{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:28:52Z","timestamp":1787840932386,"version":"build-2784847793"},"reference-count":42,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T00:00:00Z","timestamp":1626825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Mobile health (mHealth) has emerged as a potential solution to providing valuable ecological information about the severity and burden of Parkinson\u2019s disease (PD) symptoms in real-life conditions. Objective: The objective of our study was to explore the feasibility and usability of an mHealth system for continuous and objective real-life measures of patients\u2019 health and functional mobility, in unsupervised settings. Methods: Patients with a clinical diagnosis of PD, who were able to walk unassisted, and had an Android smartphone were included. Patients were asked to answer a daily survey, to perform three weekly active tests, and to perform a monthly in-person clinical assessment. Feasibility and usability were explored as primary and secondary outcomes. An exploratory analysis was performed to investigate the correlation between data from the mKinetikos app and clinical assessments. Results: Seventeen participants (85%) completed the study. Sixteen participants (94.1%) showed a medium-to-high level of compliance with the mKinetikos system. A 6-point drop in the total score of the Post-Study System Usability Questionnaire was observed. Conclusions: Our results support the feasibility of the mKinetikos system for continuous and objective real-life measures of a patient\u2019s health and functional mobility. The observed correlations of mKinetikos metrics with clinical data seem to suggest that this mHealth solution is a promising tool to support clinical decisions.<\/jats:p>","DOI":"10.3390\/s21154972","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T22:37:14Z","timestamp":1626993434000},"page":"4972","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Feasibility of a Mobile-Based System for Unsupervised Monitoring in Parkinson\u2019s Disease"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3756-2763","authenticated-orcid":false,"given":"Raquel","family":"Bou\u00e7a-Machado","sequence":"first","affiliation":[{"name":"Instituto de Medicina Molecular, 1649-028 Lisbon, Portugal"},{"name":"CNS\u2014Campus Neurol\u00f3gico, 2560-280 Torres Vedras, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipa","family":"Pona-Ferreira","sequence":"additional","affiliation":[{"name":"CNS\u2014Campus Neurol\u00f3gico, 2560-280 Torres Vedras, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2368-9360","authenticated-orcid":false,"given":"Mariana","family":"Leit\u00e3o","sequence":"additional","affiliation":[{"name":"CNS\u2014Campus Neurol\u00f3gico, 2560-280 Torres Vedras, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Clemente","sequence":"additional","affiliation":[{"name":"Kinetikos, 3030-199 Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diogo","family":"Vila-Vi\u00e7osa","sequence":"additional","affiliation":[{"name":"Kinetikos, 3030-199 Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8463-5625","authenticated-orcid":false,"given":"Linda Azevedo","family":"Kauppila","sequence":"additional","affiliation":[{"name":"CNS\u2014Campus Neurol\u00f3gico, 2560-280 Torres Vedras, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui M.","family":"Costa","sequence":"additional","affiliation":[{"name":"Champalimaud Research, Champalimaud Centre for the Unknown, 1400 Lisbon, Portugal"},{"name":"Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1785-2640","authenticated-orcid":false,"given":"Ricardo","family":"Matias","sequence":"additional","affiliation":[{"name":"Champalimaud Research, Champalimaud Centre for the Unknown, 1400 Lisbon, Portugal"},{"name":"Champalimaud Clinical Centre, Champalimaud Centre for the Unknown, 1400 Lisbon, Portugal"},{"name":"Human Movement Analysis Lab., Escola Superior Sa\u00fade\u2014Instituto Polit\u00e9cnico de Set\u00fabal, 2910-761 Setubal, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim J.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Molecular, 1649-028 Lisbon, Portugal"},{"name":"CNS\u2014Campus Neurol\u00f3gico, 2560-280 Torres Vedras, Portugal"},{"name":"Laboratory of Clinical Pharmacology and Therapeutics, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S219","DOI":"10.1016\/S1353-8020(09)70819-3","article-title":"Multidisciplinary care for patients with Parkinson\u2019s disease","volume":"15","author":"Kalf","year":"2009","journal-title":"Park. 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