{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:16:30Z","timestamp":1790266590567,"version":"4.1.0"},"reference-count":49,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2018,4,27]],"date-time":"2018-04-27T00:00:00Z","timestamp":1524787200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In this work an application of optical fiber sensors for real-time optical monitoring of electrochemical deposition of ketoprofen during its anodic oxidation is discussed. The sensors were fabricated by reactive magnetron sputtering of indium tin oxide (ITO) on a 2.5 cm-long core of polymer-clad silica fibers. ITO tuned in optical properties and thickness allows for achieving a lossy-mode resonance (LMR) phenomenon and it can be simultaneously applied as an electrode in an electrochemical setup. The ITO-LMR electrode allows for optical monitoring of changes occurring at the electrode during electrochemical processing. The studies have shown that the ITO-LMR sensor\u2019s spectral response strongly depends on electrochemical modification of its surface by ketoprofen. The effect can be applied for real-time detection of ketoprofen. The obtained sensitivities reached over 1400 nm\/M (nm\u00b7mg\u22121\u00b7L) and 16,400 a.u.\/M (a.u.\u00b7mg\u22121\u00b7L) for resonance wavelength and transmission shifts, respectively. The proposed method is a valuable alternative for the analysis of ketoprofen within the concentration range of 0.25\u2013250 \u03bcg mL\u22121, and allows for its determination at therapeutic and toxic levels. The proposed novel sensing approach provides a promising strategy for both optical and electrochemical detection of electrochemical modifications of ITO or its surface by various compounds.<\/jats:p>","DOI":"10.3390\/s18051361","type":"journal-article","created":{"date-parts":[[2018,4,27]],"date-time":"2018-04-27T12:04:50Z","timestamp":1524830690000},"page":"1361","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Optical Detection of Ketoprofen by Its Electropolymerization on an Indium Tin Oxide-Coated Optical Fiber Probe"],"prefix":"10.3390","volume":"18","author":[{"given":"Robert","family":"Bogdanowicz","sequence":"first","affiliation":[{"name":"Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, Narutowicza 11\/12, 80-233 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8197-6333","authenticated-orcid":false,"given":"Pawe\u0142","family":"Niedzia\u0142kowski","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Sobaszek","sequence":"additional","affiliation":[{"name":"Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, Narutowicza 11\/12, 80-233 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0698-9211","authenticated-orcid":false,"given":"Dariusz","family":"Burnat","sequence":"additional","affiliation":[{"name":"Institute of Microelectronics and Optoelectronics, Warsaw University of Technology, Koszykowa 75, 00-662 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wioleta","family":"Bia\u0142obrzeska","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zofia","family":"Cebula","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Sezemsky","sequence":"additional","affiliation":[{"name":"Institute of Physics and Biophysics, Faculty of Science, University of South Bohemia, Branisovska 1760, 370 05 Ceske Budejovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Koba","sequence":"additional","affiliation":[{"name":"Institute of Microelectronics and Optoelectronics, Warsaw University of Technology, Koszykowa 75, 00-662 Warszawa, Poland"},{"name":"National Institute of Telecommunications, Szachowa 1, 04-894 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitezslav","family":"Stranak","sequence":"additional","affiliation":[{"name":"Institute of Physics and Biophysics, Faculty of Science, University of South Bohemia, Branisovska 1760, 370 05 Ceske Budejovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadeusz","family":"Ossowski","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateusz","family":"\u015amietana","sequence":"additional","affiliation":[{"name":"Institute of Microelectronics and Optoelectronics, Warsaw University of Technology, Koszykowa 75, 00-662 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,4,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.5650\/jos.59.667","article-title":"Anti-inflammatory and Analgesic Effects of Ketoprofen in Palm Oil Esters Nanoemulsion","volume":"59","author":"Sakeena","year":"2010","journal-title":"J. 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