{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T23:55:43Z","timestamp":1792886143109,"version":"4.5.0"},"reference-count":313,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T00:00:00Z","timestamp":1727568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"ANR","award":["ANR-21-CE34-0022"],"award-info":[{"award-number":["ANR-21-CE34-0022"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxics"],"abstract":"<jats:p>Phenols, parabens, and phthalates (PPPs) are suspected or known endocrine disruptors. They are used in consumer products that pregnant women and their progeny are exposed to daily through the placenta, which could affect offspring health. This review aims to compile data from cohort studies and in vitro and in vivo models to provide a summary regarding placental transfer, fetoplacental development, and the predisposition to adult diseases resulting from maternal exposure to PPPs during the gestational period. In humans, using the concentration of pollutants in maternal urine, and taking the offspring sex into account, positive or negative associations have been observed concerning placental or newborn weight, children\u2019s BMI, blood pressure, gonadal function, or age at puberty. In animal models, without taking sex into account, alterations of placental structure and gene expression linked to hormones or DNA methylation were related to phenol exposure. At the postnatal stage, pollutants affect the bodyweight, the carbohydrate metabolism, the cardiovascular system, gonadal development, the age of puberty, sex\/thyroid hormones, and gamete quality, but these effects depend on the age and sex. Future challenges will be to explore the effects of pollutants in mixtures using models and to identify the early signatures of in utero exposure capable of predicting the health trajectory of the offspring.<\/jats:p>","DOI":"10.3390\/toxics12100710","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T07:19:37Z","timestamp":1727680777000},"page":"710","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Short-Half-Life Chemicals: Maternal Exposure and Offspring Health Consequences\u2014The Case of Synthetic Phenols, Parabens, and Phthalates"],"prefix":"10.3390","volume":"12","author":[{"given":"Delphine","family":"Rousseau-Ralliard","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, INRAE, BREED, 78350 Jouy-en-Josas, France"},{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, BREED, 94700 Maisons-Alfort, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne","family":"Bozec","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, INRAE, BREED, 78350 Jouy-en-Josas, France"},{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, BREED, 94700 Maisons-Alfort, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6027-1484","authenticated-orcid":false,"given":"Marion","family":"Ouidir","sequence":"additional","affiliation":[{"name":"University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team of Environmental Epidemiology Applied to Development and Respiratory Health, Institute for Advanced Biosciences, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3509-4202","authenticated-orcid":false,"given":"Nicolas","family":"Jovanovic","sequence":"additional","affiliation":[{"name":"University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team of Environmental Epidemiology Applied to Development and Respiratory Health, Institute for Advanced Biosciences, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Gayrard","sequence":"additional","affiliation":[{"name":"ToxAlim (Research Center in Food Toxicology), Universit\u00e9 de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31062 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namya","family":"Mellouk","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, INRAE, BREED, 78350 Jouy-en-Josas, France"},{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, BREED, 94700 Maisons-Alfort, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-No\u00eblle","family":"Dieudonn\u00e9","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, INRAE, BREED, 78350 Jouy-en-Josas, France"},{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, BREED, 94700 Maisons-Alfort, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Picard-Hagen","sequence":"additional","affiliation":[{"name":"ToxAlim (Research Center in Food Toxicology), Universit\u00e9 de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31062 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2301-3854","authenticated-orcid":false,"given":"Maria-Jos\u00e9","family":"Flores-Sanabria","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, INRAE, BREED, 78350 Jouy-en-Josas, France"},{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, BREED, 94700 Maisons-Alfort, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Jammes","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, INRAE, BREED, 78350 Jouy-en-Josas, France"},{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, BREED, 94700 Maisons-Alfort, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Philippat","sequence":"additional","affiliation":[{"name":"University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team of Environmental Epidemiology Applied to Development and Respiratory Health, Institute for Advanced Biosciences, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1559-5476","authenticated-orcid":false,"given":"Anne","family":"Couturier-Tarrade","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, INRAE, BREED, 78350 Jouy-en-Josas, France"},{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, BREED, 94700 Maisons-Alfort, 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(2022). Exposure to Bisphenol A Substitutes, Bisphenol S and Bisphenol F, and Its Association with Developing Obesity and Diabetes Mellitus: A Narrative Review. