{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:52:31Z","timestamp":1787313151071,"version":"build-2736575974"},"reference-count":37,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T00:00:00Z","timestamp":1736812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tomography"],"abstract":"<jats:p>Background\/Objectives: The aim was to investigate the association between variations in the dorsal pancreatic artery (DPA) and intrapancreatic arcade anatomy with Whipple procedure outcomes and postoperative complications. Methods: This retrospective study was conducted with 362 patients who underwent a Whipple procedure at the Department of Gastroenterological Surgery of Adana City Training and Research Hospital between January 2018 and April 2024. All data collected from medical records were compared and statistically analyzed according to the patients\u2019 survival status and arcade subtypes. Results: After excluding cases that did not meet the study criteria, a total of 284 patients were included in the study. DPA was visualized in 55.98% (159\/284) of patients, while the intrapancreatic arcade was observed in 25% (71\/284). The most common origin of the DPA was the splenic artery in 69.2% (n = 110) of patients, followed by the superior mesenteric artery in 17.6% (n = 28). The frequency of intrapancreatic arcade anatomy variations was as follows: type 1: 28.2% (n = 20), type 2: 49.3% (n = 35) and type 3: 22.5% (n = 16). Arcade type 4 anatomy was not detected. Postoperative pancreatic fistula (POPF) complication was found to be statistically significantly higher in patients with type 3 anatomy (p = 0.042). The 90-day mortality and long-term mortality rates did not differ among the groups based on the variations in both DPA and intrapancreatic arcade anatomy types. Conclusions: Patients with intrapancreatic arcade type 3 anatomy had a higher risk of POPF complications. Determination of preoperative arcade type by computed tomography (CT) angiography may help to predict the risk of POPF.<\/jats:p>","DOI":"10.3390\/tomography11010009","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T11:28:31Z","timestamp":1736854111000},"page":"9","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["CT Angiography Assessment of Dorsal Pancreatic Artery and Intrapancreatic Arcade Anatomy: Impact on Whipple Surgery Outcomes"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2335-1538","authenticated-orcid":false,"given":"Gorkem","family":"Ozdemir","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery, Adana City Training and Research Hospital, 01370 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tolga","family":"Olmez","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Adana City Training and Research Hospital, 01370 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Okan","family":"Dilek","sequence":"additional","affiliation":[{"name":"Department of Radiology, Adana City Training and Research Hospital, 01370 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3745-7827","authenticated-orcid":false,"given":"Berkay","family":"Eyi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Adana City Training and Research Hospital, 01370 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1039-9011","authenticated-orcid":false,"given":"Alper","family":"Sozutek","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Adana City Training and Research Hospital, 01370 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Seker","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Adana City Training and Research Hospital, 01370 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,14]]},"reference":[{"key":"ref_1","first-page":"62","article-title":"Comparison of intraoperative versus delayed enteral feeding tube placement in patients undergoing a Whipple procedure","volume":"16","author":"Scaife","year":"2014","journal-title":"HBP"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jss.2013.01.016","article-title":"Classic Whipple versus pylorus-preserving pancreaticoduodenectomy in the ACS NSQIP","volume":"183","author":"Leichtle","year":"2013","journal-title":"J. Surg. Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.soc.2005.05.006","article-title":"Pancreaticoduodenectomy (Whipple operation)","volume":"14","author":"Clancy","year":"2005","journal-title":"Surg. Oncol. Clin. N. Am."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.amjsurg.2014.04.015","article-title":"The effect of antecolic versus retrocolic reconstruction on delayed gastric emptying after classic non-pylorus preserving pancreaticoduodenectomy","volume":"209","author":"Sahora","year":"2015","journal-title":"Am. J. