{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T15:17:25Z","timestamp":1771255045653,"version":"3.50.1"},"reference-count":21,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:00:00Z","timestamp":1771027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2019s NextGenerationEU","award":["BG-RRP-2.004-0009-C02"],"award-info":[{"award-number":["BG-RRP-2.004-0009-C02"]}]},{"name":"The Medical University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>Background and Clinical Significance: Prostatic malignancies are amongst the leading malignancies in incidence. They represent a mixed group of conditions, predominantly characterized by adenocarcinomas, which are themselves predominantly acinar. Case Presentation: Herein, we present a morphological case report of a 73-year-old male who underwent transrectal ultrasound-guided needle biopsy due to elevated PSA levels (18.61 ng\/mL). Histopathology of the biopsy specimen was represented by pleomorphic cells with predominantly clear cytoplasm, with relatively eccentric, pyknotically appearing nuclei with hyperchromatic chromatin and no visible nucleoli. After imaging excluded concomitant renal malignancy and confirmatory immunohistochemistry was carried out, the patient was diagnosed with renal-type clear cell carcinoma of the prostate. Conclusions: While unrecognized by the WHO due to its rarity, renal-type clear cell acinar adenocarcinoma of the prostate is a unique type of prostatic malignancy, which, due to its morphological appearance, necessitated careful differential diagnosis.<\/jats:p>","DOI":"10.3390\/reports9010063","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T14:09:54Z","timestamp":1771250994000},"page":"63","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Renal-Type Clear Cell Carcinoma of the Prostate: A Histopathological Case Report of a Rare and Underrecognized Variant"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6950-0615","authenticated-orcid":false,"given":"George","family":"Stoyanov","sequence":"first","affiliation":[{"name":"Department of Pathology, Multiptofile Hospital for Active Treatment, 9700 Shument, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dobri","family":"Marchev","sequence":"additional","affiliation":[{"name":"Department of Urology, Multiptofile Hospital for Active Treatment, 9700 Shument, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Pavlov","sequence":"additional","affiliation":[{"name":"Department of Pathology, Complex Oncology Center, 9700 Shumen, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hristo","family":"Popov","sequence":"additional","affiliation":[{"name":"Department of General and Clinical Pathology, Forensic Medicine and Deontology, Medical University\u2014Varna, 9000 Varna, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,14]]},"reference":[{"key":"ref_1","first-page":"229","article-title":"Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J. 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Urol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.humpath.2022.06.004","article-title":"Morphologic spectrum of treatment-related changes in prostate tissue and prostate cancer: An updated review","volume":"127","author":"Collins","year":"2022","journal-title":"Hum. 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