{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:11:35Z","timestamp":1785409895293,"version":"3.56.0"},"reference-count":23,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Asahi Kasei Zoll Medical"},{"id":[{"id":"https:\/\/ror.org\/036wkjd70","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Background: Wearable cardioverter-defibrillators (WCDs) are equipped with the TRENDS remote-monitoring system, enabling continuous assessment of arrhythmias, physiological parameters, and patient-reported outcomes. This study evaluated the clinical utility of TRENDS-integrated WCD management and compared it with a historical control. Methods: We prospectively analyzed 36 consecutive patients who received a WCD with TRENDS between 2019 and 2024 and compared them with 30 historical controls treated before the implementation of TRENDS. Results: The WCD indications were heart failure as primary prevention (64%) and acute coronary syndrome with ventricular arrhythmias (28%). Among 18 patients who met the criteria for an implantable cardioverter-defibrillator (ICD), including 1 patient with WCD shock, 9 ultimately underwent ICD implantation. The mean daily WCD wear-time was 21.3 h and did not differ significantly from that of the historical control. The response rate to health-related questionnaires was 89%. TRENDS detected symptom exacerbation in 31% of patients, weight gain in 19% of patients, and missed medication in 19% of patients. Daily step-count was significantly lower in patients with ICD indications than in those without (5012 \u00b1 2980 steps vs. 7977 \u00b1 3584 steps, p = 0.01). TRENDS data also aided in initiating anticoagulation therapy and optimizing beta-blocker therapy. Conclusions: TRENDS provided clinically actionable physiologic and patient-reported information that supported individualized cardiovascular management.<\/jats:p>","DOI":"10.3390\/s26123952","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T01:03:23Z","timestamp":1782263003000},"page":"3952","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Utility of the TRENDS Remote Monitoring Function Integrated into a Wearable Cardioverter-Defibrillator"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9857-9281","authenticated-orcid":false,"given":"Yoshifumi","family":"Ikeda","sequence":"first","affiliation":[{"name":"Department of Cardiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Risa","family":"Kanai","sequence":"additional","affiliation":[{"name":"Department of Nursing, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7154-5807","authenticated-orcid":false,"given":"Yoshitaka","family":"Terazaki","sequence":"additional","affiliation":[{"name":"Department of Nursing, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhisa","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Narita","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wataru","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsukasa","family":"Naganuma","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomichi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritsushi","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1016\/j.jacc.2013.05.086","article-title":"Wearable cardioverter-defibrillator use in patients perceived to be at high risk early post-myocardial infarction","volume":"62","author":"Epstein","year":"2013","journal-title":"J. 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