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This review discusses the use of modified bases as a means of enhancing serum stability and producing effective therapeutic tools, as well as functionalising these nucleic acids to be used as potential diagnostic agents.<\/jats:p>","DOI":"10.3390\/s131013624","type":"journal-article","created":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T14:11:12Z","timestamp":1381414272000},"page":"13624-13637","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":117,"title":["Aptamers as Theranostic Agents: Modifications, Serum Stability and Functionalisation"],"prefix":"10.3390","volume":"13","author":[{"given":"Sarah","family":"Shigdar","sequence":"first","affiliation":[{"name":"School of Medicine, Deakin University, Pigdons Road, Waurn Ponds, Victoria 3217, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Macdonald","sequence":"additional","affiliation":[{"name":"School of Medicine, 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