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0002-9610(00)00418-9","article-title":"Enteral nutrition prolongs delayed gastric emptying in patients after Whipple resection","volume":"180","author":"Martignoni","year":"2000","journal-title":"Am. J. Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.ijsu.2012.06.003","article-title":"Robot-assisted laparoscopic pancreaticoduodenectomy versus open pancreaticoduodenectomy\u2014A comparative study","volume":"10","author":"Lai","year":"2012","journal-title":"Int. J. Surg."},{"key":"ref_7","first-page":"319","article-title":"Morphological analysis of the branches of the dorsal pancreatic artery and their clinical significance","volume":"81","author":"Tsutsumi","year":"2020","journal-title":"J. Neurol. Surg. Part B Skull Base"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e35049","DOI":"10.1097\/MD.0000000000035049","article-title":"Vascular supply of postresection pancreatic remnant after pancreaticoduodenectomy: A cadaveric study","volume":"102","author":"Rousek","year":"2023","journal-title":"Medicine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1007\/s00276-023-03235-3","article-title":"MDCT evaluation of Dorsal Pancreatic Artery and Intrapancreatic arcadee anatomy","volume":"45","author":"Sharma","year":"2023","journal-title":"Surg. Radiol. Anat."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"3935","DOI":"10.1007\/s00261-021-02983-3","article-title":"CT reporting of relevant vascular variations and its implication in pancreatoduodenectomy","volume":"46","author":"Appanraj","year":"2021","journal-title":"Abdom. Radiol."},{"key":"ref_11","first-page":"930","article-title":"Surgical and oncological implications of aberrant arterial anatomy in patients undergoing pancreatoduodenectomy","volume":"70","author":"Khan","year":"2020","journal-title":"J. Pak. Med. Assoc."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1007\/s00268-021-06231-z","article-title":"The Impact of Aberrant Hepatic Artery on Resection Margin and Outcomes of Laparoscopic Pancreatoduodenectomy: A Single-Center Report","volume":"45","author":"Wang","year":"2021","journal-title":"World J. Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.21873\/invivo.11601","article-title":"Does Aberrant Right Hepatic Artery Infuence the Surgical Short- and Long-term Outcome of Pancreatoduodenectomy?","volume":"33","author":"Crocetti","year":"2019","journal-title":"In Vivo"},{"key":"ref_14","first-page":"25","article-title":"Incidence and management of arterial anomalies in patients undergoing pancreaticoduodenectomy","volume":"11","author":"Perwaiz","year":"2010","journal-title":"J. Pancreas"},{"key":"ref_15","first-page":"649","article-title":"Transpancreatic hepatomesenteric trunk complicating pancreaticoduodenectomy","volume":"14","author":"Rammohan","year":"2013","journal-title":"J. Pancreas"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s12029-021-00598-x","article-title":"Hepatic Arterial Variations and Its Implication During Pancreatic Cancer Surgeries","volume":"52","author":"Swami","year":"2021","journal-title":"J. Gastrointest Cancer"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"3728","DOI":"10.1007\/s00464-024-10887-8","article-title":"Impact of hepatic artery variation on surgical and oncological outcomes in robotic pancreaticoduodenectomy","volume":"38","author":"Yu","year":"2024","journal-title":"Surg. Endosc."},{"key":"ref_18","first-page":"5804047","article-title":"The Arterial Supply of the Distal Part of the Pancreas","volume":"2019","author":"Covantev","year":"2019","journal-title":"Surg. Res. Pract."},{"key":"ref_19","first-page":"518","article-title":"Proposed classification of complications of surgery with examples of utility in cholecystectomy","volume":"111","author":"Clavien","year":"1992","journal-title":"Surgery"},{"key":"ref_20","first-page":"250","article-title":"Timing of elective surgery as a perioperative outcome variable: Analysis of pancreaticoduodenectomy","volume":"16","author":"Araujo","year":"2014","journal-title":"HBP"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1245\/s10434-009-0757-1","article-title":"Vascular Anomalies Encountered During Pancreatoduodenectomy: Do They Influence Outcomes?","volume":"17","author":"Shukla","year":"2010","journal-title":"Ann. Surg. Oncol."},{"key":"ref_22","first-page":"758","article-title":"Justification for visceral angiography prior to pancreaticoduodenectomy","volume":"64","author":"Volpe","year":"1998","journal-title":"Am. