{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:35:41Z","timestamp":1760060141067,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>Background and Clinical Significance: Neuroleptic malignant syndrome (NMS) is a life-threatening condition usually caused by the exposure to antipsychotics. This case report presents a catatonia syndrome that may have developed in the context of a moderate NMS. Case Presentation: An 18-year-old male patient presented with a treatment-resistant catatonia syndrome that debuted 2 weeks prior to the presentation (creatin kinase levels = 4908 U\/L, maximum temperature = 38.9\u00b0C, white blood count = 13.20 \u00d7 109\/L, Bush\u2013Francis Catatonia Rating Scale = 30 points). Possible organic causes of catatonia were ruled out, according to the negative results obtained. The patient\u2019s condition improved under benzodiazepine treatment and he was later discharged. After discharge, the catatonia was attributed to a possible NMS with moderate severity. The diagnosis was supported by NMS Diagnosis Criteria Score = 85 points and the presence of Levenson\u2019s triad. Conclusions: This case highlights the concomitant manifestation of both catatonia and NMS in the same patient and the difficulty of establishing a correct diagnosis involving both entities.<\/jats:p>","DOI":"10.3390\/reports8030134","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T09:41:17Z","timestamp":1754300477000},"page":"134","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Catatonia in a Possible Case of Moderate Neuroleptic Malignant Syndrome: A Case Report"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5980-6963","authenticated-orcid":false,"given":"Daniel","family":"Ungureanu","sequence":"first","affiliation":[{"name":"Department Pharmacy I, Discipline of Pharmaceutical Chemistry, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 41 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"},{"name":"\u201cProf. Dr. Ion Chiricu\u021b\u0103\u201d Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania"},{"name":"Department Pharmacy II, Discipline of Clinical Pharmacy, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 12 Ion Creang\u0103 Street, 400010 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia-\u0218tefania","family":"Mitrea","sequence":"additional","affiliation":[{"name":"Clinical Hospital of Infectious Diseases, 23 Iuliu Moldovan Street, 400003 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvina","family":"Ilu\u021b","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Faculty of Nursing and Health Sciences, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 8 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"Talo\u0219","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Faculty of Medicine, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 8 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u0103t\u0103lina-Angela","family":"Cri\u0219an","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Discipline of Psychiatry and Pediatric Psychiatry, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 43 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"},{"name":"First Psychiatric Clinic, Cluj County Emergency Clinical Hospital, 43 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"570","DOI":"10.3390\/neurolint13040057","article-title":"Catatonia: Clinical Overview of the Diagnosis, Treatment, and Clinical Challenges","volume":"13","author":"Edinoff","year":"2021","journal-title":"Neurol. Int."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.schres.2022.06.003","article-title":"The Origins of Catatonia\u2014Systematic Review of Historical Texts between 1800 and 1900","volume":"263","author":"Hirjak","year":"2024","journal-title":"Schizophr. Res."},{"key":"ref_3","unstructured":"Cri\u0219an, C., Moisuc, C.-R., and Ungureanu, D. (2024). Sindromul Catatonic. Urgen\u021be Psihiatrice, Editura Medical\u0103 Universitar\u0103 \u201cIuliu Ha\u021bieganu\u201d."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"42","DOI":"10.26416\/Psih.68.1.2022.6310","article-title":"Dissociative Stupor in Young Adults. Challenges in Differential Diagnosis and Treatment Management","volume":"1","author":"Pop","year":"2022","journal-title":"Psihiatru.ro"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Cri\u0219an, C.A., Milhem, Z., Stretea, R., \u021aa\u021ba, I.-M., Chereche\u0219, R.M., and Miclu\u021bia, I.V. (2023). 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