{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:20:16Z","timestamp":1790317216049,"version":"4.1.0"},"reference-count":38,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T00:00:00Z","timestamp":1686700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Leg ulcers are a very serious worldwide medical problem. When the ulcer is extensive and deep the prognosis is usually unfavorable. The treatment requires comprehensive solutions that take into account modern specialized medical dressings, and more and more often, selected methods in the field of physical medicine. The study included 30 patients (13 women\u201443.4% and 17 men\u201456.6%) with chronic arterial ulcers of the lower limbs. The mean age of the treated patients was 65.63 \u00b1 8.77 years. Patients were randomly assigned to two study groups. In group 1 (16 patients), specialist ATRAUMAN Ag medical dressings and local hyperbaric oxygen therapy treatments were used. In group 2 (14 patients), only specialized ATRAUMAN Ag dressings were used. The treatment was carried out for 4 weeks. The progress of healing ulcers was assessed by using the planimetric method, while the intensity of pain ailments was assessed by the visual analog VAS scale. In both study groups, a statistically significant reduction in the mean surface area of the treated ulcers was obtained, respectively, from 8.53 \u00b1 1.71 cm2 to 5.55 \u00b1 1.11 cm2 in group 1 (p &lt; 0.001) and 8.43 \u00b1 1.51 cm2 to 6.28 \u00b1 1.13 cm2 in group 2 (p &lt; 0.001). There was also a statistically significant reduction in the intensity of pain ailments, respectively: 7.93 \u00b1 0.68 points to 5.00 \u00b1 0.63 points in group 1 (p &lt; 0.001) and 8.00 \u00b1 0.67 points to 5.64 \u00b1 0.49 points in group 2 (p &lt; 0.001). The percentage change in ulcer area from baseline in group 1 was 34.6 \u00b1 8.47% and was statistically significantly greater than in group 2 (25.23 \u00b1 6.01%) (p = 0.003). In turn, the percentage assessment of the pain intensity assessed in the VAS scale in group 1 was 36.97 \u00b1 6.36% and was statistically significantly higher compared to group 2 (29.34 \u00b1 4.77%) (p = 0.002). The addition of local hyperbaric oxygen therapy treatments as a supplement to the therapy with the use of specialized medical dressings improves the effectiveness the arterial ulcers treatment of the lower limbs in terms of reducing the ulceration area and reducing pain ailments.<\/jats:p>","DOI":"10.3390\/s23125582","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T02:28:56Z","timestamp":1686796136000},"page":"5582","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Application of Topical Hyperbaric Oxygen Therapy and Medical Active Dressings in the Treatment of Arterial Leg Ulcers\u2014A Pilot Study"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6181-337X","authenticated-orcid":false,"given":"Jaros\u0142aw","family":"Pasek","sequence":"first","affiliation":[{"name":"Collegium Medicum im. dr W\u0142adys\u0142awa Biega\u0144skiego, Jan D\u0142ugosz University in Cz\u0119stochowa, 13\/15 Armii Krajowej St., 42-200 Cz\u0119stochowa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4983-8018","authenticated-orcid":false,"given":"Sebastian","family":"Szajkowski","sequence":"additional","affiliation":[{"name":"Faculty of Medical and Social Sciences, Warsaw Medical Academy of Applied Sciences, 8 Rydygiera St., 01-793 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2210-8744","authenticated-orcid":false,"given":"Grzegorz","family":"Cie\u015blar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Angiology and Physical Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 15 Stefana Batorego St., 41-902 Bytom, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.5114\/lr.2020.99068","article-title":"Arterial ulcers\u2014Clinical picture, diagnostics and conservative treatment","volume":"17","author":"Szewczyk","year":"2020","journal-title":"Leczenie Ran"},{"key":"ref_2","first-page":"1","article-title":"Management consensus of peripheral arterial disease (TASC II)","volume":"13","author":"Norgren","year":"2007","journal-title":"Acta Angiol."},{"key":"ref_3","first-page":"159","article-title":"Chronic wounds: Evaluation and management","volume":"101","author":"Bowers","year":"2020","journal-title":"Am. 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