{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:26:32Z","timestamp":1792157192059,"version":"4.4.0"},"reference-count":49,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union"},{"name":"Horizon Europe grant for project NavigAIt"},{"name":"European Innovation Council"},{"name":"United Kingdom Research and Innovation (UKRI)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The 10-m walk test (10MWT) is a stopwatch-based clinical mobility assessment. To better understand mobility limitations, 10MWT test completion times may be complemented with gait parameters like step length. State-of-the-art augmented reality (AR) glasses can potentially do this given their unique 3D-positional data from which gait parameters may be derived. We examined the test-retest reliability, concurrent validity, and face validity of gait parameters derived from AR glasses during a 10MWT in 20 people with Parkinson\u2019s disease, performed at self-selected comfortable and fast-but-safe walking speeds. AR-derived 10MWT completion times and gait parameters (mean step length, cadence, and maximal gait speed) were compared across repetitions and with lab-based (Interactive Walkway) and clinical (stopwatch) reference systems. Good-to-excellent test-retest reliability statistics were observed for test completion times and gait parameters for all systems and conditions alike. Concurrent validity was demonstrated between AR, lab-based, and clinical references for test completion times (good-to-excellent agreement: ICC &gt; 0.879) and gait parameters (excellent agreement: ICC &gt; 0.942). Face validity was confirmed by significant differences in test completion times and gait parameters between speed conditions in a-priori expected directions. These findings support the conclusion that gait parameters can be derived reliably and validly from AR glasses in people with Parkinson\u2019s disease.<\/jats:p>","DOI":"10.3390\/s25041230","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T03:47:06Z","timestamp":1739850426000},"page":"1230","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Gait Parameters Can Be Derived Reliably and Validly from Augmented Reality Glasses in People with Parkinson\u2019s Disease Performing 10-m Walk Tests at Comfortable and Fast Speeds"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3208-3475","authenticated-orcid":false,"given":"Pieter F.","family":"van Doorn","sequence":"first","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, 1081 BT Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daphne J.","family":"Geerse","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, 1081 BT Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4531-642X","authenticated-orcid":false,"given":"Jara S.","family":"van Bergem","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, 1081 BT Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4554-3628","authenticated-orcid":false,"given":"Eva M.","family":"Hoogendoorn","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, 1081 BT Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9425-5412","authenticated-orcid":false,"suffix":"Jr.","given":"Edward","family":"Nyman","sequence":"additional","affiliation":[{"name":"Strolll Ltd., Stafford ST16 2LP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8534-1124","authenticated-orcid":false,"given":"Melvyn","family":"Roerdink","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, 1081 BT Amsterdam, The Netherlands"},{"name":"Department of Nutrition and Movement Sciences, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands"},{"name":"Department of Nutrition and Movement Sciences, MHeNs Institute of Mental Health and Neurosciences, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e464","DOI":"10.1016\/S2666-7568(24)00094-1","article-title":"Temporal trends in the prevalence of Parkinson\u2019s disease from 1980 to 2023: A systematic review and meta-analysis","volume":"5","author":"Zhu","year":"2024","journal-title":"Lancet Healthy Longev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S1474-4422(19)30044-4","article-title":"Gait impairments in Parkinson\u2019s disease","volume":"18","author":"Mirelman","year":"2019","journal-title":"Lancet Neurol."},{"key":"ref_3","unstructured":"WHO. W.H.O. (2025, January 15). Parkinson Disease. Available online:https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/parkinson-disease."