{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T14:05:46Z","timestamp":1792850746224,"version":"4.5.0"},"reference-count":38,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Zhejiang Provincial Natural Science Foundation of China","award":["LQ23H260007"],"award-info":[{"award-number":["LQ23H260007"]}]},{"name":"Zhejiang Provincial Natural Science Foundation of China","award":["Y202249200"],"award-info":[{"award-number":["Y202249200"]}]},{"name":"Zhejiang Provincial Natural Science Foundation of China","award":["KYYB202202"],"award-info":[{"award-number":["KYYB202202"]}]},{"name":"Scientific Research Fund of Zhejiang Provincial Education Department","award":["LQ23H260007"],"award-info":[{"award-number":["LQ23H260007"]}]},{"name":"Scientific Research Fund of Zhejiang Provincial Education Department","award":["Y202249200"],"award-info":[{"award-number":["Y202249200"]}]},{"name":"Scientific Research Fund of Zhejiang Provincial Education Department","award":["KYYB202202"],"award-info":[{"award-number":["KYYB202202"]}]},{"name":"Basic Scientific Research Funds of Department of Education of Zhejiang Province","award":["LQ23H260007"],"award-info":[{"award-number":["LQ23H260007"]}]},{"name":"Basic Scientific Research Funds of Department of Education of Zhejiang Province","award":["Y202249200"],"award-info":[{"award-number":["Y202249200"]}]},{"name":"Basic Scientific Research Funds of Department of Education of Zhejiang Province","award":["KYYB202202"],"award-info":[{"award-number":["KYYB202202"]}]},{"name":"Key Discipline of Zhejiang Province in Public Health and Preventive Medicine (First Class, Category A)","award":["LQ23H260007"],"award-info":[{"award-number":["LQ23H260007"]}]},{"name":"Key Discipline of Zhejiang Province in Public Health and Preventive Medicine (First Class, Category A)","award":["Y202249200"],"award-info":[{"award-number":["Y202249200"]}]},{"name":"Key Discipline of Zhejiang Province in Public Health and Preventive Medicine (First Class, Category A)","award":["KYYB202202"],"award-info":[{"award-number":["KYYB202202"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxics"],"abstract":"<jats:p>Air pollution has become a serious public health problem and there is evidence that air pollution affects the incidence of allergic rhinitis. To further investigate the effect of ambient air pollutants on the severity of allergic rhinitis symptoms, a prospective follow-up study in patients with allergic rhinitis was conducted. A total of 167 allergic rhinitis patients with a mean age of 35.4 years, who were visiting the hospital, were enrolled. The daily symptom severity of allergic rhinitis and the concentrations of six air pollutants, including PM2.5, PM10, SO2, CO, O3 and NO2, were collected through follow-up investigations. The impact of ambient air pollutants on symptom severity was assessed via multi-pollutant models. Among several typical ambient air pollutants, we observed correlations of allergic rhinitis symptoms with PM2.5, PM10, CO, SO2 and NO2, whereas O3 showed no such correlation. Specifically, PM2.5 and PM10 were significantly associated with sneezing and nasal blockage. NO2 was significantly correlated with symptoms of rhinorrhea, itchy nose and itchy eyes. CO was significantly linked to sneezing and nasal blockage symptoms. These air pollutants not only had a direct impact on allergic rhinitis symptoms but also exhibited a lagging effect. This study indicates that short-term exposure to air pollutants is associated with exacerbation of nasal symptoms in patients with allergic rhinitis, leading to a decline in their quality of life.<\/jats:p>","DOI":"10.3390\/toxics12090663","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T07:59:46Z","timestamp":1726041586000},"page":"663","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The Impact of Ambient Air Pollution on Allergic Rhinitis Symptoms: A Prospective Follow-Up Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Wen","family":"Sun","sequence":"first","affiliation":[{"name":"School of Public Health, Hangzhou Medical College, 182 Tianmushan Road, Xihu District, Hangzhou 310013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan","family":"Ding","sequence":"additional","affiliation":[{"name":"School of Public Health, Hangzhou Medical College, 182 Tianmushan Road, Xihu District, Hangzhou 310013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoying","family":"Jiang","sequence":"additional","affiliation":[{"name":"School of Public Health, Hangzhou Medical College, 182 Tianmushan Road, Xihu District, Hangzhou 310013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinliang","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Public Health, Hangzhou Medical College, 182 Tianmushan Road, Xihu District, Hangzhou 310013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlan","family":"Jiang","sequence":"additional","affiliation":[{"name":"The Second School of Clinical Medicine, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou 310053, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2698-1807","authenticated-orcid":false,"given":"Huadong","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Public Health, Hangzhou Medical College, 182 Tianmushan Road, Xihu District, Hangzhou 310013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2024, April 24). 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