{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:15:03Z","timestamp":1777367703057,"version":"3.51.4"},"reference-count":23,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The aim of this study was to shed light on activity-based prospective memory performance in children and adult patients with narcolepsy type 1 (NT1) during the first sixty minutes after morning awakening. With reference to the children (C) sample, 21 C-NT1 patients and 20 healthy controls (C-HC) were enrolled; as regards adults (A), 31 A-NT1 patients and 51 A-HC were examined. Each participant used an actigraph for one week, being asked to press the event marker button at get-up time (prospective memory task\u2014PMT). Computing the time interval between the get-up time and the moment the event marker button was pushed, no significant differences were observed in the children\u2019s groups. In contrast, in the adult groups, A-NT1 patients had a longer interval than A-HC. Moreover, the rate of compliant performers (those who remembered to push the event-marker button within 2 min of get-up time) and late performers was significantly different in adults only, with a low rate of compliant performers in A-NT1 patients. In C-NT1, a shorter cognitive inertia was associated with higher motor activity after awakening; in contrast, this association was not observed in A-NT1. Overall, the present pattern of results suggests that prospective memory performance is impaired only in NT1 adult patients.<\/jats:p>","DOI":"10.3390\/s26092681","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:12:31Z","timestamp":1777363951000},"page":"2681","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sensor-Based Assessment of Morning Prospective Memory in Narcolepsy Type 1: Evidence from Children and Adult Cohorts"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6797-9266","authenticated-orcid":false,"given":"Lorenzo","family":"Tonetti","sequence":"first","affiliation":[{"name":"Department of Psychology \u201cRenzo Canestrari\u201d, University of Bologna, 40127 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3252-8083","authenticated-orcid":false,"given":"Sara","family":"Giovagnoli","sequence":"additional","affiliation":[{"name":"Department of Psychology \u201cRenzo Canestrari\u201d, University of Bologna, 40127 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Gnazzo","sequence":"additional","affiliation":[{"name":"Clinic of Child and Adolescent Neuropsychiatry, Department of Mental and Physical Health and Preventive Medicine, University of Campania \u201cLuigi Vanvitelli\u201d, 80138 Naples, Italy"},{"name":"IRCCS Institute of Neurological Sciences of Bologna, 40139 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4149-1331","authenticated-orcid":false,"given":"Miranda","family":"Occhionero","sequence":"additional","affiliation":[{"name":"Department of Psychology \u201cRenzo Canestrari\u201d, University of Bologna, 40127 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Pizza","sequence":"additional","affiliation":[{"name":"IRCCS Institute of Neurological Sciences of Bologna, 40139 Bologna, Italy"},{"name":"Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40139 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Plazzi","sequence":"additional","affiliation":[{"name":"IRCCS Institute of Neurological Sciences of Bologna, 40139 Bologna, Italy"},{"name":"Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8438-7828","authenticated-orcid":false,"given":"Vincenzo","family":"Natale","sequence":"additional","affiliation":[{"name":"Department of Psychology \u201cRenzo Canestrari\u201d, University of Bologna, 40127 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,26]]},"reference":[{"key":"ref_1","unstructured":"American Academy of Sleep Medicine (2023). International Classification of Sleep Disorders\u2014Third Edition, Text Revision (ICSD-3-TR), American Academy of Sleep Medicine."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"zsae150","DOI":"10.1093\/sleep\/zsae150","article-title":"Impaired cognition in narcolepsy: Clinical and neurobiological perspectives","volume":"47","author":"Cano","year":"2024","journal-title":"Sleep"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"zpae043","DOI":"10.1093\/sleepadvances\/zpae043","article-title":"The nature and magnitude of cognitive impairment in narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia: A meta-analysis","volume":"5","author":"Harel","year":"2024","journal-title":"Sleep Adv."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s40263-024-01142-8","article-title":"A Survey of People Living with Narcolepsy in the USA: Path to Diagnosis, Quality of Life, and Treatment Landscape from the Patient\u2019s Perspective","volume":"39","author":"Ortiz","year":"2025","journal-title":"CNS Drugs"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.sleep.2024.06.028","article-title":"Barriers to therapy adherence in narcolepsy","volume":"121","author":"Finger","year":"2024","journal-title":"Sleep Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.jpsychores.2018.12.008","article-title":"Prospective memory in narcolepsy type 1 patients","volume":"117","author":"Tonetti","year":"2019","journal-title":"J. Psychosom. Res."