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1123\/japa.2013-0236","article-title":"Walking Speed: The Functional Vital Sign","volume":"23","author":"Middleton","year":"2015","journal-title":"J. Aging Phys. Act."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1002\/mds.26572","article-title":"Measurement instruments to assess posture, gait, and balance in Parkinson\u2019s disease: Critique and recommendations","volume":"31","author":"Bloem","year":"2016","journal-title":"Mov. Disord."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e16599","DOI":"10.1016\/j.heliyon.2023.e16599","article-title":"Mobile and wearable technologies for the analysis of Ten Meter Walk Test: A concise systematic review","volume":"9","author":"Gabriel","year":"2023","journal-title":"Heliyon"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"100222","DOI":"10.1016\/j.array.2022.100222","article-title":"Visual SLAM algorithms and their application for AR, mapping, localization and wayfinding","volume":"15","author":"Theodorou","year":"2022","journal-title":"Array"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Geerse, D.J., Coolen, B., and Roerdink, M. (2020). Quantifying Spatiotemporal Gait Parameters with HoloLens in Healthy Adults and People with Parkinson\u2019s Disease: Test-Retest Reliability, Concurrent Validity, and Face Validity. Sensors, 20.","DOI":"10.3390\/s20113216"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1743-0003-2-23","article-title":"Effect of gait speed on gait rhythmicity in Parkinson\u2019s disease: Variability of stride time and swing time respond differently","volume":"2","author":"Giladi","year":"2005","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.jbiomech.2017.12.002","article-title":"Step length determines minimum toe clearance in older adults and people with Parkinson\u2019s disease","volume":"71","author":"Alcock","year":"2018","journal-title":"J. Biomech."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/00002826-198406000-00008","article-title":"Assessment of Parkinson\u2019s disease","volume":"7","author":"Larsen","year":"1984","journal-title":"Clin. Neuropharmacol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1002\/mds.22340","article-title":"Movement Disorder Society-Sponsored Revision of the Unified Parkinson\u2019s Disease Rating Scale (MDS-UPDRS): Scale Presentation and Clinimetric Testing Results","volume":"23","author":"Goetz","year":"2008","journal-title":"Mov. Disord."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.gaitpost.2009.07.108","article-title":"Reliability of the new freezing of gait questionnaire: Agreement between patients with Parkinson\u2019s disease and their carers","volume":"30","author":"Nieuwboer","year":"2009","journal-title":"Gait Posture"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3109\/03790799009166594","article-title":"Mobility after stroke: Reliability of measures of impairment and disability","volume":"12","author":"Collen","year":"1990","journal-title":"Int. Disabil. Stud."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Geerse, D.J., Coolen, B.H., and Roerdink, M. (2015). Kinematic Validation of a Multi-Kinect v2 Instrumented 10-Meter Walkway for Quantitative Gait Assessments. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0139913"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Geerse, D.J., Roerdink, M., Marinus, J., and Van Hilten, J.J. (2018). Assessing Walking Adaptability in Parkinson\u2019s Disease: \u201cThe Interactive Walkway\u201d. Front. Neurol., 9.","DOI":"10.3389\/fneur.2018.01096"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.medengphy.2016.06.015","article-title":"Concurrent validity of the Microsoft Kinect for Windows v2 for measuring spatiotemporal gait parameters","volume":"38","author":"Dolatabadi","year":"2016","journal-title":"Med. Eng. Phys."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.medengphy.2017.03.007","article-title":"Microsoft Kinect can distinguish differences in over-ground gait between older persons with and without Parkinson\u2019s disease","volume":"44","author":"Eltoukhy","year":"2017","journal-title":"Med. Eng. Phys."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Springer, S., and Yogev Seligmann, G. (2016). Validity of the Kinect for Gait Assessment: A Focused Review. Sensors, 16.","DOI":"10.3390\/s16020194"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.gaitpost.2017.02.021","article-title":"Walking-Adaptability Assessments with the Interactive Walkway: Between-Systems Agreement and Sensitivity to Task and Subject Variations","volume":"54","author":"Geerse","year":"2017","journal-title":"Gait Posture"},{"key":"ref_21","unstructured":"Neumann, D.A. (2010). Kinesiology of walking. Kinesiology of the Musculoskeletal System, Mosby Elsevier, Inc."