{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T17:23:43Z","timestamp":1780853023968,"version":"3.54.1"},"reference-count":20,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T00:00:00Z","timestamp":1733875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the Mahidol Norway Capacity Building Initiative"},{"name":"the faculty of Graduate studies, Mahidol University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>Background: Mosquito-borne diseases such as dengue and chikungunya are endemic to tropical regions and are common causes of acute febrile illness in both adults and children. The Philippines, home to more than one hundred million residents and visited by several million tourists each year, is one such region where the risk of these diseases is endemic. Objective and Methods: To better understand the detailed situation, we estimated the proportion of these diseases in the community by conducting a prospective observational study in four provincial hospitals of Davao de Oro, Philippines, from February 2019 to February 2020. Sera from 382 study participants were used for laboratory confirmation of dengue or chikungunya by serology. Results: Dengue was diagnosed in 57.1%, chikungunya in 7.07%, and coinfection with both dengue and chikungunya in 7.3%, while the etiology was undetermined in 35.9% of the study participants. Common clinical symptoms included fever, headache, and a rash, which were overlapping symptoms that were clinically indistinguishable at the presentation to the hospital, necessitating laboratory diagnostics. Conclusions: The identification of the presence of chikungunya in Davao de Oro calls for increased awareness, improved diagnostics, and integrated disease control measures to manage outbreaks that can occur in dengue-endemic regions.<\/jats:p>","DOI":"10.3390\/reports7040112","type":"journal-article","created":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T06:44:05Z","timestamp":1733899445000},"page":"112","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical and Epidemiological Characteristics of Chikungunya and Dengue Infections in Provincial Hospitals of Davao de Oro, Philippines"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1665-3716","authenticated-orcid":false,"suffix":"Jr.","given":"Nestor","family":"Arce","sequence":"first","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"},{"name":"Jose Maria College Foundation, Inc., College of Medicine, Davao City 8000, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7536-8964","authenticated-orcid":false,"given":"Kobporn","family":"Boonnak","sequence":"additional","affiliation":[{"name":"Department of Immunology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9891-6961","authenticated-orcid":false,"given":"Lee Thunder","family":"Bernasor","sequence":"additional","affiliation":[{"name":"Jose Maria College Foundation, Inc., College of Medicine, Davao City 8000, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Joy","family":"Salas","sequence":"additional","affiliation":[{"name":"College of Nursing, University of the Immaculate Conception, Davao City 8000, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia","family":"Putri","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4635-3701","authenticated-orcid":false,"given":"Pyae Linn","family":"Aung","sequence":"additional","affiliation":[{"name":"Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4812-6334","authenticated-orcid":false,"given":"Hisham Ahmed","family":"Imad","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"},{"name":"Center for Infectious Diseases Education and Research, Department of Viral Infections, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wirongrong","family":"Chierakul","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"},{"name":"Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9270-3720","authenticated-orcid":false,"given":"Viravarn","family":"Luvira","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjaluck","family":"Phonrat","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5896-1961","authenticated-orcid":false,"given":"Weerapong","family":"Phumratanaprapin","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakaykaew","family":"Charunwatthana","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"},{"name":"Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"622","DOI":"10.4269\/ajtmh.18-0407","article-title":"Etiologies of Acute Undifferentiated Febrile Illness in Bangkok, Thailand","volume":"100","author":"Luvira","year":"2019","journal-title":"Am. 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