Release in Treatment of Chronic Musculoskeletal Pain: A Systematic Review","volume":"32","author":"Laimi","year":"2018","journal-title":"Clin. Rehabil."}],"container-title":["Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2571-841X\/6\/4\/51\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:10:14Z","timestamp":1760130614000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2571-841X\/6\/4\/51"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,20]]},"references-count":61,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["reports6040051"],"URL":"https:\/\/doi.org\/10.3390\/reports6040051","relation":{},"ISSN":["2571-841X"],"issn-type":[{"type":"electronic","value":"2571-841X"}],"subject":[],"published":{"date-parts":[[2023,10,20]]}}}