{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:16:44Z","timestamp":1760145404939,"version":"build-2065373602"},"reference-count":50,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T00:00:00Z","timestamp":1722038400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42171060","CARS-38"],"award-info":[{"award-number":["42171060","CARS-38"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015335","name":"Modern Agricultural Industry Technology System","doi-asserted-by":"publisher","award":["42171060","CARS-38"],"award-info":[{"award-number":["42171060","CARS-38"]}],"id":[{"id":"10.13039\/501100015335","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxics"],"abstract":"<jats:p>Molybdenum (Mo), an essential mineral, plays a key role in the vital activity of the organism. However, excess Mo in the forage will cause loss of appetite, diarrhea, emaciation, bone injury, joint abnormalities, and anemia in animals. In order to study molybdenosis in the Procapra picticaudata in the animal rescue center, samples of soils, forages, blood, and liver were collected. The mineral contents of all samples were determined, and the blood parameters were also measured. The results showed that the Mo level in the soil and forage in the animal rescue center was significantly higher than that in healthy pastures (p &lt; 0.01). The Mo concentrations in the blood and liver in the P. picticaudata from the animal rescue center were also noticeably higher than those in healthy animals (p &lt; 0.01). The level of Cu in the blood and liver were noticeably lower than those in healthy P. picticaudata (p &lt; 0.01). The superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), total antioxidant capacity (T-AOC), and catalase (CAT) were significantly lower than those in healthy animals. Supplementing copper sulfate (CuSO4) could significantly decrease the Mo content in the blood, and cure molybdenosis. In summary, the excessive Mo content in the soil and forage in the animal rescue center had greatly affected physiological parameters and antioxidant capacity. It is likely that the molybdenosis of the P. picticaudata is caused by the high Mo contents in soils and forages. CuSO4 may alleviate molybdenosis in P. picticaudata.<\/jats:p>","DOI":"10.3390\/toxics12080546","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T12:27:43Z","timestamp":1722256063000},"page":"546","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Copper Sulfate Supplementation Alleviates Molybdenosis in the Tibetan Gazelles in the Qinghai Lake Basin"],"prefix":"10.3390","volume":"12","author":[{"given":"Guangyang","family":"Liu","sequence":"first","affiliation":[{"name":"School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyun","family":"Shen","sequence":"additional","affiliation":[{"name":"School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621000, China"},{"name":"School of Life Sciences, Liaocheng University, Liaocheng 252000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1046\/j.1365-3008.2000.00108.x","article-title":"Population declines of Przewalski\u2019s gazelle around Qinghai Lake, China","volume":"34","author":"Jiang","year":"2000","journal-title":"Oryx"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"67","DOI":"10.15244\/pjoes\/104661","article-title":"Distribution characteristics of selenium nutrition on the natural habitat of Przewalski\u2019s gazelle","volume":"29","author":"Chi","year":"2019","journal-title":"Pol. 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