{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T13:35:49Z","timestamp":1786541749026,"version":"build-2736575974"},"reference-count":33,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Aminogram society"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Background: Although dual-energy X-ray absorptiometry (DXA) is the reference method for measuring appendicular skeletal muscle mass (ASMM) and diagnosing sarcopenia, seated bioelectrical impedance analysis (BIA) may represent a practical alternative. As its validity remains still insufficiently documented in specific populations, the objective is to evaluate the agreement between seated BIA and DXA, and examine associations between phase angle (PhA) and physical performance in old adults. Methods: Fifty-nine old adults (75 \u00b1 7 years) underwent DXA and seated BIA (Biody XpertZM3). ASMM was estimated using the Kyle and Sergi equations. Agreement with DXA was assessed using Lin\u2019s concordance correlation coefficient (CCC), Bland\u2013Altman analysis, root mean square error (RMSE) and mean absolute error (MAE). Associations between PhA, handgrip strength, and five-times sit-to-stand (5-STS) performance were evaluated. Results: Both equations showed good agreement with DXA, but the Sergi equation performed better, with higher concordance (CCC = 0.942 vs. 0.898), lower bias (0.44 vs. 1.11 kg), and lower RMSE (1.33 vs. 1.96 kg). PhA correlated positively with handgrip strength (r = 0.315, p = 0.015) but was not associated with 5-STS. Conclusions: Seated BIA provides clinically acceptable estimates of ASMM in older adults. The Sergi equation demonstrated superior accuracy, supporting population-specific equations. PhA may provide additional information on muscle quality and sarcopenia.<\/jats:p>","DOI":"10.3390\/s26165112","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T12:53:48Z","timestamp":1786539228000},"page":"5112","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Toward Clinically Feasible Assessment of Muscle Mass: Validation of a Seated Bioelectrical Impedance Device Against Dual-Energy X-Ray Absorptiometry (DXA) in Older Adults"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4825-6593","authenticated-orcid":false,"given":"Elodie","family":"Piche","sequence":"first","affiliation":[{"name":"Laboratoire Motricit\u00e9 Humaine \u00c9ducation Sport Sant\u00e9 (LAMHESS), Universit\u00e9 C\u00f4te d\u2019Azur, 06100 Nice, France"},{"name":"Clinique G\u00e9riatrique du Cerveau et du Mouvement, Centre Hospitalier Universitaire de Nice, 06100 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5082-1817","authenticated-orcid":false,"given":"Emeline","family":"Michel","sequence":"additional","affiliation":[{"name":"Laboratoire Motricit\u00e9 Humaine \u00c9ducation Sport Sant\u00e9 (LAMHESS), Universit\u00e9 C\u00f4te d\u2019Azur, 06100 Nice, France"},{"name":"Clinique G\u00e9riatrique du Cerveau et du Mouvement, Centre Hospitalier Universitaire de Nice, 06100 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Guerin","sequence":"additional","affiliation":[{"name":"Clinique G\u00e9riatrique du Cerveau et du Mouvement, Centre Hospitalier Universitaire de Nice, 06100 Nice, France"},{"name":"Institute for Research on Cancer and Aging Nice (IRCAN), CNRS UMR 7284\/INSERM U108, Facult\u00e9 de M\u00e9decine, Universit\u00e9 C\u00f4te d\u2019Azur, 06100 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1377-5318","authenticated-orcid":false,"given":"Etienne","family":"Gouraud","sequence":"additional","affiliation":[{"name":"Aminogram SAS, 13600 La Ciotat, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Chorin","sequence":"additional","affiliation":[{"name":"Laboratoire Motricit\u00e9 Humaine \u00c9ducation Sport Sant\u00e9 (LAMHESS), Universit\u00e9 C\u00f4te d\u2019Azur, 06100 Nice, France"},{"name":"Clinique G\u00e9riatrique du Cerveau et du Mouvement, Centre Hospitalier Universitaire de Nice, 06100 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/ageing\/afz046","article-title":"Erratum: Sarcopenia: Revised European consensus on definition and diagnosis","volume":"48","author":"Bahat","year":"2019","journal-title":"Age Ageing"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s40520-016-0709-0","article-title":"Nutrition, frailty, and sarcopenia","volume":"29","author":"Kiesswetter","year":"2017","journal-title":"Aging Clin. 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