{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:09:36Z","timestamp":1791493776271,"version":"4.3.4"},"reference-count":14,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T00:00:00Z","timestamp":1633478400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tomography"],"abstract":"<jats:p>Background: non-hemorrhagic adrenal infarction (NHAI) is a rare cause of acute abdominal\/flank pain during pregnancy; in order to ensure prompt and appropriate treatment, this diagnosis should not be overlooked. This case series highlights pertinent imaging findings, including ultrasounds (USs), computed tomography (CT), and magnetic resonance imaging (MRI) of recent NHAI cases. Methods: we compiled all consecutive NHAI cases from two university hospitals over a two-year period and checked the relevant clinical, laboratory, and imaging findings. Relevant articles on NHAI published from January 2010 to March 2021 were analyzed. Results: six cases were found in our database. CT-scans typically showed enlarged, hypodense, and non-enhanced adrenal glands. Unenhanced MRIs allowed for diagnoses and showed enlarged adrenal glands in the signal hyperintensity on T2 and diffusion-weighted imaging, without any signal hyperintensity on T1. In two of our six cases, USs showed swollen adrenal glands with fluid collection. Conclusion: NHAI and its differential diagnosis\u2014in cases of acute pain during pregnancy\u2014highlight the crucial roles of integrated radiological examination and cooperation between obstetricians and radiologists, both of whom should consider the location of the pain, the accessibility and tolerance of MRI, and the radiation exposure of CT. Despite its supposed poor sensitivity, an US performed because the patient reports pain should also be used to examine the adrenal gland regions. Non-enhanced MRI is clearly of value and access to it in emergencies is important to avoid radiation exposure<\/jats:p>","DOI":"10.3390\/tomography7040046","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T21:47:34Z","timestamp":1633988854000},"page":"533-544","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Non-Hemorrhagic Adrenal Infarction during Pregnancy: The Diagnostic Imaging Keys"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3992-537X","authenticated-orcid":false,"given":"Pierre","family":"Chagu\u00e9","sequence":"first","affiliation":[{"name":"AP-HP, H\u00f4pital Antoine B\u00e9cl\u00e8re, Service de Radiologie, 92140 Clamart, France"},{"name":"Facult\u00e9 de M\u00e9decine Paris-Sud, Universit\u00e9 Paris-Saclay, 94270 Le Kremlin Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Marchi","sequence":"additional","affiliation":[{"name":"AP-HP, H\u00f4pital Antoine B\u00e9cl\u00e8re, Service de Radiologie, 92140 Clamart, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alix","family":"Fechner","sequence":"additional","affiliation":[{"name":"AP-HP, H\u00f4pital Antoine B\u00e9cl\u00e8re, Service de Radiologie, 92140 Clamart, France"},{"name":"Facult\u00e9 de M\u00e9decine Paris-Sud, Universit\u00e9 Paris-Saclay, 94270 Le Kremlin Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghina","family":"Hindawi","sequence":"additional","affiliation":[{"name":"AP-HP, H\u00f4pital Kremlin Bic\u00eatre, Service de Radiologie, 94270 Le Kremlin Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadrien","family":"Tranchart","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine Paris-Sud, Universit\u00e9 Paris-Saclay, 94270 Le Kremlin Bic\u00eatre, France"},{"name":"AP-HP, H\u00f4pital Antoine B\u00e9cl\u00e8re, Service de Chirurgie Digestive, 92140 Clamart, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7064-6008","authenticated-orcid":false,"given":"Julie","family":"Carrara","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine Paris-Sud, Universit\u00e9 Paris-Saclay, 94270 Le Kremlin Bic\u00eatre, France"},{"name":"AP-HP, H\u00f4pital Antoine B\u00e9cl\u00e8re, Service de Gyn\u00e9cologie-Obst\u00e9trique, 92140 Clamart, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4921-0047","authenticated-orcid":false,"given":"Alexandre J.","family":"Vivanti","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine Paris-Sud, Universit\u00e9 Paris-Saclay, 94270 Le Kremlin Bic\u00eatre, France"},{"name":"AP-HP, H\u00f4pital