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph192315918"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"105678","DOI":"10.1016\/j.envint.2020.105678","article-title":"Exposure to phenols during pregnancy and the first year of life in a new type of couple-child cohort relying on repeated urine biospecimens","volume":"139","author":"Rolland","year":"2020","journal-title":"Environ. Int."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"119346","DOI":"10.1016\/j.envpol.2022.119346","article-title":"Genotoxic potential of bisphenol A: A review","volume":"306","author":"Kyzek","year":"2022","journal-title":"Environ. Pollut."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Oliviero, F., Marmugi, A., Vigui\u00e9, C., Gayrard, V., Picard-Hagen, N., and Mselli-Lakhal, L. (2022). Are BPA Substitutes as Obesogenic as BPA?. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23084238"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.3390\/ijerph120505657","article-title":"Triclosan: Current status, occurrence, environmental risks and bioaccumulation potential","volume":"12","author":"Dhillon","year":"2015","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0278-6915(99)00164-7","article-title":"Percutaneous penetration and dermal metabolism of triclosan (2,4, 4\u2032-trichloro-2\u2032-hydroxydiphenyl ether)","volume":"38","author":"Moss","year":"2000","journal-title":"Food Chem. Toxicol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1080\/10937404.2017.1399306","article-title":"Triclosan exposure, transformation, and human health effects","volume":"20","author":"Weatherly","year":"2017","journal-title":"J. Toxicol. Environ. Health Part B Crit. Rev."},{"key":"ref_8","first-page":"25119","article-title":"Comprehensive insight into triclosan-from widespread occurrence to health outcomes","volume":"30","year":"2023","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.envpol.2015.07.001","article-title":"Reproductive endocrine-disrupting effects of triclosan: Population exposure, present evidence and potential mechanisms","volume":"206","author":"Wang","year":"2015","journal-title":"Environ. Pollut."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1080\/10937404.2017.1281181","article-title":"Is Triclosan a neurotoxic agent?","volume":"20","author":"Ruszkiewicz","year":"2017","journal-title":"J. Toxicol. Environ. Health Part B Crit. Rev."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1186\/s40064-016-3287-x","article-title":"Triclosan in water, implications for human and environmental health","volume":"5","author":"Olaniyan","year":"2016","journal-title":"SpringerPlus"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3109\/10408444.2014.910754","article-title":"Critical analysis of endocrine disruptive activity of triclosan and its relevance to human exposure through the use of personal care products","volume":"44","author":"Witorsch","year":"2014","journal-title":"Crit. Rev. Toxicol."},{"key":"ref_13","unstructured":"Juncker, J.-C. (2016). Commission Impementing Decision Not Approving Triclosan as an Existing Active Substance for Use in Biocidal Products for Product-Type 1, Union European. 528\/2012."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.mce.2018.03.014","article-title":"Parabens and their effects on the endocrine system","volume":"474","author":"Nowak","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Hager, E., Chen, J., and Zhao, L. (2022). Minireview: Parabens Exposure and Breast Cancer. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19031873"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Giuliani, A., Zuccarini, M., Cichelli, A., Khan, H., and Reale, M. (2020). Critical Review on the Presence of Phthalates in Food and Evidence of Their Biological Impact. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17165655"},{"key":"ref_17","first-page":"803","article-title":"What are the sources of exposure to eight frequently used phthalic acid esters in Europeans?","volume":"26","author":"Wormuth","year":"2006","journal-title":"Risk Anal. Off. Publ. Soc. Risk Anal."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Wang, Y., Zhu, H., and Kannan, K. (2019). A Review of Biomonitoring of Phthalate Exposures. Toxics, 7.","DOI":"10.3390\/toxics7020021"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"117650","DOI":"10.1016\/j.envpol.2021.117650","article-title":"Pre- and early post-natal exposure to phthalates and DINCH in a new type of mother-child cohort relying on within-subject pools of repeated urine samples","volume":"287","author":"Philippat","year":"2021","journal-title":"Environ. Pollut."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"EFSA (2011). Report on the development of a Food Classification and Description System for exposure assessment and guidance on its implementation and use. EFSA J., 9, 2489.","DOI":"10.2903\/j.efsa.2011.2489"},{"key":"ref_21","unstructured":"EFSA (2006). Commission directive 2006\/141\/EC of 22 December 2006 on infant formulae and follow-on formulae and amending Directive 1999\/21\/EC. EFSA J., 4, 4544."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"615068","DOI":"10.1100\/2012\/615068","article-title":"Human elimination of phthalate compounds: Blood, urine, and sweat (BUS) study","volume":"2012","author":"Genuis","year":"2012","journal-title":"Sci. World J."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/0140-6736(93)91224-A","article-title":"Fetal nutrition and cardiovascular disease in adult life","volume":"341","author":"Barker","year":"1993","journal-title":"Lancet"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.taap.2007.12.008","article-title":"Human exposure to bisphenol A by biomonitoring: Methods, results and assessment of environmental exposures","volume":"228","author":"Dekant","year":"2008","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.envint.2015.06.008","article-title":"Pharmacokinetics of bisphenol A in humans following a single oral administration","volume":"83","author":"Thayer","year":"2015","journal-title":"Environ. Int."