{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T11:02:12Z","timestamp":1774868532158,"version":"3.50.1"},"reference-count":12,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Eurosets s.r.l."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>Background: Extracorporeal membrane oxygenation (ECMO) is commonly used for temporary support in patients with severe cardiogenic shock and may serve as a bridge to heart transplantation. In recent years, outcomes have improved with better timing, patient management and advances in ECMO technology. Case presentation: We describe the case of a 61-year-old man who developed refractory cardiogenic shock after an extensive acute myocardial infarction complicated by recurrent ventricular arrhythmias. After an initial period of stabilization following complex percutaneous coronary intervention, the patient suddenly deteriorated with acute pulmonary edema and severe hypoxemia. A peripheral femoro-femoral veno-arterial ECMO with distal limb perfusion was promptly implanted using the ECMOLIFE system and the Landing Advance system (Eurosets s.r.l., Medolla, MO, Italy) to stabilize the patient and enable continuous monitoring. Due to severe left ventricular distension, surgical left ventricular venting was performed through a minimally invasive approach. ECMO support allowed rapid hemodynamic stabilization without major complications. During ECMO support, the patient remained stable and after less than 48 h a suitable donor heart became available. The patient was safely transferred to a transplant center while on ECMO and successfully underwent heart transplantation. Conclusions: This case shows that early ECMO implantation, combined with appropriate ventricular unloading and careful management with an advanced monitoring system, can be an optimal support as a bridge to heart transplantation. Limiting the duration of ECMO support and ensuring timely referral to a transplant center may improve outcomes in patients with refractory cardiogenic shock.<\/jats:p>","DOI":"10.3390\/reports9020105","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T09:57:11Z","timestamp":1774864631000},"page":"105","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["ECMO Before Heart Transplantation: Early Implantation and Optimized Assistance with the Eurosets ECMOLIFE System and Landing Advance\u2014A Case Report"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4913-9834","authenticated-orcid":false,"given":"Giuseppe","family":"Santarpino","sequence":"first","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy"},{"name":"Department of Cardiac Surgery, Citt\u00e0 di Lecce Hospital, 73100 Lecce, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2842-4350","authenticated-orcid":false,"given":"Alessandro","family":"Fiorentino","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Citt\u00e0 di Lecce Hospital, 73100 Lecce, Italy"},{"name":"PhD Program \u201cLife Sciences and Technologies\u201d, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3013-7419","authenticated-orcid":false,"given":"Federico","family":"Cucci","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Citt\u00e0 di Lecce Hospital, 73100 Lecce, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1711-043X","authenticated-orcid":false,"given":"Veronica","family":"D\u2019Anna","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Citt\u00e0 di Lecce Hospital, 73100 Lecce, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Speziale","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Citt\u00e0 di Lecce Hospital, 73100 Lecce, Italy"},{"name":"Department of Cardiac Surgery, Santa Maria Hospital GVM Care & Research, 70124 Bari, Italy"},{"name":"Department of Health and Life Sciences, European University of Rome, 00163 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Kim, S.T., Xia, Y., Tran, Z., Hadaya, J., Dobaria, V., Choi, C.W., and Benharash, P. 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Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e032288","DOI":"10.1161\/JAHA.123.032288","article-title":"Timing of Initiation of Extracorporeal Membrane Oxygenation Support and Outcomes Among Patients with Cardiogenic Shock","volume":"13","author":"Jentzer","year":"2024","journal-title":"J. Am. Heart Assoc."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.athoracsur.2020.08.041","article-title":"Evaluation of extracorporeal membrane oxygenation therapy as a bridging method","volume":"112","author":"Lui","year":"2021","journal-title":"Ann. Thorac. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.cardfail.2022.11.011","article-title":"Extracorporeal membrane oxygenation for graft dysfunction early after heart transplantation: A systematic review and meta-analysis","volume":"29","author":"Aleksova","year":"2023","journal-title":"J. Card. Fail."}],"container-title":["Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2571-841X\/9\/2\/105\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:11:25Z","timestamp":1774865485000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2571-841X\/9\/2\/105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,28]]},"references-count":12,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["reports9020105"],"URL":"https:\/\/doi.org\/10.3390\/reports9020105","relation":{},"ISSN":["2571-841X"],"issn-type":[{"value":"2571-841X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,28]]}}}