{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:32:48Z","timestamp":1760232768204,"version":"build-2065373602"},"reference-count":22,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,11,20]],"date-time":"2022-11-20T00:00:00Z","timestamp":1668902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["321542"],"award-info":[{"award-number":["321542"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxics"],"abstract":"<jats:p>We aimed to report the results from the Global Burden of Disease Study 2019 related to respiratory malignant tumors (tracheal, bronchial, and lung) in Mexico. We also evaluated the relationship between the burden of these neoplasms and the proportion of daily smokers and total lead emissions in 2019. A cross-sectional analysis of ecological data was performed. The burden of these tumors was 152,189 disability-adjusted life-years (DALYs), and years of life lost (YLL) contributed to 99% of them. The highest DALYs rates (per 100,000) were observed in the states of Sinaloa, Chihuahua, Baja California Sur, Sonora, and Nayarit. We documented a linear relationship between the DALYs rates and the prevalence of daily smokers (\u03b2 = 8.50, 95% CI 1.58\u201315.38) and the total lead emissions (tons\/year: \u03b2 = 4.04, 95% CI 0.07\u20138.01). If later replicated, our study would provide insight into the major relevance of regulating tobacco use and the activities associated with the production of lead dust and other hazardous contaminants.<\/jats:p>","DOI":"10.3390\/toxics10110708","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T04:33:32Z","timestamp":1669005212000},"page":"708","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Insight into the Burden of Malignant Respiratory Tumors and their Relationship with Smoking Rates and Lead Contamination in Mexico"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9614-4946","authenticated-orcid":false,"given":"Oliver","family":"Mendoza-Cano","sequence":"first","affiliation":[{"name":"Facultad de Ingenier\u00eda Civil, Universidad de Colima, km. 9 Carretera Colima-Coquimatl\u00e1n, Coquimatl\u00e1n C.P. 28400, Colima, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1118-498X","authenticated-orcid":false,"given":"Efr\u00e9n","family":"Murillo-Zamora","sequence":"additional","affiliation":[{"name":"Departamento de Epidemiolog\u00eda, Unidad de Medicina Familiar No. 19, Instituto Mexicano del Seguro Social, Av. Javier Mina 301, Col. Centro, Colima C.P. 28000, Colima, Mexico"},{"name":"Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las V\u00edboras, Colima C.P. 28040, Colima, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngeles Catalina","family":"Ochoa-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Laboratorio de Toxicolog\u00eda Molecular, Centro de Investigaci\u00f3n Aplicada en Ambiente y Salud (CIAAS), Coordinaci\u00f3n Para La Innovaci\u00f3n y Aplicaci\u00f3n de La Ciencia y La Tecnolog\u00eda (CIACyT), Universidad Aut\u00f3noma de San Luis Potos\u00ed, Av. Sierra Leona 550, Col. Lomas Segunda Secci\u00f3n, San Luis Potos\u00ed C.P. 78210, San Luis Potos\u00ed, Mexico"},{"name":"Facultad de Medicina, Universidad Aut\u00f3noma de San Luis Potos\u00ed, Av. Venustiano Carranza 2405, Col. Lomas los Filtros, San Luis Potos\u00ed C.P. 78210, San Luis Potos\u00ed, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria Argentina","family":"Mendoza-Olivo","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Qu\u00edmicas, Universidad de Colima, km. 9 Carretera Colima-Coquimatl\u00e1n, Coquimatl\u00e1n C.P. 28400, Colima, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2883-4619","authenticated-orcid":false,"given":"M\u00f3nica","family":"R\u00edos-Silva","sequence":"additional","affiliation":[{"name":"Centro Universitario de Investigaciones Biom\u00e9dicas, Universidad de Colima\u2014CONACyT, Av. 25 de Julio 965, Col. Villas San Sebasti\u00e1n, Colima C.P. 28045, Colima, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8146-5667","authenticated-orcid":false,"given":"X\u00f3chitl","family":"Trujillo","sequence":"additional","affiliation":[{"name":"Centro Universitario de Investigaciones Biom\u00e9dicas, Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebasti\u00e1n, Colima C.P. 28045, Colima, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8515-0777","authenticated-orcid":false,"given":"Miguel","family":"Huerta","sequence":"additional","affiliation":[{"name":"Centro Universitario de Investigaciones Biom\u00e9dicas, Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebasti\u00e1n, Colima C.P. 28045, Colima, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5667-5179","authenticated-orcid":false,"given":"Jaime Alberto","family":"Bricio-Barrios","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las V\u00edboras, Colima C.P. 28040, Colima, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7678-5006","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"Benites-God\u00ednez","sequence":"additional","affiliation":[{"name":"Coordinaci\u00f3n de Educaci\u00f3n en Salud, Instituto Mexicano del Seguro Social, Calzada del Ejercito Nacional 14, Col. Fray Jun\u00edpero Serra, Tepic C.P. 63160, Nayarit, Mexico"},{"name":"Unidad Acad\u00e9mica de Medicina, Universidad Aut\u00f3noma de Nayarit, Ciudad de la Cultura Amado Nervo, Tepic C.P. 631555, Nayarit, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0044-9196","authenticated-orcid":false,"given":"Irma","family":"Gonz\u00e1lez-Curiel","sequence":"additional","affiliation":[{"name":"Unidad Acad\u00e9mica de Ciencias Qu\u00edmicas, Universidad Aut\u00f3noma de Zacatecas, Campus UAZ, Siglo XXI. Carr. Zacatecas-Guadalajara Km. 6., Zacatecas C.P. 98160, Zacatecas, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8293-1666","authenticated-orcid":false,"given":"Rebeca Yasm\u00edn","family":"P\u00e9rez-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Chemistry, DCNE, University of Guanajuato, Campus Guanajuato, Guanajuato C.P. 36700, Guanajuato, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia Azenet","family":"Pelallo-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Facultad de Ingenier\u00eda Civil, Universidad de Colima, km. 9 Carretera Colima-Coquimatl\u00e1n, Coquimatl\u00e1n C.P. 28400, Colima, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6689-2783","authenticated-orcid":false,"given":"Agust\u00edn","family":"Lugo-Radillo","sequence":"additional","affiliation":[{"name":"CONACYT\u2014Faculty of Medicine and Surgery, Universidad Aut\u00f3noma Benito Ju\u00e1rez de Oaxaca, Oaxaca C.P. 68020, Oaxaca, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1002\/ijc.31937","article-title":"Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods","volume":"144","author":"Ferlay","year":"2019","journal-title":"Int. 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Available online: https:\/\/uk.practicallaw.thomsonreuters.com\/7-508-8956?transitionType=Default&contextData=(sc.Default)&firstPage=true."}],"container-title":["Toxics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2305-6304\/10\/11\/708\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:22:27Z","timestamp":1760145747000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2305-6304\/10\/11\/708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,20]]},"references-count":22,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2022,11]]}},"alternative-id":["toxics10110708"],"URL":"https:\/\/doi.org\/10.3390\/toxics10110708","relation":{},"ISSN":["2305-6304"],"issn-type":[{"type":"electronic","value":"2305-6304"}],"subject":[],"published":{"date-parts":[[2022,11,20]]}}}