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"105644","DOI":"10.1016\/j.envint.2020.105644","article-title":"Toxicokinetics of bisphenol-S and its glucuronide in plasma and urine following oral and dermal exposure in volunteers for the interpretation of biomonitoring data","volume":"138","author":"Khmiri","year":"2020","journal-title":"Environ. Int."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.envint.2017.11.020","article-title":"Pharmacokinetics of bisphenol S in humans after single oral administration","volume":"112","author":"Oh","year":"2018","journal-title":"Environ. Int."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1080\/15287390600631706","article-title":"Pharmacokinetics of triclosan following oral ingestion in humans","volume":"69","author":"Odham","year":"2006","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/jat.2550150207","article-title":"Pharmacokinetics of benzophenone-3 after oral exposure in male rats","volume":"15","author":"Kadry","year":"1995","journal-title":"J. Appl. Toxicol. JAT"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.tox.2008.02.009","article-title":"Toxicokinetics and metabolisms of benzophenone-type UV filters in rats","volume":"248","author":"Jeon","year":"2008","journal-title":"Toxicology"},{"key":"ref_31","first-page":"788","article-title":"Metabolism of benzophenone-3 in rats","volume":"21","author":"Okereke","year":"1993","journal-title":"Drug Metab. Dispos. Biol. Fate Chem."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"568","DOI":"10.2133\/dmpk.DMPK-10-RG-013","article-title":"Metabolism of parabens (4-hydroxybenzoic acid esters) by hepatic esterases and UDP-glucuronosyltransferases in man","volume":"25","author":"Abbas","year":"2010","journal-title":"Drug Metab. Pharmacokinet."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/mnfr.201000121","article-title":"Assessing exposure to phthalates\u2014The human biomonitoring approach","volume":"55","author":"Wittassek","year":"2011","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1530\/REP-13-0522","article-title":"Human urinary excretion of non-persistent environmental chemicals: An overview of Danish data collected between 2006 and 2012","volume":"147","author":"Frederiksen","year":"2014","journal-title":"Reproduction"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"110275","DOI":"10.1016\/j.envres.2020.110275","article-title":"Comparison of strategies to efficiently combine repeated urine samples in biomarker-based studies","volume":"192","author":"Philippat","year":"2021","journal-title":"Environ. Res."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"17002","DOI":"10.1289\/EHP3523","article-title":"Prenatal Exposure to Select Phthalates and Phenols and Associations with Fetal and Placental Weight among Male Births in the EDEN Cohort (France)","volume":"127","author":"Philippat","year":"2019","journal-title":"Environ. Health Perspect."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1289\/ehp.1206335","article-title":"Prenatal exposure to environmental phenols: Concentrations in amniotic fluid and variability in urinary concentrations during pregnancy","volume":"121","author":"Philippat","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1530\/REP-13-0461","article-title":"Current exposure of 200 pregnant Danish women to phthalates, parabens and phenols","volume":"147","author":"Frederiksen","year":"2014","journal-title":"Reproduction"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"106697","DOI":"10.1016\/j.envint.2021.106697","article-title":"Associations between a mixture of phenols and phthalates and child behaviour in a French mother-child cohort with repeated assessment of exposure","volume":"156","author":"Guilbert","year":"2021","journal-title":"Environ. Int."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00204-003-0522-3","article-title":"Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHP","volume":"78","author":"Koch","year":"2004","journal-title":"Arch. Toxicol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3945\/ajcn.115.121954","article-title":"Feasibility of collecting 24-h urine to monitor sodium intake in the National Health and Nutrition Examination Survey","volume":"104","author":"Terry","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1007\/s00204-015-1636-0","article-title":"Metabolism and elimination of methyl, iso- and n-butyl paraben in human urine after single oral dosage","volume":"90","author":"Moos","year":"2016","journal-title":"Arch. Toxicol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"104917","DOI":"10.1016\/j.envint.2019.104917","article-title":"Pharmacokinetic profile of propyl paraben in humans after oral administration","volume":"130","author":"Shin","year":"2019","journal-title":"Environ. Int."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1007\/s00204-012-0908-1","article-title":"Di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) metabolism in a human volunteer after single oral doses","volume":"86","author":"Koch","year":"2012","journal-title":"Arch. Toxicol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1080\/02652030110050113","article-title":"A biomarker approach to measuring human dietary exposure to certain phthalate diesters","volume":"18","author":"Anderson","year":"2001","journal-title":"Food Addit. Contam."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ijheh.2006.11.008","article-title":"Di-iso-nonylphthalate (DINP) metabolites in human urine after a single oral dose of deuterium-labelled DINP","volume":"210","author":"Koch","year":"2007","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.yrtph.2009.09.001","article-title":"Derivation of Biomonitoring Equivalents for di(2-ethylhexyl)phthalate (CAS No. 117-81-7)","volume":"55","author":"Aylward","year":"2009","journal-title":"Regul. Toxicol. Pharmacol. RTP"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1098\/rstb.2008.0208","article-title":"Human body burdens of chemicals used in plastic manufacture","volume":"364","author":"Koch","year":"2009","journal-title":"Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408444.2011.599366","article-title":"Challenges in the application of quantitative approaches in risk assessment: A case study with di-(2-ethylhexyl)phthalate","volume":"41","author":"Gentry","year":"2011","journal-title":"Crit. Rev. Toxicol."