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Tonetti, L., Occhionero, M., Boreggiani, M., Conca, A., Dondi, P., Elbaz, M., Fabbri, M., Gauriau, C., Giupponi, G., and Leger, D. (2020). Sleep and Prospective Memory: A Retrospective Study in Different Clinical Populations. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17176113"},{"key":"ref_8","unstructured":"Brandimonte, M., Einstein, G.O., and McDaniel, M.A. (1996). Varieties of intention: Some distinctions and classifications. Prospective Memory: Theory and Applications, Lawrence Erlbaum Associates Publishers."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1080\/13854046.2017.1394493","article-title":"Prospective memory impairment in idiopathic REM sleep behavior disorder","volume":"32","author":"Bezdicek","year":"2017","journal-title":"Clin. Neuropsychol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.sleep.2004.11.007","article-title":"The association between narcolepsy and REM behavior disorder (RBD)","volume":"3","author":"Nightingale","year":"2005","journal-title":"Sleep Med."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Occhionero, M., Tonetti, L., Conca, A., Giovagnoli, S., Giupponi, G., Zoppello, M., and Natale, V. (2023). Activity-Based Prospective Memory in ADHD during Motor Sleep Inertia. Sensors, 23.","DOI":"10.3390\/s23115181"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Tonetti, L., Occhionero, M., Giovagnoli, S., Giudetti, F., Briganti, E., and Natale, V. (2024). Activity-Based Prospective Memory and Motor Sleep Inertia in Insomnia. Brain Sci., 14.","DOI":"10.3390\/brainsci14121248"},{"key":"ref_13","first-page":"331","article-title":"Progress in automatic sleep\/wake scoring by wrist actigraph","volume":"17","author":"Cole","year":"1988","journal-title":"Sleep Res."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/09291016.2013.830510","article-title":"Sleep and prospective memory","volume":"45","author":"Fabbri","year":"2014","journal-title":"Biol. Rhythm Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1080\/09602011.2015.1074590","article-title":"Naturalistic prospective memory in older adults: Predictors of performance on a habitual task","volume":"27","author":"Cavuoto","year":"2017","journal-title":"Neuropsychol. Rehabil."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1740-3391-9-11","article-title":"Measuring the impact of apnea and obesity on circadian activity patterns using functional linear modelling of actigraphy data","volume":"9","author":"Wang","year":"2011","journal-title":"J. Circadian Rhythm."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Rose, N.S., Rendell, P.G., Hering, A., Kliegel, M., Bidelman, G.M., and Craik, F.I. (2015). Cognitive and neural plasticity in older adults\u2019 prospective memory following training with the Virtual Week computer game. Front. Hum. Neurosci., 9.","DOI":"10.3389\/fnhum.2015.00592"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/cdep.12121","article-title":"Transitions in executive function: Insights from developmental parallels between prospective memory and cognitive flexibility","volume":"9","author":"Mahy","year":"2015","journal-title":"Child Dev. Perspect."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.cogdev.2016.02.003","article-title":"Development and longitudinal relationships between children\u2019s executive functions, prospective memory, and metacognition","volume":"38","author":"Spiess","year":"2016","journal-title":"Cogn. Dev."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1080\/095414400340000240","article-title":"The role of executive processes in prospective memory tasks","volume":"16","author":"Aarts","year":"2004","journal-title":"Eur. J. Cogn. Psychol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1037\/a0030579","article-title":"The role of shifting, updating, and inhibition in prospective memory performance in young and older adults","volume":"49","author":"Schnitzspahn","year":"2013","journal-title":"Dev. Psychol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1111\/jgs.14134","article-title":"Improving Prospective Memory in Healthy Older Adults and Individuals with Very Mild Alzheimer\u2019s Disease","volume":"64","author":"Shelton","year":"2016","journal-title":"J. Am. Geriatr. Soc."},{"key":"ref_23","unstructured":"Gruneberg, M.M., Morris, P.E., and Sykes, R.N. (1988). Some observations on prospective remembering. Practical Aspects of Memory: Current Research and Issues, Vol. 1. Memory in Everyday Life, John Wiley & Sons."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/26\/9\/2681\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:24:19Z","timestamp":1777364659000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/26\/9\/2681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,26]]},"references-count":23,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["s26092681"],"URL":"https:\/\/doi.org\/10.3390\/s26092681","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,26]]}}}