Antoine B\u00e9cl\u00e8re, Service de Gyn\u00e9cologie-Obst\u00e9trique, 92140 Clamart, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Rocher","sequence":"additional","affiliation":[{"name":"AP-HP, H\u00f4pital Antoine B\u00e9cl\u00e8re, Service de Radiologie, 92140 Clamart, France"},{"name":"Facult\u00e9 de M\u00e9decine Paris-Sud, Universit\u00e9 Paris-Saclay, 94270 Le Kremlin Bic\u00eatre, France"},{"name":"BIOMAPS, UMR 9011 Universit\u00e9 Paris-Saclay, 4 pl. du G\u00e9n\u00e9ral Leclerc, CEDEX, 91401 Orsay, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.mric.2015.11.007","article-title":"Magnetic Resonance Imaging of Abdominal and Pelvic Pain in the Pregnant Patient","volume":"24","author":"Baheti","year":"2016","journal-title":"Magn. Reson. Imaging Clin. North Am."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.2214\/AJR.17.18739","article-title":"Acute Nonhemorrhagic Adrenal Infarction in Pregnancy: 10-Year MRI Incidence and Patient Outcomes at a Single Institution","volume":"210","author":"Glomski","year":"2018","journal-title":"Am. J. Roentgenol."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Chasseloup, F., Bourcigaux, N., and Christin-Maitre, S. (2019). Unilateral non-haemorrhagic adrenal infarction as a cause of abdominal pain during pregnancy. Gynecol. Endocrinol. Off. J. Int. Soc. Gynecol. Endocrinol.","DOI":"10.1530\/endoabs.63.P17"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/s10140-017-1530-6","article-title":"Usefulness of diffusion-weighted imaging for diagnosis of adrenal ischemia during pregnancy: A preliminary report","volume":"24","author":"Gaudineau","year":"2017","journal-title":"Emerg. Radiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1080\/01443615.2018.1472557","article-title":"Adrenal infarction in the immediate postnatal period\u2020","volume":"39","author":"Cunningham","year":"2018","journal-title":"J. Obstet. Gynaecol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"220","DOI":"10.2214\/ajr.183.1.1830220","article-title":"Sequential Adrenal Infarction without MRI-Detectable Hemorrhage in Primary Antiphospholipid-Antibody Syndrome","volume":"183","author":"Riddell","year":"2004","journal-title":"Am. J. Roentgenol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/AOG.0000000000000884","article-title":"Nonhemorrhagic Adrenal Infarction with Magnetic Resonance Imaging Features during Pregnancy","volume":"126","author":"Guenette","year":"2015","journal-title":"Obstet. Gynecol."},{"key":"ref_8","first-page":"95","article-title":"Thrombotic risk during pregnancy: A population study","volume":"94","author":"Lindqvist","year":"1999","journal-title":"Obstet. Gynecol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jgyn.2009.09.012","article-title":"Adrenal vein thrombosis during pregnancy","volume":"39","author":"Schmitt","year":"2010","journal-title":"J. Gynecol. Obstet Biol. Reprod."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Green, P.-A.D., Ngai, I.M., Lee, T.T., and Garry, D.J. (2013). Unilateral adrenal infarction in pregnancy. BMJ Case Rep., 2013.","DOI":"10.1136\/bcr-2013-009997"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/path.1711190202","article-title":"Venous infarction of the adrenal glands","volume":"119","author":"Fox","year":"1976","journal-title":"J. Pathol."},{"key":"ref_12","first-page":"93","article-title":"Renal colic during pregnancy: Diagnostic and therapeutic aspects. Literature review","volume":"70","author":"Blanco","year":"2016","journal-title":"Central Eur. J. Urol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"129","DOI":"10.2174\/1573405613666171020110522","article-title":"Value of Magnetic Resonance Urography Versus Computerized Tomography Urography (CTU) in Evaluation of Obstructive Uropathy: An Observational Study","volume":"14","author":"Bafaraj","year":"2017","journal-title":"Med Imaging Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1007\/s00330-017-5246-5","article-title":"Post-contrast acute kidney injury-Part 1: Definition, clinical features, incidence, role of contrast medium and risk factors: Recommendations for updated ESUR Contrast Medium Safety Committee guidelines","volume":"28","author":"Reimer","year":"2018","journal-title":"Eur. 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