},{"key":"ref_50","first-page":"33","article-title":"Drug disposition and effects in the fetus","volume":"15","author":"Rurak","year":"1991","journal-title":"J. Dev. Physiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/978-3-642-10324-7_2","article-title":"Species differences in pharmacokinetics and pharmacodynamics","volume":"199","author":"Toutain","year":"2010","journal-title":"Handb. Exp. Pharmacol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"117006","DOI":"10.1289\/EHP8957","article-title":"Use of Mixture Dosing and Nonlinear Mixed Effect Modeling of Eight Environmental Contaminants in Rabbits to Improve Extrapolation Value of Toxicokinetic Data","volume":"129","author":"Gayrard","year":"2021","journal-title":"Environ. Health Perspect."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.placenta.2022.05.003","article-title":"Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability","volume":"126","author":"Schneider","year":"2022","journal-title":"Placenta"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"105408","DOI":"10.1016\/j.envint.2019.105408","article-title":"Phthalate exposure and neurodevelopment: A systematic review and meta-analysis of human epidemiological evidence","volume":"137","author":"Radke","year":"2020","journal-title":"Environ. Int."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Corbel, T., Gayrard, V., Vigui\u00e9, C., Puel, S., Lacroix, M.Z., Toutain, P.L., and Picard-Hagen, N. (2013). Bisphenol A disposition in the sheep maternal-placental-fetal unit: Mechanisms determining fetal internal exposure. Biol. Reprod., 89.","DOI":"10.1095\/biolreprod.112.106369"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"R1123","DOI":"10.1152\/ajpregu.00391.2017","article-title":"Improving pregnancy outcomes in humans through studies in sheep","volume":"315","author":"Morrison","year":"2018","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.theriogenology.2007.09.021","article-title":"The pregnant sheep as a model for human pregnancy","volume":"69","author":"Barry","year":"2008","journal-title":"Theriogenology"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"130213","DOI":"10.1016\/j.chemosphere.2021.130213","article-title":"Comparison of the materno-fetal transfer of fifteen structurally related bisphenol analogues using an ex vivo human placental perfusion model","volume":"276","author":"Lacroix","year":"2021","journal-title":"Chemosphere"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.reprotox.2014.06.001","article-title":"Bidirectional placental transfer of Bisphenol A and its main metabolite, Bisphenol A-Glucuronide, in the isolated perfused human placenta","volume":"47","author":"Corbel","year":"2014","journal-title":"Reprod. Toxicol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.chemosphere.2019.01.065","article-title":"Is bisphenol S a safer alternative to bisphenol A in terms of potential fetal exposure ? Placental transfer across the perfused human placenta","volume":"221","author":"Grandin","year":"2019","journal-title":"Chemosphere"},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"G\u00e9ly, C.A., Picard-Hagen, N., Chassan, M., Garrigues, J.C., Gayrard, V., and Lacroix, M.Z. (2023). Contribution of Reliable Chromatographic Data in QSAR for Modelling Bisphenol Transport across the Human Placenta Barrier. Molecules, 28.","DOI":"10.3390\/molecules28020500"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.envint.2015.10.006","article-title":"Bisphenol A glucuronide deconjugation is a determining factor of fetal exposure to bisphenol A","volume":"86","author":"Gauderat","year":"2016","journal-title":"Environ. Int."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.envint.2018.08.019","article-title":"Bisphenol S instead of Bisphenol A: Toxicokinetic investigations in the ovine materno-feto-placental unit","volume":"120","author":"Grandin","year":"2018","journal-title":"Environ. Int."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.chemosphere.2018.12.109","article-title":"Toxicokinetics of bisphenol A, bisphenol S, and bisphenol F in a pregnancy sheep model","volume":"220","author":"Gingrich","year":"2019","journal-title":"Chemosphere"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.placenta.2021.09.010","article-title":"Placental transport of parabens studied using an ex-vivo human perfusion model","volume":"115","author":"Andersen","year":"2021","journal-title":"Placenta"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/toxsci\/kfh294","article-title":"Pharmacokinetics of dibutylphthalate in pregnant rats","volume":"82","author":"Fennell","year":"2004","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1093\/toxsci\/45.2.212","article-title":"Assessment of the developmental toxicity, metabolism, and placental transfer of Di-n-butyl phthalate administered to pregnant rats","volume":"45","author":"Saillenfait","year":"1998","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1002\/jps.2600640819","article-title":"Maternal-fetal transfer of 14C-di-2-ethylhexyl phthalate and 14C-diethyl phthalate in rats","volume":"64","author":"Singh","year":"1975","journal-title":"J. Pharm. Sci."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.toxlet.2005.05.006","article-title":"Pharmacokinetics of monobutylphthalate, the active metabolite of di-n-butylphthalate, in pregnant rats","volume":"159","author":"Kremer","year":"2005","journal-title":"Toxicol. Lett."