{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T02:24:51Z","timestamp":1787883891437,"version":"build-2784847793"},"reference-count":53,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T00:00:00Z","timestamp":1635120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The aim of the study was to evaluate the temperature parameter of the breast area in patients undergoing radiotherapy at various intervals. The relationship between temperature changes on the patient\u2019s skin and the time after the end of radiotherapy was studied. Measurements with a thermal imaging camera were performed in a group of twelve volunteers. Six of them were healthy women who did not have thermal asymmetry between the breasts, whereas six were diagnosed with breast cancer and underwent mastectomy due to the advanced stage of the disease. The patients were qualified for radiation therapy. Thermographic examinations were performed before treatment, two months later and then six months after the end of the treatment. Temperature differences between the healthy breasts and the treated areas were assessed. Additionally, the correlation between a patient\u2019s skin temperature changes and the time after the end of radiotherapy was analyzed. The highest skin temperature increase (1.47 \u00b0C) was observed 6 months after the end of RT compared to the measurement before treatment. It seems that thermovision may bring a new tool for quantitative analyses of the temperature effects of radiotherapy.<\/jats:p>","DOI":"10.3390\/s21217068","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T21:42:05Z","timestamp":1635198125000},"page":"7068","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Use of Thermal Imaging in the Evaluation of Temperature Effects of Radiotherapy in Patients after Mastectomy\u2014First Study"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1317-4486","authenticated-orcid":false,"given":"Agnieszka","family":"Baic","sequence":"first","affiliation":[{"name":"Department of Medical Physics, A. Che\u0142kowski Institute of Physics, University of Silesia, 75 Pu\u0142ku Piechoty 1A St., 41-500 Chorz\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5469-9572","authenticated-orcid":false,"given":"Dominika","family":"Plaza","sequence":"additional","affiliation":[{"name":"Radiotherapy Planning Department, Maria Sk\u0142odowska\u2014Curie National Research Institute of Oncology Gliwice Branch, Wybrzeze Armii Krajowej Street 15, 44-102 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Lange","sequence":"additional","affiliation":[{"name":"Radiotherapy Planning Department, Maria Sk\u0142odowska\u2014Curie National Research Institute of Oncology Gliwice Branch, Wybrzeze Armii Krajowej Street 15, 44-102 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Reudelsdorf-Ullmann","sequence":"additional","affiliation":[{"name":"Radiotherapy Planning Department, Maria Sk\u0142odowska\u2014Curie National Research Institute of Oncology Gliwice Branch, Wybrzeze Armii Krajowej Street 15, 44-102 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0141ukasz","family":"Michalecki","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University Clinical Center of the Medical University of Silesia, Medyk\u00f3w 14 St., 40-572 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6939-9898","authenticated-orcid":false,"given":"Agata","family":"Stanek","sequence":"additional","affiliation":[{"name":"Department and Clinic of Internal Medicine, Angiology and Physical Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Batorego 15 St., 41-902 Bytom, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"\u015alosarek","sequence":"additional","affiliation":[{"name":"Radiotherapy Planning Department, Maria Sk\u0142odowska\u2014Curie National Research Institute of Oncology Gliwice Branch, Wybrzeze Armii Krajowej Street 15, 44-102 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armand","family":"Cholewka","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, A. 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Health Sport"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"465","DOI":"10.2214\/ajr.143.3.465","article-title":"\u201cEarly\u201d breast cancer detection using techniques other than mammography","volume":"143","author":"Kopans","year":"1984","journal-title":"AJR"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.ijthermalsci.2008.06.015","article-title":"A review of thermography as promising non-invasive detection modality for breast tumor","volume":"48","author":"Ng","year":"2009","journal-title":"Int. J. Therm. Sci."},{"key":"ref_4","first-page":"269","article-title":"Does infrared thermography truly have a role in present day breast cancer management?","volume":"107","author":"Amalric","year":"1982","journal-title":"Biomed. Thermolo."},{"key":"ref_5","unstructured":"Parsons, C.A. (1983). Thermography of the female breast. Diagnosis of Breast Disease, University Park Press."},{"key":"ref_6","unstructured":"Head, J., Lipari, C., and Elliott, R. (1999, January 13\u201316).  Comparison of Mammography and Breast Infrared Imaging: Sensitivity, Specificity, False Negatives, False Positives, Positive Predictive Value and Negative Predictive Value. Proceedings of the First Joint BMES\/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. No.99CH37015), Atlanta, GA, USA."},{"key":"ref_7","unstructured":"\u015aniadecki, M. (2015). Kryteria Rozpoznawania I Wczesne Objawy Chor\u00f3b Nowotworowych, Via Medica."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1007\/s10973-017-6141-7","article-title":"How to use thermal imaging in venous insufficiency?","volume":"130","author":"Cholewka","year":"2017","journal-title":"J. Therm. Anal. Calorim."