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Liu, Y.-W. (2012). Hilbert Transform and Applications, InTech.","DOI":"10.5772\/37727"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jcm.2016.02.012","article-title":"A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research","volume":"15","author":"Koo","year":"2016","journal-title":"J. Chiropr. Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/096228029900800204","article-title":"Measuring agreement in method comparison studies","volume":"8","author":"Bland","year":"1999","journal-title":"Stat. Methods Med. Res."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4103\/aca.ACA_157_18","article-title":"Descriptive statistics and normality tests for statistical data","volume":"22","author":"Mishra","year":"2019","journal-title":"Ann. Card. Anaesth."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Girden, E.R. (1992). ANOVA: Repeated Measures, Sage Publications, Inc.","DOI":"10.4135\/9781412983419"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Sun, R., Aldunate, R.G., and Sosnoff, J.J. (2019). The Validity of a Mixed Reality-Based Automated Functional Mobility Assessment. Sensors, 19.","DOI":"10.20944\/preprints201904.0120.v1"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1109\/THMS.2020.3016082","article-title":"The HoloLens Augmented Reality System Provides Valid Measures of Gait Performance in Healthy Adults","volume":"50","author":"Koop","year":"2020","journal-title":"IEEE Trans. Hum. Mach. Syst."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Miller Koop, M., Rosenfeldt, A.B., Owen, K., Penko, A.L., Streicher, M.C., Albright, A., and Alberts, J.L. (2022). The Microsoft HoloLens 2 Provides Accurate Measures of Gait, Turning, and Functional Mobility in Healthy Adults. Sensors, 22.","DOI":"10.3390\/s22052009"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Van Bergem, J.S., Van Doorn, P.F., Hoogendoorn, E.M., Geerse, D.J., and Roerdink, M. (2024). Gait and Balance Assessments with Augmented Reality Glasses in People with Parkinson\u2019s Disease: Concurrent Validity and Test\u2013Retest Reliability. Sensors, 24.","DOI":"10.20944\/preprints202407.0142.v1"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.gaitpost.2018.04.047","article-title":"The use of wearable devices for walking and running gait analysis outside of the lab: A systematic review","volume":"63","author":"Benson","year":"2018","journal-title":"Gait Posture"},{"key":"ref_32","unstructured":"Kirk, C., K\u00fcderle, A., Mic\u00f3-Amigo, M.E., Bonci, T., Paraschiv-Ionescu, A., Ullrich, M., Soltani, A., Gazit, E., Salis, F., and Alcock, L. (2024). Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device. Sci. Rep., 14."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"103970","DOI":"10.1016\/j.archger.2019.103970","article-title":"Are cost-effective technologies feasible to measure gait in older adults? A systematic review of evidence-based literature","volume":"87","author":"Zhong","year":"2020","journal-title":"Arch. Gerontol. Geriatr."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Jakob, V., K\u00fcderle, A., Kluge, F., Klucken, J., Eskofier, B.M., Winkler, J., Winterholler, M., and Gassner, H. (2021). Validation of a Sensor-Based Gait Analysis System with a Gold-Standard Motion Capture System in Patients with Parkinson\u2019s Disease. Sensors, 21.","DOI":"10.3390\/s21227680"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1002\/mds.25628","article-title":"Quantitative wearable sensors for objective assessment of Parkinson\u2019s disease","volume":"28","author":"Maetzler","year":"2013","journal-title":"Mov. Disord."