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.tox.2005.08.013","article-title":"Urinary and amniotic fluid levels of phthalate monoesters in rats after the oral administration of di(2-ethylhexyl) phthalate and di-n-butyl phthalate","volume":"217","author":"Calafat","year":"2006","journal-title":"Toxicology"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1080\/10915810701352721","article-title":"Transplacental transfer of monomethyl phthalate and mono(2-ethylhexyl) phthalate in a human placenta perfusion system","volume":"26","author":"Mose","year":"2007","journal-title":"Int. J. Toxicol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.reprotox.2006.08.006","article-title":"Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood","volume":"23","author":"Mose","year":"2007","journal-title":"Reprod. Toxicol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1080\/10807039.2017.1381831","article-title":"Application of a novel mass spectrometric (MS) method to examine exposure to Bisphenol-A and common substitutes in a maternal fetal cohort","volume":"24","author":"Ihde","year":"2018","journal-title":"Hum. Ecol. Risk Assess. HERA"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1021\/acs.est.6b05718","article-title":"Bisphenol A Metabolites and Bisphenol S in Paired Maternal and Cord Serum","volume":"51","author":"Liu","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1289\/ehp.1409190","article-title":"Exposure to Bisphenol A and Phthalates during Pregnancy and Ultrasound Measures of Fetal Growth in the INMA-Sabadell Cohort","volume":"124","author":"Casas","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.envint.2017.12.011","article-title":"Environmental phenol associations with ultrasound and delivery measures of fetal growth","volume":"112","author":"Ferguson","year":"2018","journal-title":"Environ. Int."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12940-020-00635-5","article-title":"Weight and head circumference at birth in function of placental paraben load in Belgium: An ENVIRONAGE birth cohort study","volume":"19","author":"Vrijens","year":"2020","journal-title":"Environ. Health"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.envres.2017.09.012","article-title":"Prenatal phthalate exposure and placental size and shape at birth: A birth cohort study","volume":"160","author":"Zhu","year":"2018","journal-title":"Environ. Res."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"156498","DOI":"10.1016\/j.scitotenv.2022.156498","article-title":"Relationship of individual and mixed prenatal phthalate exposure with placental structure and efficiency in the prospective Ma\u2019anshan Birth Cohort Study","volume":"838","author":"Gao","year":"2022","journal-title":"Sci. Total Environ."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.envres.2018.11.022","article-title":"Placental weight in relation to maternal and paternal preconception and prenatal urinary phthalate metabolite concentrations among subfertile couples","volume":"169","author":"Mustieles","year":"2019","journal-title":"Environ. Res."},{"key":"ref_81","doi-asserted-by":"crossref","unstructured":"Huang, Y., Li, J., Garcia, J.M., Lin, H., Wang, Y., Yan, P., Wang, L., Tan, Y., Luo, J., and Qiu, Z. (2014). Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0087430"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"hoae018","DOI":"10.1093\/hropen\/hoae018","article-title":"Associations between synthetic phenols, phthalates, and placental growth\/function: A longitudinal cohort with exposure assessment in early pregnancy","volume":"2024","author":"Jovanovic","year":"2024","journal-title":"Hum. Reprod. Open"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"108584","DOI":"10.1016\/j.envint.2024.108584","article-title":"Analyzing the impact of phthalate and DINCH exposure on fetal growth in a cohort with repeated urine collection","volume":"186","author":"Ouidir","year":"2024","journal-title":"Environ. Int."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.scitotenv.2017.08.207","article-title":"Relationship between maternal phthalate exposure and offspring size at birth","volume":"612","author":"Zhu","year":"2018","journal-title":"Sci. Total Environ."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.envres.2014.04.032","article-title":"The impact of first trimester phthalate and phenol exposure on IGF2\/H19 genomic imprinting and birth outcomes","volume":"133","author":"LaRocca","year":"2014","journal-title":"Environ. Res."},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Zhao, Y., Chen, J., Wang, X., Song, Q., Xu, H.H., and Zhang, Y.H. (2016). Third trimester phthalate exposure is associated with DNA methylation of growth-related genes in human placenta. Sci. Rep., 6.","DOI":"10.1038\/srep33449"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/em.21916","article-title":"Prenatal phthalate exposure, infant growth, and global DNA methylation of human placenta","volume":"56","author":"Zhao","year":"2015","journal-title":"Environ. Mol. Mutagen."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"5123","DOI":"10.1093\/nar\/gkw124","article-title":"DNA methylation in human epigenomes depends on local topology of CpG sites","volume":"44","author":"Dodd","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"ref_89","doi-asserted-by":"crossref","unstructured":"Grindler, N.M., Vanderlinden, L., Karthikraj, R., Kannan, K., Teal, S., Polotsky, A.J., Powell, T.L., Yang, I.V., and Jansson, T. (2018). Exposure to Phthalate, an Endocrine Disrupting Chemical, Alters the First Trimester Placental Methylome and Transcriptome in Women. Sci. Rep., 8.","DOI":"10.1038\/s41598-018-24505-w"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"144115","DOI":"10.1016\/j.scitotenv.2020.144115","article-title":"Prenatal exposure to a wide range of environmental chemicals and child behaviour between 3 and 7 years of age\u2014An exposome-based approach in 5 European cohorts","volume":"763","author":"Jedynak","year":"2021","journal-title":"Sci. Total Environ."