{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:03:45Z","timestamp":1777521825353,"version":"3.51.4"},"reference-count":35,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tomography"],"abstract":"<jats:p>The High-Resolution Computed Tomography (HRCT) detection and diagnosis of diffuse lung disease is primarily based on the recognition of a limited number of specific abnormal findings, pattern combinations or their distributions, as well as anamnesis and clinical information. Since texture recognition has a very high accuracy percentage if a complex network approach is used, this paper aims to implement such a technique customized for diffuse interstitial lung diseases (DILD). The proposed procedure translates HRCT lung imaging into complex networks by taking samples containing a secondary lobule, converting them into complex networks and analyzing them in three dimensions: emphysema, ground glass opacity, and consolidation. This method was evaluated on a 60-patient lot and the results showed a clear, quantifiable difference between healthy and affected lungs. By deconstructing the image on three pathological axes, the method offers an objective way to quantify DILD details which, so far, have only been analyzed subjectively.<\/jats:p>","DOI":"10.3390\/tomography8040162","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T01:41:16Z","timestamp":1659058876000},"page":"1928-1946","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A Novel Method for Lung Image Processing Using Complex Networks"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1635-5626","authenticated-orcid":false,"given":"Laura","family":"Broasc\u0103","sequence":"first","affiliation":[{"name":"Department of Computer and Information Technology, Automation and Computers Faculty, \u201cPolitehnica\u201d University of Timi\u0219oara, Vasile P\u00e2rvan Blvd. No. 2, 300223 Timi\u0219oara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5270-1464","authenticated-orcid":false,"given":"Ana Adriana","family":"Tru\u0219culescu","sequence":"additional","affiliation":[{"name":"Pulmonology Department, \u2018Victor Babes\u2019 University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timi\u0219oara, Romania"},{"name":"Center for Research and Innovation in Precision Medicine of Respiratory Diseases (CRIPMRD), \u2018Victor Babes\u2019, University of Medicine and Pharmacy, 300041 Timi\u0219oara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4840-1925","authenticated-orcid":false,"given":"Versavia Maria","family":"Ancu\u0219a","sequence":"additional","affiliation":[{"name":"Department of Computer and Information Technology, Automation and Computers Faculty, \u201cPolitehnica\u201d University of Timi\u0219oara, Vasile P\u00e2rvan Blvd. No. 2, 300223 Timi\u0219oara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Horia","family":"Cioc\u00e2rlie","sequence":"additional","affiliation":[{"name":"Department of Computer and Information Technology, Automation and Computers Faculty, \u201cPolitehnica\u201d University of Timi\u0219oara, Vasile P\u00e2rvan Blvd. No. 2, 300223 Timi\u0219oara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2083-0581","authenticated-orcid":false,"given":"Cristian-Iulian","family":"Oancea","sequence":"additional","affiliation":[{"name":"Pulmonology Department, \u2018Victor Babes\u2019 University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timi\u0219oara, Romania"},{"name":"Center for Research and Innovation in Precision Medicine of Respiratory Diseases (CRIPMRD), \u2018Victor Babes\u2019, University of Medicine and Pharmacy, 300041 Timi\u0219oara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4620-3340","authenticated-orcid":false,"given":"Emil-Robert","family":"Stoicescu","sequence":"additional","affiliation":[{"name":"Department of Radiology and Medical Imaging, \u2018Victor Babes\u2019 University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timi\u0219oara, Romania"},{"name":"Research Center for Pharmaco-Toxicological Evaluations, \u2018Victor Babes\u2019 University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timi\u0219oara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Lumini\u021ba","family":"Manolescu","sequence":"additional","affiliation":[{"name":"Center for Research and Innovation in Precision Medicine of Respiratory Diseases (CRIPMRD), \u2018Victor Babes\u2019, University of Medicine and Pharmacy, 300041 Timi\u0219oara, Romania"},{"name":"Department of Radiology and Medical Imaging, \u2018Victor Babes\u2019 University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timi\u0219oara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"976","DOI":"10.4065\/82.8.976","article-title":"Diagnosis of Interstitial Lung Diseases","volume":"82","author":"Ryu","year":"2007","journal-title":"Mayo Clin. 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