{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:45:42Z","timestamp":1760143542985,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T00:00:00Z","timestamp":1708128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>Hidradenitis suppurativa (HS), a challenging dermatological condition, can be described as a chronic, painful, follicular, occlusive disease that is characterized by painful nodules, abscesses, and sinus tracts generally located in the intertriginous skin areas. This disorder places a considerable burden on affected individuals and often leads to significant impairment in quality of life for those grappling with its persistent and recurrent nature. We present the case of a 20-year-old male patient known to have ulcerative proctitis and diagnosed with hidradenitis suppurativa in 2020, for which he underwent various topical and systemic treatments, with periods of remission and recurrent flares without managing to obtain complete remission of HS. In our dermatology service, the patient underwent two surgical unroofing procedures combined with punch debridement, with the wounds being allowed to heal by secondary intention. This choice of treatment delivered great results with favorable outcomes, without recurrence of the lesions, proving to be an effective method for managing HS. By presenting this case, we underline the role of surgical procedures in managing HS, and our desire is to emphasize the importance of comprehensive understanding of this enigmatic and complex condition for more effective management strategies in patients with refractory disease.<\/jats:p>","DOI":"10.3390\/reports7010013","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T03:18:38Z","timestamp":1708312718000},"page":"13","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hidradenitis Suppurativa in Association with Ulcerative Proctitis: Surgical Management in a Refractory Case to Topical and Systemic Treatment"],"prefix":"10.3390","volume":"7","author":[{"given":"Ioana-Valentina","family":"Stoenic\u0103","sequence":"first","affiliation":[{"name":"Dermatology Department, Elias University Emergency Hospital, 011461 Bucharest, Romania"},{"name":"Department of Dermatovenerology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihai Cristian","family":"Dumitra\u0219cu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Obstetrics and Gynecology, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4890-0978","authenticated-orcid":false,"given":"Aida","family":"Petca","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Obstetrics and Gynecology, Elias University Emergency Hospital, 011461 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4496-1535","authenticated-orcid":false,"given":"R\u0103zvan-Cosmin","family":"Petca","sequence":"additional","affiliation":[{"name":"Department of Urology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Urology, \u201cProfessor Doctor Theodor Burghele\u201d Clinical Hospital, 061344 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florica","family":"\u0218andru","sequence":"additional","affiliation":[{"name":"Dermatology Department, Elias University Emergency Hospital, 011461 Bucharest, Romania"},{"name":"Department of Dermatovenerology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1365-4632.2004.02536.x","article-title":"\u201cHidradenitis suppurativa\u201d is acne inversa! An appeal to (finally) abandon a misnomer","volume":"44","author":"Sellheyer","year":"2005","journal-title":"Int. J. Dermatol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1111\/j.1468-3083.2009.03356.x","article-title":"Hidradenitis suppurativa","volume":"23","author":"Revuz","year":"2009","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1159\/000453355","article-title":"Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa","volume":"232","author":"Kouris","year":"2016","journal-title":"Dermatology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1111\/bjd.19435","article-title":"The epidemiology of hidradenitis suppurativa","volume":"183","author":"Ingram","year":"2020","journal-title":"Br. J. Dermatol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.jaad.2017.02.005","article-title":"Incidence of hidradenitis suppurativa in the United States: A sex- and age-adjusted population analysis","volume":"77","author":"Garg","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1600-0625.2008.00712_1.x","article-title":"What causes hidradenitis suppurativa?","volume":"17","author":"Kurzen","year":"2008","journal-title":"Exp. Dermatol."},{"key":"ref_7","unstructured":"Ingram, J.R., Dellavalle, R.P., Owen, C., and Ofori, A.O. (2023). Hidradenitis Suppurativa: Pathogenesis, Clinical Features, and Diagnosis, Wolters Kluwer. UpToDate."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jaad.2008.06.020","article-title":"Prevalence and factors associated with hidradenitis suppurativa: Results from two case-control studies","volume":"59","author":"Revuz","year":"2008","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1001\/jamadermatol.2019.0891","article-title":"Association of Hidradenitis Suppurativa with Inflammatory Bowel Disease","volume":"155","author":"Chen","year":"2019","journal-title":"JAMA Dermatol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1365-2133.2009.09430.x","article-title":"Hidradenitis suppurativa and inflammatory bowel disease: Are they associated? Results of a pilot study","volume":"162","author":"Florencia","year":"2010","journal-title":"Br. J. Dermatol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0007-1226(03)00177-2","article-title":"Hidradenitis suppurativa: Pathogenesis and management","volume":"56","author":"Slade","year":"2003","journal-title":"Br. J. Plast. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.jaad.2014.11.017","article-title":"Correlation of early-onset hidradenitis suppurativa with stronger genetic susceptibility and more widespread involvement","volume":"72","author":"Deckers","year":"2015","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1111\/bjd.14038","article-title":"Diagnostic delay in hidradenitis suppurativa is a global problem","volume":"173","author":"Saunte","year":"2015","journal-title":"Br. J. Dermatol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"S51","DOI":"10.12788\/j.sder.0092","article-title":"Natural history, presentation, and diagnosis of hidradenitis suppurativa","volume":"33","author":"Micheletti","year":"2014","journal-title":"Semin. Cutan. Med. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jaad.2009.02.013","article-title":"Clinical characteristics of a series of 302 French patients with hidradenitis suppurativa, with an analysis of factors associated with disease severity","volume":"61","author":"Revuz","year":"2009","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1111\/bjd.15748","article-title":"Development and validation of the International Hidradenitis Suppurativa Severity Score System (IHS4), a novel dynamic scoring system to assess HS severity","volume":"177","author":"Zouboulis","year":"2017","journal-title":"Br. J. Dermatol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jaad.2009.08.001","article-title":"Hidradenitis suppurativa and smoking","volume":"62","author":"Simonart","year":"2010","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejphar.2011.08.047","article-title":"Pathogenesis and pharmacotherapy of Hidradenitis suppurativa","volume":"672","author":"Nazary","year":"2011","journal-title":"Eur. J. Pharmacol."},{"key":"ref_19","unstructured":"Ingram, J.R., Dellavalle, R.P., Owen, C., and Ofori, A.O. (2023). Hidradenitis Suppurativa: Management, Wolters Kluwer. UpToDate."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/j.1524-4725.2011.02186.x","article-title":"Hidradenitis suppurativa: Surgical and other management techniques","volume":"38","author":"Ellis","year":"2012","journal-title":"Dermatol. Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jaad.2016.08.031","article-title":"Inflammatory bowel disease is associated with hidradenitis suppurativa: Results from a multicenter cross-sectional study","volume":"76","author":"Deckers","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1016\/j.jid.2016.05.102","article-title":"The Association between Hidradenitis Suppurativa and Crohn\u2019s Disease: In Search of the Missing Pathogenic Link","volume":"136","author":"Jemec","year":"2016","journal-title":"J. Investig. Dermatol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1071616","DOI":"10.3389\/fimmu.2023.1071616","article-title":"Causal association between inflammatory bowel disease and hidradenitis suppurativa: A two-sample bidirectional Mendelian randomization study","volume":"14","author":"Bao","year":"2023","journal-title":"Front. Immunol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.cgh.2015.04.180","article-title":"Features of Patients with Crohn\u2019s Disease and Hidradenitis Suppurativa","volume":"14","author":"Kamal","year":"2016","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_25","unstructured":"Orgill, D.P., Jeschke, M.G., and Owen, C. (2023). Surgical Management of Hidradenitis Suppurativa, Wolters Kluwer. UpToDate."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1097\/DSS.0000000000000806","article-title":"Surgical Management of Hidradenitis Suppurativa: Outcomes of 590 Consecutive Patients","volume":"42","author":"Kohorst","year":"2016","journal-title":"Dermatol. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/jdv.12966","article-title":"European S1 guideline for the treatment of hidradenitis suppurativa\/acne inversa","volume":"29","author":"Zouboulis","year":"2015","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.ijwd.2019.11.004","article-title":"A concise clinician\u2019s guide to therapy for hidradenitis suppurativa","volume":"6","author":"Nesbitt","year":"2020","journal-title":"Int. J. Women\u2019s Dermatol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.jaad.2016.06.049","article-title":"Intralesional triamcinolone for flares of hidradenitis suppurativa (HS): A case series","volume":"75","author":"Riis","year":"2016","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.1016\/j.jaad.2015.07.043","article-title":"New and traditional surgical approaches to hidradenitis suppurativa","volume":"73","author":"Danby","year":"2015","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1365-2230.2009.03377.x","article-title":"Resorcinol peels as a possible self-treatment of painful nodules in hidradenitis suppurativa","volume":"35","author":"Boer","year":"2010","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1056\/NEJMoa1504370","article-title":"Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa","volume":"375","author":"Kimball","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"ref_33","unstructured":"PubMed (2023, December 12). Four-Weekly Infliximab in the Treatment of Severe Hidradenitis Suppurativa, Available online: https:\/\/pubmed.ncbi.nlm.nih.gov\/24641123\/."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0140-6736(23)00022-3","article-title":"Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): Week 16 and week 52 results of two identical, multicentre, randomised, placebo-controlled, double-blind phase 3 trials","volume":"401","author":"Kimball","year":"2023","journal-title":"Lancet"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.jaad.2009.12.018","article-title":"Deroofing: A tissue-saving surgical technique for the treatment of mild to moderate hidradenitis suppurativa lesions","volume":"63","author":"Prens","year":"2010","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/PRS.0000000000007677","article-title":"Plastic Surgical Management of Hidradenitis Suppurativa","volume":"147","author":"Taylor","year":"2021","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.det.2015.08.007","article-title":"Surgical Procedures in Hidradenitis Suppurativa","volume":"34","author":"Janse","year":"2016","journal-title":"Dermatol. Clin."}],"container-title":["Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2571-841X\/7\/1\/13\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:01:03Z","timestamp":1760104863000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2571-841X\/7\/1\/13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,17]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,3]]}},"alternative-id":["reports7010013"],"URL":"https:\/\/doi.org\/10.3390\/reports7010013","relation":{},"ISSN":["2571-841X"],"issn-type":[{"type":"electronic","value":"2571-841X"}],"subject":[],"published":{"date-parts":[[2024,2,17]]}}}