{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:04:40Z","timestamp":1792116280168,"version":"4.4.0"},"reference-count":49,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Szeged Open Access Fund","award":["8225"],"award-info":[{"award-number":["8225"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Actigraphy quantifies human locomotor activity by measuring wrist acceleration via wearable devices at relatively high rates and converting it into lower-temporal-resolution activity values; however, the computational implementations of this data compression differ substantially across manufacturers. Building on our previous work comparing activity determination methods, we have investigated how they (e.g., digital filtering and data compression) influence nonparametric circadian rhythm analysis and sleep\u2013wake scoring. In addition to our generalized actigraphic framework, we have also emulated the use of specific devices commonly employed in such sleep-related studies by applying their methods to raw actigraphic acceleration data we collected to demonstrate, through concrete real-life examples, how methodological choices may shape analytical outcomes. Additionally, we assessed whether nonparametric indicators could be derived directly from acceleration data without compressing them into activity values. Overall, our analysis revealed that all these analytical approaches to the sleep\u2013wake cycle can be substantially affected by the manufacturer-dependent actigraphic methodology employed, with the observed effects traceable to distinct steps of the signal-processing pipeline, underscoring the necessity of cross-manufacturer harmonization from a clinically oriented perspective.<\/jats:p>","DOI":"10.3390\/s25247659","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T15:53:46Z","timestamp":1765986826000},"page":"7659","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Impact of Quantifying Human Locomotor Activity on Examining Sleep\u2013Wake Cycles"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1867-5861","authenticated-orcid":false,"given":"B\u00e1lint","family":"Macz\u00e1k","sequence":"first","affiliation":[{"name":"Department of Technical Informatics, University of Szeged, 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad\u00e9l Zita","family":"Hord\u00f3s","sequence":"additional","affiliation":[{"name":"Department of Technical Informatics, University of Szeged, 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2720-3380","authenticated-orcid":false,"given":"Gergely","family":"Vadai","sequence":"additional","affiliation":[{"name":"Department of Technical Informatics, University of Szeged, 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/s41746-023-00802-1","article-title":"40 Years of Actigraphy in Sleep Medicine and Current State of the Art Algorithms","volume":"6","author":"Patterson","year":"2023","journal-title":"npj Digit. 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