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"107054","DOI":"10.1016\/j.envint.2021.107054","article-title":"Pregnancy exposure to phthalates and DNA methylation in male placenta\u2014An epigenome-wide association study","volume":"160","author":"Jedynak","year":"2022","journal-title":"Environ. Int."},{"key":"ref_92","doi-asserted-by":"crossref","unstructured":"Svendsen, A.J., Gervin, K., Lyle, R., Christiansen, L., Kyvik, K., Junker, P., Nielsen, C., Houen, G., and Tan, Q. (2016). Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study. Front. Immunol., 7.","DOI":"10.3389\/fimmu.2016.00510"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"108763","DOI":"10.1016\/j.envint.2024.108763","article-title":"Epigenetic footprints: Investigating placental DNA methylation in the context of prenatal exposure to phenols and phthalates","volume":"189","author":"Jedynak","year":"2024","journal-title":"Environ. Int."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s43682-024-00027-7","article-title":"Gestational exposure to environmental chemicals and epigenetic alterations in the placenta and cord blood mononuclear cells","volume":"4","author":"Puvvula","year":"2024","journal-title":"Epigenetics. Commun."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"27005","DOI":"10.1289\/EHP7297","article-title":"Bisphenol S and Epidermal Growth Factor Receptor Signaling in Human Placental Cytotrophoblasts","volume":"129","author":"Ticiani","year":"2021","journal-title":"Environ. Health Perspect."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1007\/s00204-023-03444-0","article-title":"Mono(2-ethylhexyl) phthalate induces transcriptomic changes in placental cells based on concentration, fetal sex, and trophoblast cell type","volume":"97","author":"Lapehn","year":"2023","journal-title":"Arch. Toxicol."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"27003","DOI":"10.1289\/EHP3730","article-title":"The Role of Peroxisome Proliferator\u2013Activated Receptor Gamma (PPAR\u03b3) in Mono(2-ethylhexyl) Phthalate (MEHP)-Mediated Cytotrophoblast Differentiation","volume":"127","author":"Shoaito","year":"2019","journal-title":"Environ. Health Perspect."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"107010","DOI":"10.1289\/EHP1539","article-title":"An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells","volume":"125","author":"Adibi","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1210\/endo-118-4-1567","article-title":"3rd. Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae","volume":"118","author":"Kliman","year":"1986","journal-title":"Endocrinology"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1093\/biolre\/ioac044","article-title":"Sex-specific effects of bisphenol A on the signaling pathway of ESRRG in the human placenta","volume":"106","author":"Zou","year":"2022","journal-title":"Biol. Reprod."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"103368","DOI":"10.1016\/j.jri.2021.103368","article-title":"Enhancement of placental inflammation by Dibutyl Phthalate","volume":"147","author":"Alsubaie","year":"2021","journal-title":"J. Reprod. Immunol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.mce.2003.03.001","article-title":"Endocrine cell lines from the placenta","volume":"228","author":"Sullivan","year":"2004","journal-title":"Mol. Cell Endocrinol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"83","DOI":"10.5115\/acb.20.234","article-title":"JEG-3 placental cells in toxicology studies: A promising tool to reveal pregnancy disorders","volume":"54","author":"Olivier","year":"2021","journal-title":"Anat. Cell Biol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1006\/excr.1993.1139","article-title":"Establishment and characterization of first trimester human trophoblast cells with extended lifespan","volume":"206","author":"Graham","year":"1993","journal-title":"Exp. Cell Res."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.reprotox.2022.10.001","article-title":"Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP\/PKA signaling pathway in human trophoblastic HTR-8\/Svneo cells","volume":"114","author":"Gu","year":"2022","journal-title":"Reprod. Toxicol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/0014-4827(90)90310-7","article-title":"Modulators of cyclic AMP metabolism induce syncytiotrophoblast formation in vitro","volume":"186","author":"Wice","year":"1990","journal-title":"Exp. Cell Res."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1530\/REP-10-0221","article-title":"The choriocarcinoma cell line BeWo: Syncytial fusion and expression of syncytium-specific proteins","volume":"140","author":"Orendi","year":"2010","journal-title":"Reproduction"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1016\/j.placenta.2014.12.015","article-title":"Review: An overview of molecular events occurring in human trophoblast fusion","volume":"36","author":"Gerbaud","year":"2015","journal-title":"Placenta"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.placenta.2021.02.022","article-title":"Molecular characteristics of established trophoblast-derived cell lines","volume":"108","author":"Pastuschek","year":"2021","journal-title":"Placenta"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s10616-017-0142-z","article-title":"Co-culture of JEG-3, BeWo and syncBeWo cell lines with adrenal H295R cell line: An alternative model for examining endocrine and metabolic properties of the fetoplacental unit","volume":"70","author":"Drwal","year":"2018","journal-title":"Cytotechnology"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1093\/molehr\/gaz061","article-title":"Transcriptomic profiling of trophoblast fusion using BeWo and JEG-3 cell lines","volume":"25","author":"Msheik","year":"2019","journal-title":"Mol. Hum. Reprod."