{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T05:11:38Z","timestamp":1760505098932,"version":"build-2065373602"},"reference-count":14,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union-NextGenerationEU","award":["BG-RRP-2.004-0009-C02"],"award-info":[{"award-number":["BG-RRP-2.004-0009-C02"]}]},{"DOI":"10.13039\/501100006379","name":"Medical University\u2014Varna","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006379","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>Background and Clinical Significance: Fetus papyraceus is a term describing fetal findings associated with miscarriage, wherein the fetus is not expelled, remains in the uterine cavity, and is compressed by neighboring structures, with an inability for fetal resorption due to advanced pregnancy. Case Presentation: Herein, we present the case of a 33-year-old primigravida with two previous presentations to our institution due to emotional stress without evidence of physical abuse, the last one being at the 14th week of pregnancy. The latest presentation was with complaints of intermittent lower abdominal pain and an outpatient gynecology consultation describing fetal demise, with fetal parameters corresponding to demise in the 15th to 16th week of gestation. Pregnancy termination was performed with the specimen sent for pathology, revealing fragmented placental parts, which, on section, were firm, with greyish areas and notable calcification, fragments of an umbilical cord appeared normal, and a significantly compressed fetus, which was flattened in the anteroposterior aspect with significant compressive deformation of the limbs\u2014fetus papyraceus characteristics. Histology of the placental fragments revealed fibrin thrombi in large blood vessels, intense fibrosis of the villi with focal fibrin extravasation, and focal necrosis and inflammation, as well as extensive calcium deposits. Conclusions: Fetus papyraceus is a rare complication of intrauterine demise and fetal compression, which can vary in its degree of presenting severity and requires the co-occurrence of specific conditions. The condition is rarely associated with singleton pregnancies.<\/jats:p>","DOI":"10.3390\/reports8040203","type":"journal-article","created":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T13:13:27Z","timestamp":1760361207000},"page":"203","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case Report of Fetus Papyraceus in Singleton Pregnancy"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6950-0615","authenticated-orcid":false,"given":"George","family":"Stoyanov","sequence":"first","affiliation":[{"name":"Department of Pathology, Multiprofile Hospital for Active Treatment, 9700 Shumen, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivaylo","family":"Balabanov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Multiprofile Hospital for Active Treatment, 9700 Shumen, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetoslava","family":"Zhivkova","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Multiprofile Hospital for Active Treatment, 9700 Shumen, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hristo","family":"Popov","sequence":"additional","affiliation":[{"name":"Department of General and Clinical Pathology, Forensic Medicine and Deontology, Faculty of Medicine, Medical University\u2014Varna, 9000 Varna, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"ref_1","first-page":"414","article-title":"Fetus Papyraceus in Twin Pregnancy: A Rare Case Report","volume":"50","author":"Dharwadkar","year":"2023","journal-title":"J. Sci. Soc."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0301-2115(99)00053-6","article-title":"Fetus Papyraceous: An Unusual Cause of Obstructed Labour","volume":"86","author":"Lau","year":"1999","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"132","DOI":"10.5001\/omj.2014.32","article-title":"Conservative Management of Fetus Papyraceus: A Report of Two Cases","volume":"29","author":"Dahiya","year":"2014","journal-title":"Oman Med. J."},{"key":"ref_4","unstructured":"Inan, C., Sayin, N., Erzincan, S., Uzun, I., Sutcu, H., and Varol, F. (2016, January 26\u201330). A Case of Fetus Papyraceus. Proceedings of the 15th World Congress in Fetal Medicine, Palma, Spain."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"119","DOI":"10.4103\/jpgm.JPGM_400_18","article-title":"Incidentally Diagnosed Fetus Compressus on Placental Examination","volume":"65","author":"Chikhale","year":"2019","journal-title":"J. Postgrad. Med."},{"key":"ref_6","first-page":"313","article-title":"Fetus Compressus and Fetus Papyraceous. Clinical Differences (Report of Three Cases)","volume":"79","author":"Luna","year":"2011","journal-title":"Ginecol. Obstet. Mex."},{"key":"ref_7","first-page":"C28","article-title":"Fetus Papyraceus: A Rare Case Report","volume":"2","author":"Masamatti","year":"2015","journal-title":"Ann. Pathol. Lab. Med."},{"key":"ref_8","first-page":"35","article-title":"Aborto unifetal em gesta\u00e7\u00e3o gemelar com presen\u00e7a de feto papir\u00e1ceo","volume":"4","author":"Neto","year":"2024","journal-title":"Rev. Cient\u00edfica Cerem-Go"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.18203\/2320-1770.ijrcog20150461","article-title":"Twin Foetus Papyraceous in Triplet Pregnancy","volume":"4","author":"Gulati","year":"2015","journal-title":"Int. J. Reprod. Contracept. Obs. Gynecol."},{"key":"ref_10","first-page":"289","article-title":"Aplasia Cutis Congenita in a Newborn Child Associated with Two Fetus Papyraceous","volume":"23","author":"Simic","year":"2015","journal-title":"Acta Dermatovenerol. Croat."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4038\/sljpm.v2i1.37","article-title":"Case History Neonate with Aplasia Cutis Congenita Associated with Foetus Papyraceus","volume":"2","author":"Ws","year":"2021","journal-title":"Sri Lanka J. Perinat. Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"161","DOI":"10.4103\/ijpd.ijpd_44_23","article-title":"Aplasia Cutis Congenita Associated with a Fetus Papyraceus: A Case Report","volume":"25","author":"Souarji","year":"2024","journal-title":"Indian J. Paediatr. Dermatol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jdcr.2019.02.015","article-title":"Type V Aplasia Cutis Congenita with Fetus Papyraceus","volume":"5","author":"Snyder","year":"2019","journal-title":"JAAD Case Rep."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1080\/01443615.2017.1286305","article-title":"Aplasia Cutis Congenita with Foetus Papyraceus: Case Report and Review of the Literature","volume":"37","author":"Uzuner","year":"2017","journal-title":"J. Obstet. Gynaecol. Lahore"}],"container-title":["Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2571-841X\/8\/4\/203\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T04:37:17Z","timestamp":1760503037000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2571-841X\/8\/4\/203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,13]]},"references-count":14,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["reports8040203"],"URL":"https:\/\/doi.org\/10.3390\/reports8040203","relation":{},"ISSN":["2571-841X"],"issn-type":[{"type":"electronic","value":"2571-841X"}],"subject":[],"published":{"date-parts":[[2025,10,13]]}}}