{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T13:55:28Z","timestamp":1776779728729,"version":"3.51.2"},"reference-count":8,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reports"],"abstract":"<jats:p>Background and Clinical Significance: Intrapericardial ectopic thyroid tissue is extremely rare and can mimic vascular mediastinal or cardiac lesions. Case Presentation: We describe a 62-year-old woman with dyspnea, palpitations, and flushing for several months, progressively worsening, associated with nonspecific ST-segment abnormalities on ECG. Contrast-enhanced CT revealed a small, highly vascularized epicardial mass anterior to the ascending aorta. 18F-FDG PET\/TC findings were inconclusive, and biopsy was not feasible due to the anatomical location. Surgical excision via upper ministernotomy was performed, leading to resolution of symptoms. Histology confirmed benign ectopic thyroid tissue. Conclusions: With fewer than ten similar intrapericardial cases reported in the English-language medical literature, this presentation underlines the diagnostic difficulty of such lesions and the importance of including ectopic thyroid tissue among the less common differential diagnostic considerations for intrapericardial masses, particularly in patients with prior thyroid disease.<\/jats:p>","DOI":"10.3390\/reports9020127","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T11:42:45Z","timestamp":1776771765000},"page":"127","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Peculiar Presentation of an Intrapericardial Ectopic Thyroid"],"prefix":"10.3390","volume":"9","author":[{"given":"Stefano","family":"Auriemma","sequence":"first","affiliation":[{"name":"Department for Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1263-2235","authenticated-orcid":false,"given":"Riccardo","family":"Gherli","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Division, SS Antonio Biagio e Cesare Arrigo Hospital, 15121 Alessandria, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Giacometti","sequence":"additional","affiliation":[{"name":"Pathological Anatomy Division, SS Antonio Biagio e Cesare Arrigo Hospital, 15121 Alessandria, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2484-0963","authenticated-orcid":false,"given":"Annalisa","family":"Roveta","sequence":"additional","affiliation":[{"name":"Research and Innovation Department, SS Antonio Biagio e Cesare Arrigo Hospital, 15121 Alessandria, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4924-9917","authenticated-orcid":false,"given":"Pietro","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Department for Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, Italy"},{"name":"Cardiac Surgery Division, SS Antonio Biagio e Cesare Arrigo Hospital, 15121 Alessandria, Italy"},{"name":"Pathological Anatomy Division, SS Antonio Biagio e Cesare Arrigo Hospital, 15121 Alessandria, Italy"},{"name":"Research and Innovation Department, SS Antonio Biagio e Cesare Arrigo Hospital, 15121 Alessandria, Italy"},{"name":"Thoracic Surgery Division, SS Antonio Biagio e Cesare Arrigo Hospital, 15121 Alessandria, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.14310\/horm.2002.1317","article-title":"Ectopic thyroid: Etiology, pathology and management","volume":"10","author":"Ibrahim","year":"2011","journal-title":"Hormones"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"72","DOI":"10.5761\/atcs.cr.19-00154","article-title":"Intrapericardial Ectopic Goiter: A Very Unusual Presentation","volume":"28","author":"Sato","year":"2022","journal-title":"Ann. Thorac. Cardiovasc. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/0002-9149(86)90871-4","article-title":"Aberrant thyroid gland attached to ascending aorta","volume":"57","author":"Taylor","year":"1986","journal-title":"Am. J. Cardiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1016\/j.ijcard.2011.10.109","article-title":"Intrapericardial ectopic thyroid gland mimicking cardiac tumor","volume":"158","author":"Gackowski","year":"2012","journal-title":"Int. J. Cardiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/icvts\/ivw097","article-title":"Intrapericardial left-sided ectopic thyroid mass supplied by the left circumflex artery","volume":"23","author":"Schneider","year":"2016","journal-title":"Interact. Cardiovasc. Thorac. Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/s00595-006-3439-7","article-title":"Ectopic thyroid gland on the ascending aorta with a partial pericardial defect","volume":"37","author":"Ozpolat","year":"2007","journal-title":"Surg. Today"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/BF02718256","article-title":"The role of surgery in diagnosis and treatment of mediastinal malignancies","volume":"168","author":"Neef","year":"1990","journal-title":"Lung"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1097\/01.MLG.0000163098.01398.79","article-title":"18F-fluorodeoxyglucose uptake in thyroid from positron emission tomogram (PET) for evaluation in cancer patients: High prevalence of malignancy in thyroid PET incidentaloma","volume":"115","author":"Kim","year":"2005","journal-title":"Laryngoscope"}],"container-title":["Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2571-841X\/9\/2\/127\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T12:46:43Z","timestamp":1776775603000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2571-841X\/9\/2\/127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,21]]},"references-count":8,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["reports9020127"],"URL":"https:\/\/doi.org\/10.3390\/reports9020127","relation":{},"ISSN":["2571-841X"],"issn-type":[{"value":"2571-841X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,21]]}}}