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"113051","DOI":"10.1016\/j.ecoenv.2021.113051","article-title":"Effects of triclosan exposure on placental extravillous trophoblast motility, relevant IGF2\/H19 signaling and DNA methylation-related enzymes of HTR-8\/SVneo cell line","volume":"228","author":"Ma","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1289\/ehp.1409049","article-title":"Exposure to Endocrine-Disrupting Chemicals during Pregnancy and Weight at 7 Years of Age: A Multi-pollutant Approach","volume":"123","author":"Martinez","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.placenta.2019.12.013","article-title":"HTR-8\/SVneo: A model for epithelial to mesenchymal transition in the human placenta","volume":"90","author":"Msheik","year":"2020","journal-title":"Placenta"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"635364","DOI":"10.1155\/2014\/635364","article-title":"Bisphenol A alters \u03b2-hCG and MIF release by human placenta: An in vitro study to understand the role of endometrial cells","volume":"2014","author":"Mannelli","year":"2014","journal-title":"Mediat. Inflamm."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.reprotox.2010.02.007","article-title":"Placental transport and in vitro effects of Bisphenol A","volume":"30","author":"Sorda","year":"2010","journal-title":"Reprod. Toxicol."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.reprotox.2015.03.001","article-title":"Bisphenol A disrupts gene expression in human placental trophoblast cells","volume":"53","author":"Rajakumar","year":"2015","journal-title":"Reprod. Toxicol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.taap.2009.09.005","article-title":"Toxic effects of low doses of Bisphenol-A on human placental cells","volume":"241","author":"Benachour","year":"2009","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Wang, X.K., Agarwal, M., Parobchak, N., Rosen, A., Vetrano, A.M., Srinivasan, A., Wang, B., and Rosen, T. (2016). Mono-(2-Ethylhexyl) Phthalate Promotes Pro-Labor Gene Expression in the Human Placenta. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0147013"},{"key":"ref_120","doi-asserted-by":"crossref","unstructured":"de Aguiar Greca, S.C., Kyrou, I., Pink, R., Randeva, H., Grammatopoulos, D., Silva, E., and Karteris, E. (2020). Involvement of the Endocrine-Disrupting Chemical Bisphenol A (BPA) in Human Placentation. J. Clin. Med., 9.","DOI":"10.3390\/jcm9020405"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1021\/acs.chemrestox.5b00093","article-title":"Bisphenol A increases BeWo trophoblast survival in stress-induced paradigms through regulation of oxidative stress and apoptosis","volume":"28","author":"Ponniah","year":"2015","journal-title":"Chem. Res. Toxicol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"60805","DOI":"10.1007\/s11356-023-26850-4","article-title":"BPA induces placental trophoblast proliferation inhibition and fetal growth restriction by inhibiting the expression of SRB1","volume":"30","author":"Cao","year":"2023","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.reprotox.2019.07.001","article-title":"Effects of Bisphenol A on endogenous retroviral envelopes expression and trophoblast fusion in BeWo cells","volume":"89","author":"Narciso","year":"2019","journal-title":"Reprod. Toxicol."},{"key":"ref_124","first-page":"14355","article-title":"Effect of Bisphenol A on invasion ability of human trophoblastic cell line BeWo","volume":"8","author":"Wang","year":"2015","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"117472","DOI":"10.1016\/j.envpol.2021.117472","article-title":"In vivo and in vitro transcriptomics meta-analyses reveal that BPA may affect TGF-beta signaling regardless of the toxicology system employed","volume":"285","author":"Lu","year":"2021","journal-title":"Environ. Pollut."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1080\/19768354.2020.1711804","article-title":"Ethylparaben induces apoptotic cell death in human placenta BeWo cells via the Caspase-3 pathway","volume":"24","author":"Kim","year":"2020","journal-title":"Anim. Cells Syst."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biochi.2018.03.002","article-title":"Lipidome-wide disturbances of human placental JEG-3 cells by the presence of MEHP","volume":"149","author":"Petit","year":"2018","journal-title":"Biochimie"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1002\/tox.22529","article-title":"Butyl paraben promotes apoptosis in human trophoblast cells through increased oxidative stress-induced endoplasmic reticulum stress","volume":"33","author":"Yang","year":"2018","journal-title":"Environ. Toxicol."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"108339","DOI":"10.1016\/j.reprotox.2023.108339","article-title":"Effects of phthalates on human chorionic trophoblast cells and mouse embryonic development","volume":"116","author":"Wang","year":"2023","journal-title":"Reprod. Toxicol."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"114960","DOI":"10.1016\/j.taap.2020.114960","article-title":"Di-(2-ethylhexyl) phthalate inhibits expression and internalization of transthyretin in human placental trophoblastic cells","volume":"394","author":"Du","year":"2020","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/toxsci\/kfac060","article-title":"Phthalate Exposures and Placental Health in Animal Models and Humans: A Systematic Review","volume":"188","author":"Seymore","year":"2022","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"108446","DOI":"10.1016\/j.reprotox.2023.108446","article-title":"Exposure to di-isononyl phthalate during early pregnancy disrupts decidual angiogenesis and placental development in mice","volume":"120","author":"Bhurke","year":"2023","journal-title":"Reprod. Toxicol."},{"key":"ref_133","doi-asserted-by":"crossref","unstructured":"Barberio, L., Paulesu, L., Canesi, L., Grasselli, E., and Mandal\u00e0, M. (2021). Bisphenol a Interferes with Uterine Artery Features and Impairs Rat Feto-Placental Growth. