{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:14:55Z","timestamp":1780481695262,"version":"3.54.1"},"reference-count":107,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Growing public concern over the living environment, food safety and the healthcare industry has spurred rapid advances in advanced sensing technology for environmental monitoring, food-safety screening, and biomedical surveillance. Consequently, developing a novel sensing strategy which is efficient, inexpensive, and easy to operate has become a major research focus in recent years. MnO2 nanostructures combine advantages of high specific surface area, quantum confinement, surface effects originating from their nanostructure, pronounced redox activity, broad optical absorption, distinctive electrochemical behavior, multiple accessible oxidation states, low cost and environmental benignity contributed by MnO2, which make them a critical material candidate for developing advanced sensing technology. This paper provides a comprehensive overview of MnO2 nanostructure-based novel sensors over the past five years. The contents of this review are listed as follows: (1) synthetic strategy and sensing advantages of MnO2 quantum dots, 1D MnO2, 2D MnO2 and hierarchical MnO2; (2) recent research advances in detection methodology and corresponding principles based on MnO2 nanostructures; and (3) the applicational progress of MnO2 nanostructure-based novel sensing technology in the field of food safety and biosensing. Finally, the foregoing discussion is integrated, and the current shortcomings and future development trends of novel sensors based on MnO2 nanostructures are critically assessed.<\/jats:p>","DOI":"10.3390\/s26113544","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T09:33:14Z","timestamp":1780479194000},"page":"3544","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["MnO2 Nanostructure-Based Novel Sensing: A Review"],"prefix":"10.3390","volume":"26","author":[{"given":"Haoyu","family":"Qi","sequence":"first","affiliation":[{"name":"School of Electronic Information, Northwest University, Xi\u2019an 710127, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Ji","sequence":"additional","affiliation":[{"name":"Xi\u2019an Aerospace Composites Research Institute, Xi\u2019an 710025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanjie","family":"Ji","sequence":"additional","affiliation":[{"name":"School of Energy and Power Engineering, Huazhong University of Science and Technology, Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Electronic Information, Northwest University, Xi\u2019an 710127, China"},{"name":"School of Chemical Engineering, Northwest University, Xi\u2019an 710127, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2202442","DOI":"10.1002\/advs.202202442","article-title":"Highly sensitive and selective gas sensors based on NiO\/MnO2@NiO nanosheets to detect allyl mercaptan gas released by humans under psychological stress","volume":"9","author":"Li","year":"2022","journal-title":"Adv. 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