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s10973-010-0873-y","article-title":"Thermovision diagnostics in chosen spine diseases treated by whole body cryotherapy","volume":"102","author":"Cholewka","year":"2010","journal-title":"J. Therm. Anal. Calorim."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.pdpdt.2012.07.001","article-title":"Does the temperature gradient correlate with the photodynamic diagnosis parameter numerical colour value (NCV)?","volume":"10","author":"Cholewka","year":"2013","journal-title":"Photodiagn. Photodyn. Ther."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1007\/s10973-013-3356-0","article-title":"Thermal imaging application in chronic venous disease","volume":"115","author":"Cholewka","year":"2013","journal-title":"J. Therm. Anal. Calorim."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Kajewska, J., Cholewka, A., Paj\u0105k, J., and Stanek, A. (2016, January 4\u20138). The Thermal Imaging Parameters in Correlation with USG Duplex Parameters used in Chronic Venous Disease of Lower Extremities Diagnosis. Proceedings of the 2016 Quantitative InfraRed Thermography Conference, Gdansk, Poland.","DOI":"10.21611\/qirt.2016.049"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S0140-6736(95)92774-3","article-title":"Angiogenesis and breast cancer metastasis","volume":"346","author":"Ellis","year":"1995","journal-title":"Lancet"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1046\/j.1524-4741.1998.440245.x","article-title":"Infrared imaging of the breast: Initial reappraisal using high-resolution digital technology in 100 successive cases of stage I and II breast cancer","volume":"4","author":"Keyserlingk","year":"1998","journal-title":"Breast J."},{"key":"ref_15","unstructured":"Chmielewski, L., Kulikowski, L.J., and Nowakowski, A. (2003). Obrazowanie Biomedyczne, Akademicka Oficyna Wydawnicza EXIT."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S0002-9610(05)80017-0","article-title":"Nitric oxide: An overview","volume":"170","author":"Rodeberg","year":"1995","journal-title":"Am. J. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1158\/1078-0432.CCR-05-1269","article-title":"Nitric oxide in breast cancer: Induction of vascular endothelial growth factor-C and correlation with metastasis and poor prognosis","volume":"12","author":"Nakamura","year":"2006","journal-title":"Clin. Cancer Res."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0304-3835(94)90354-9","article-title":"Hyperthermia of the cancerous breast: Analysis of mechanism","volume":"84","author":"Anbar","year":"1994","journal-title":"Cancer Lett."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/bcr1796","article-title":"Breast tumour angiogenesis","volume":"9","author":"Fox","year":"2007","journal-title":"Breast Cancer Res."},{"key":"ref_20","first-page":"2679","article-title":"Quantitative visualization and detection of skin cancer using dynamic thermal imaging","volume":"51","author":"Herman","year":"2011","journal-title":"J. Vis. Exp."},{"key":"ref_21","unstructured":"Gamagami, P. (1986). Atlas of Mammography: New Early Signs in Breast Cancer, Blackwell Science."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1749-6632.1993.tb17203.x","article-title":"Breast thermography is a noninvasive prognostic procedure that predicts tumor growth rate in breast cancer patients","volume":"698","author":"Head","year":"1993","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1080\/03091900110043621","article-title":"Numerical computation as a tool to aid thermographic interpretation","volume":"25","author":"Ng","year":"2001","journal-title":"J. Med. Eng. Technol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1177\/1534735408326171","article-title":"A comparative review of thermography as a breast cancer screening technique","volume":"8","author":"Kennedy","year":"2009","journal-title":"Integr. Cancer Ther."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1109\/51.687959","article-title":"Progress in the measurement of human body temperature","volume":"17","author":"Ring","year":"1998","journal-title":"IEEE Eng. Med. Biol. Mag."},{"key":"ref_26","first-page":"7","article-title":"The technique of infrared imaging in medicine","volume":"10","author":"Ring","year":"2000","journal-title":"Thermol. Int."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"R33","DOI":"10.1088\/0967-3334\/33\/3\/R33","article-title":"Infrared thermal imaging in medicine","volume":"33","author":"Ring","year":"2012","journal-title":"Physiol. Meas."},{"key":"ref_28","first-page":"125","article-title":"The Glamorgan Protocol for recording and evaluation of thermal images of the human body","volume":"18","author":"Ammer","year":"2008","journal-title":"Thermol. Int."},{"key":"ref_29","unstructured":"Ammer, K., and Ring, E.F.J. (1995). The Thermal Image in Medicine and Biology, Uhlen-Verlag."},{"key":"ref_30","first-page":"121","article-title":"Thermovision and its applications in medicine","volume":"3","author":"Bauer","year":"1997","journal-title":"Acta Bio. Opt. Inf. Med."},{"key":"ref_31","first-page":"18","article-title":"Current indications and methods of postoperative radiation therapy\u2014Repetition before the exam","volume":"12","year":"2016","journal-title":"Oncol. Clin. Pract."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.ejon.2014.04.009","article-title":"Retrospective study of radiotherapy-induced skin reactions in breast cancer patients: Reduced incidence of moist desquamation with a hydroactive colloid gel versus dexpanthenol","volume":"18","author":"Censabella","year":"2014","journal-title":"Eur. J. Oncol. Nurs."