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1177\/15459683231184190","article-title":"A Randomized Clinical Trial to Evaluate a Digital Therapeutic to Enhance Gait Function in Individuals With Parkinson\u2019s Disease","volume":"37","author":"Alberts","year":"2023","journal-title":"Neurorehabilit. Neural Repair"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Alberts, J.L., Kaya, R.D., Scelina, K., Scelina, L., Zimmerman, E.M., Walter, B.L., and Rosenfeldt, A.B. (2022). Digitizing a Therapeutic: Development of an Augmented Reality Dual-Task Training Platform for Parkinson\u2019s Disease. Sensors, 22.","DOI":"10.3390\/s22228756"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.gaitpost.2024.11.007","article-title":"An augmented reality dual-task intervention improves postural stability in individuals with Parkinson\u2019s disease","volume":"115","author":"Rosenfeldt","year":"2025","journal-title":"Gait Posture"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Hardeman, L.E.S., Geerse, D.J., Hoogendoorn, E.M., Nonnekes, J., and Roerdink, M. (2024). Remotely prescribed, monitored, and tailored home-based gait-and-balance exergaming using augmented reality glasses: A clinical feasibility study in people with Parkinson\u2019s disease. Front. Neurol., 15.","DOI":"10.3389\/fneur.2024.1373740"},{"key":"ref_40","unstructured":"Geerse, D.J., Hoogendoorn, E.M., van Doorn, P.F., van Bergem, J.S., van Dam, A.T., Hardeman LE, S., and Roerdink, M. (2024). Cueing-assisted gamified augmented-reality gait-and-balance rehabilitation at home for people with Parkinson\u2019s disease: Protocol of a pragmatic randomized controlled trial implemented in the clinical pathway. Front. Neurol., 16."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"afac175","DOI":"10.1093\/ageing\/afac175","article-title":"Effectiveness of exergaming-based interventions for mobility and balance performance in older adults with Parkinson\u2019s disease: Systematic review and meta-analysis of randomised controlled trials","volume":"51","author":"Zhang","year":"2022","journal-title":"Age Ageing"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Hoogendoorn, E.M., Geerse, D.J., Van Dam, A.T., Stins, J.F., and Roerdink, M. (2024). Gait-modifying effects of augmented-reality cueing in people with Parkinson\u2019s disease. Front. Neurol., 15.","DOI":"10.3389\/fneur.2024.1379243"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.gaitpost.2023.10.008","article-title":"Holographic Hintways: A systems feasibility and usability study of augmented reality cueing for gait adaptation","volume":"107","author":"Retzinger","year":"2024","journal-title":"Gait Posture"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1016\/j.parkreldis.2015.08.031","article-title":"Neurorehabilitation for Parkinson\u2019s disease: Future perspectives for behavioural adaptation","volume":"22","author":"Ekker","year":"2016","journal-title":"Park. Relat. Disord."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"105834","DOI":"10.1016\/j.parkreldis.2023.105834","article-title":"Augmented reality cueing for freezing of gait: Reviewing an emerging therapy","volume":"116","author":"Baugher","year":"2023","journal-title":"Park. Relat. Disord."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Geerse, D.J., Coolen, B., Van Hilten, J.J., and Roerdink, M. (2022). Holocue: A Wearable Holographic Cueing Application for Alleviating Freezing of Gait in Parkinson\u2019s Disease. Front. Neurol., 12.","DOI":"10.3389\/fneur.2021.628388"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1682\/JRRD.2009.10.0165","article-title":"At-home training with closed-loop augmented-reality cueing device for improving gait in patients with Parkinson disease","volume":"47","author":"Espay","year":"2010","journal-title":"J. Rehabil. Res. Dev."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Janssen, S., Bolte, B., Nonnekes, J., Bittner, M., Bloem, B.R., Heida, T., Zhao, Y., and Van Wezel, R.J.A. (2017). Usability of Three-dimensional Augmented Visual Cues Delivered by Smart Glasses on (Freezing of) Gait in Parkinson\u2019s Disease. Front. Neurol., 8.","DOI":"10.3389\/fneur.2017.00279"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0022-510X(03)00104-7","article-title":"Gait dynamics in Parkinson\u2019s disease: Relationship to Parkinsonian Features, Falls and Response to Levodopa","volume":"212","author":"Schaafsma","year":"2003","journal-title":"J. Neurol. Sci."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/25\/4\/1230\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:36:40Z","timestamp":1760027800000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/25\/4\/1230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,18]]},"references-count":49,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["s25041230"],"URL":"https:\/\/doi.org\/10.3390\/s25041230","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,18]]}}}