{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T05:02:18Z","timestamp":1784437338666,"version":"3.55.0"},"reference-count":30,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Rapid room-temperature identification of gases and volatile organic compounds remains challenging for compact sensing platforms, particularly when chemically related analytes must be discriminated using accessible sensing materials. In this work, we evaluate whether magneto-optical surface plasmon resonance (MOSPR), combined with multi-spot sensing and conventional SPR readout from the same chip, can provide complementary response features for improved gas\/VOC discrimination. The sensing spots are made from accessible chemicals and nanoparticles with plasmonic and magnetic properties. The sensor chip consists of a multilayer structure of metallic materials with both plasmonic and magnetic properties featuring enhanced sensitivity and stability. Measurements are made using a custom-built MOSPR instrument at relevant analyte concentrations. Analyte-specific sensor channels were selected for concentration-dependent calibration while the complete multivariate data were first explored using principal component analysis for supervised analyte classification. The combined 16-feature MOSPR\/SPR model achieved an overall accuracy of 88.3% and a balanced accuracy of 87.6% under leave-one-concentration-block-out cross-validation compared with 66.2% and 65.7%, respectively, for the SPR measurement alone. These results show that MOSPR provides response information that encompasses and extends that obtained from conventional SPR measurements, thereby improving analyte discrimination. The proposed approach may provide a basis for future environmental monitoring and industrial process control, including real-time monitoring of harmful gaseous emissions pending further validation under application-specific conditions.<\/jats:p>","DOI":"10.3390\/s26144537","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T09:00:52Z","timestamp":1784278852000},"page":"4537","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Magneto-Optical Surface Plasmon Resonance Multi-Spot Assay for Identification and Quantification of Gaseous Compounds at Room Temperature"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9737-090X","authenticated-orcid":false,"given":"Sorin","family":"David","sequence":"first","affiliation":[{"name":"International Centre of Biodynamics, Intrarea Portocalelor 1B, Sector 6, 060101 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5647-7743","authenticated-orcid":false,"given":"Cristina","family":"Polonschii","sequence":"additional","affiliation":[{"name":"International Centre of Biodynamics, Intrarea Portocalelor 1B, Sector 6, 060101 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena Gabriela","family":"Cocos-Barbu","sequence":"additional","affiliation":[{"name":"Faculty of Medical Engineering, University Politehnica of Bucharest, Splaiul Independen\u0163ei nr. 313, Sector 6, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dumitru","family":"Bratu","sequence":"additional","affiliation":[{"name":"International Centre of Biodynamics, Intrarea Portocalelor 1B, Sector 6, 060101 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugen","family":"Gheorghiu","sequence":"additional","affiliation":[{"name":"International Centre of Biodynamics, Intrarea Portocalelor 1B, Sector 6, 060101 Bucharest, Romania"},{"name":"Faculty of Biology, University of Bucharest, Blvd. Regina Elisabeta, 030018 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,17]]},"reference":[{"key":"ref_1","unstructured":"Yu, M.-H., Tsunoda, H., and Tsunoda, M. 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