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.radonc.2016.09.019","article-title":"Evaluation of acute skin toxicity in breast radiotherapy with a new quantitative approach","volume":"122","author":"Sanchis","year":"2017","journal-title":"Radiother. Oncol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/01.SMJ.0000140866.97278.87","article-title":"Skin toxicity during breast irradiation: Pathophysiology and management","volume":"97","author":"Harper","year":"2004","journal-title":"South. Med. J."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jaad.2005.08.054","article-title":"Radiation dermatitis: Clinical presentation. pathophysiology and treatment 2006","volume":"54","author":"Hymes","year":"2006","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.canrad.2017.10.007","article-title":"Evaluation of acute skin toxicity of breast radiotherapy using thermography: Results of a prospective single-centre trial","volume":"22","author":"Maillot","year":"2017","journal-title":"Cancer Radiother."},{"key":"ref_37","first-page":"989","article-title":"An automated method for the evaluation of breast cancer using infrared thermography","volume":"17","author":"Guevara","year":"2018","journal-title":"EXCLI J."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3233\/BD-160236","article-title":"Evaluation of efficacy of thermographic breast imaging in breast cancer: A pilot study","volume":"36","author":"Prasada","year":"2016","journal-title":"Breast Dis."},{"key":"ref_39","first-page":"345","article-title":"Zastosowanie obrazowania termicznego w diagnostyce nowotwor\u00f3w piersi","volume":"7","author":"Baic","year":"2018","journal-title":"In\u017c. Fiz. Med."},{"key":"ref_40","first-page":"277","article-title":"Zastosowanie obrazowania termicznego w ocenie efekt\u00f3w radioterapii u pacjentek po mastektomii","volume":"9","author":"Plaza","year":"2020","journal-title":"In\u017c. Fiz. Med."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s10549-006-9480-9","article-title":"Predictive factors for late normal tissue complications following radiotherapy for breast cancer","volume":"106","author":"Lilla","year":"2007","journal-title":"Breast Cancer Res. Treat."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Plaza, D., Baic, A., Lange, B., Stanek, A., \u015alosarek, K., Kowalczyk, A., and Cholewka, A. (2021). Correlation between isotherms and isodoses in breast cancer radiotherapy\u2014First study. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18020619"},{"key":"ref_43","first-page":"124","article-title":"Phase 2 study of silver leaf dressing for treatment of radiation-induced dermatitis in patients receiving radiotherapy to the head and neck","volume":"37","author":"Vavassis","year":"2008","journal-title":"J. Otolaryngol. Head Neck Surg."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"213","DOI":"10.4103\/0378-6323.32755","article-title":"Topical betamethasone for prevention of radiation dermatitis","volume":"73","author":"Omidvari","year":"2007","journal-title":"Indian J. Dermatol. Venereol. Leprol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1200\/JCO.2004.10.911","article-title":"The need for adverse effects reporting standards in oncology clinical trials","volume":"22","author":"Trotti","year":"2004","journal-title":"J. Clin. Oncol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/pon.1734","article-title":"A qualitative analysis of acute skin toxicity among breast cancer radiotherapy patients","volume":"20","author":"Schnur","year":"2011","journal-title":"Psycho Oncol."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Chen, M.-F., Chen, W.-C., Lai, C.-H., Hung, C.-H., Liu, K.-C., and Cheng, Y.-H. (2010). Predictive factors of radiation-induced skin toxicity in breast cancer patients. BMC Cancer, 10.","DOI":"10.1186\/1471-2407-10-508"},{"key":"ref_48","unstructured":"(2013). PN-EN ISO 80601-2-56: English Version, Catalog of Polish Standards, Polish Committee for Standardization."},{"key":"ref_49","unstructured":"(2010). PN-EN ISO 80601-2-59: English Version, Catalog of Polish Standards, Polish Committee for Standardization."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3109\/03091901003663836","article-title":"New standards for devices used for the measurement of human body temperature","volume":"34","author":"Ring","year":"2010","journal-title":"J. Med. Eng. Technol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.breast.2015.01.008","article-title":"RTOG, CTCAE and WHO criteria for acute radiation dermatitis correlate with cutaneous blood flow measurements","volume":"24","author":"Chuang","year":"2015","journal-title":"Breast"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"e357","DOI":"10.1016\/j.ijrobp.2012.05.009","article-title":"Re-examining the evidence in radiation dermatitis management literature: An overview and a critical appraisal of systematic reviews","volume":"84","author":"Chan","year":"2012","journal-title":"Int. J. Radiat. Oncol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1080\/02656736.2019.1685685","article-title":"Relationships between the changes of skin temperature and radiation skin injury","volume":"36","author":"Zhu","year":"2019","journal-title":"Int. J. Hyperth."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/21\/21\/7068\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:23:02Z","timestamp":1760167382000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/21\/21\/7068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,25]]},"references-count":53,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2021,11]]}},"alternative-id":["s21217068"],"URL":"https:\/\/doi.org\/10.3390\/s21217068","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,25]]}}}