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Chawla, S., Kumar, B., Arora, N., and Kumar, A. (2024). Major anatomical variations in branches of common hepatic artery and dorsal pancreatic artery with its surgical significance: A case report. Int. J. Sci. Res., 13.","DOI":"10.36106\/ijsr\/2504546"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1002\/ca.23063","article-title":"Pancreaticoduodenal arterial arcades: Their dominance and variations-their potential clinical relevance","volume":"31","author":"Korom","year":"2018","journal-title":"Clin. Anat."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/ca.22885","article-title":"Anatomo-radiological patterns of pancreatic vascularization, with surgical implications: Clinical and anatomical study","volume":"30","author":"Macchi","year":"2017","journal-title":"Clin. Anat."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/BF01653138","article-title":"The arterial blood supply of the pancreas: A review. V. The dorsal pancreatic artery. An anatomic review and a radiologic study","volume":"20","author":"Bertelli","year":"1998","journal-title":"Surg. Radiol. Anat."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/jhbp.901","article-title":"Precision anatomy for safe approach to pancreatoduodenectomy for both open and minimally invasive procedure: A systematic review","volume":"29","author":"Nakata","year":"2022","journal-title":"J. Hepatobiliary Pancreat. Sci."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.surg.2016.11.014","article-title":"The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After","volume":"161","author":"Bassi","year":"2017","journal-title":"Surgery"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jamcollsurg.2012.09.002","article-title":"A prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy","volume":"216","author":"Callery","year":"2013","journal-title":"J. Am. Coll. Surg."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"zrad106","DOI":"10.1093\/bjsopen\/zrad106","article-title":"Postoperative complications after pancreatoduodenectomy for malignancy: Results from the Recurrence After Whipple\u2019s (RAW) study","volume":"7","author":"Russell","year":"2023","journal-title":"BJS Open"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Kolbinger, F.R., Lambrecht, J., Leger, S., Ittermann, T., Speidel, S., Weitz, J., Hoffmann, R.T., Distler, M., and K\u00fchn, J.P. (2022). The image-based preoperative fistula risk score (preFRS) predicts postoperative pancreatic fistula in patients undergoing pancreatic head resection. Sci. Rep., 12.","DOI":"10.1038\/s41598-022-07970-2"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/SLA.0000000000002714","article-title":"The Beneficial Effects of Minimizing Blood Loss in Pancreatoduodenectomy","volume":"270","author":"Seykora","year":"2019","journal-title":"Ann. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.surg.2021.03.044","article-title":"The effect of high intraoperative blood loss on pancreatic fistula development after pancreatoduodenectomy: An international, multi-institutional propensity score matched analysis","volume":"170","author":"Casciani","year":"2021","journal-title":"Surgery"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s00464-020-07417-7","article-title":"The anatomical features of dorsal pancreatic artery in the pancreatic head and its clinical significance in laparoscopic pancreatoduodenectomy","volume":"35","author":"Jiang","year":"2021","journal-title":"Surg. Endosc."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/MPA.0000000000000035","article-title":"Three-dimensional reconstruction of the peripancreatic vascular system based on computed tomographic angiography images and its clinical application in the surgical management of pancreatic tumors","volume":"43","author":"Fang","year":"2014","journal-title":"Pancreas"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1148\/radiology.208.2.9680589","article-title":"Pancreatic arterial anatomy: Depiction with dual-phase helical CT","volume":"208","author":"Chong","year":"1998","journal-title":"Radiology"},{"key":"ref_37","first-page":"517","article-title":"The significance of the morphology of the dorsal pancreatic artery in determining the presence of the accessory right hepatic artery passing behind the portal vein","volume":"73","author":"Matsumura","year":"1998","journal-title":"Kaibogaku Zasshi J. Anat."}],"container-title":["Tomography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2379-139X\/11\/1\/9\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:28:43Z","timestamp":1759919323000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2379-139X\/11\/1\/9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,14]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1]]}},"alternative-id":["tomography11010009"],"URL":"https:\/\/doi.org\/10.3390\/tomography11010009","relation":{},"ISSN":["2379-139X"],"issn-type":[{"value":"2379-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,14]]}}}