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22136912"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"125301","DOI":"10.1016\/j.chemosphere.2019.125301","article-title":"Developmental programming: Prenatal bisphenol A treatment disrupts mediators of placental function in sheep","volume":"243","author":"Song","year":"2020","journal-title":"Chemosphere"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"107806","DOI":"10.1016\/j.envint.2023.107806","article-title":"Autophagy attenuates placental apoptosis, oxidative stress and fetal growth restriction in pregnant ewes","volume":"173","author":"Zhang","year":"2023","journal-title":"Environ. Int."},{"key":"ref_136","doi-asserted-by":"crossref","unstructured":"M\u00fcller, J.E., Meyer, N., Santamaria, C.G., Schumacher, A., Luque, E.H., Zenclussen, M.L., Rodriguez, H.A., and Zenclussen, A.C. (2018). Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice. Sci. Rep., 8.","DOI":"10.1038\/s41598-018-27575-y"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1262\/jrd.18171","article-title":"Effects of bisphenol A (BPA) on placentation and survival of the neonates in mice","volume":"53","author":"Tachibana","year":"2007","journal-title":"J. Reprod. Dev."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1002\/jat.3176","article-title":"Bisphenol A affects placental layers morphology and angiogenesis during early pregnancy phase in mice","volume":"35","author":"Tait","year":"2015","journal-title":"J. Appl. Toxicol. JAT"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"51507","DOI":"10.18632\/oncotarget.17882","article-title":"Bisphenol A exposure promotes HTR-8\/SVneo cell migration and impairs mouse placentation involving upregulation of integrin-\u03b21 and MMP-9 and stimulation of MAPK and PI3K signaling pathways","volume":"8","author":"Lan","year":"2017","journal-title":"Oncotarget"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1096\/fj.201800934RRR","article-title":"Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2","volume":"33","author":"Ye","year":"2019","journal-title":"FASEB J."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1262\/jrd.49.329","article-title":"Effects of oral exposure of bisphenol A on mRNA expression of nuclear receptors in murine placentae assessed by DNA microarray","volume":"49","author":"Imanishi","year":"2003","journal-title":"J. Reprod. Dev."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"937","DOI":"10.4161\/epi.6.7.16067","article-title":"Effects of endocrine disruptors on imprinted gene expression in the mouse embryo","volume":"6","author":"Kang","year":"2011","journal-title":"Epigenetics"},{"key":"ref_143","doi-asserted-by":"crossref","unstructured":"Susiarjo, M., Sasson, I., Mesaros, C., and Bartolomei, M.S. (2013). Bisphenol a exposure disrupts genomic imprinting in the mouse. PLoS Genet., 9.","DOI":"10.1371\/journal.pgen.1003401"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.2217\/epi-2021-0339","article-title":"miRNA changes in the mouse placenta due to bisphenol A exposure","volume":"13","author":"Mao","year":"2021","journal-title":"Epigenomics"},{"key":"ref_145","doi-asserted-by":"crossref","unstructured":"Lee, J.H., Ahn, C., Kang, H.Y., Hong, E.J., Hyun, S.H., Choi, K.C., and Jeung, E.B. (2016). Effects of Octylphenol and Bisphenol A on the Metal Cation Transporter Channels of Mouse Placentas. Int. J. Environ. Res. Public Health, 13.","DOI":"10.3390\/ijerph13100965"},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.mce.2003.08.011","article-title":"Maternal-fetal transfer of endocrine disruptors in the induction of Calbindin-D9k mRNA and protein during pregnancy in rat model","volume":"212","author":"Hong","year":"2003","journal-title":"Mol. Cell. Endocrinol."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1262\/jrd.17012","article-title":"Maternal exposure to bisphenol a during late pregnancy resulted in an increase of Calbindin-D9k mRNA and protein in maternal and postnatal rat uteri","volume":"51","author":"Hong","year":"2005","journal-title":"J. Reprod. Dev."},{"key":"ref_148","doi-asserted-by":"crossref","unstructured":"Benincasa, L., Mandal\u00e0, M., Paulesu, L., Barberio, L., and Ietta, F. (2020). Prenatal Nutrition Containing Bisphenol A Affects Placenta Glucose Transfer: Evidence in Rats and Human Trophoblast. Nutrients, 12.","DOI":"10.3390\/nu12051375"},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.taap.2013.03.016","article-title":"Bisphenol A differentially activates protein kinase C isoforms in murine placental tissue","volume":"269","author":"Tan","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1007\/s00204-018-2191-2","article-title":"Gestational bisphenol S impairs placental endocrine function and the fusogenic trophoblast signaling pathway","volume":"92","author":"Gingrich","year":"2018","journal-title":"Arch. Toxicol."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"4642","DOI":"10.1073\/pnas.1919563117","article-title":"Bisphenol A and bisphenol S disruptions of the mouse placenta and potential effects on the placenta-brain axis","volume":"117","author":"Mao","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.reprotox.2012.09.008","article-title":"Disruption of blastocyst implantation by triclosan in mice: Impacts of repeated and acute doses and combination with bisphenol-A","volume":"34","author":"Crawford","year":"2012","journal-title":"Reprod. Toxicol."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.toxlet.2018.05.014","article-title":"Administration of low dose triclosan to pregnant ewes results in placental uptake and reduced estradiol sulfotransferase activity in fetal liver and placenta","volume":"294","author":"Jackson","year":"2018","journal-title":"Toxicol. Lett."},{"key":"ref_154","doi-asserted-by":"crossref","unstructured":"Feng, Y., Zhang, P., Zhang, Z., Shi, J., Jiao, Z., and Shao, B. (2016). Endocrine Disrupting Effects of Triclosan on the Placenta in Pregnant Rats. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0154758"},{"key":"ref_155","doi-asserted-by":"crossref","unstructured":"Cao, X., Hua, X., Wang, X., and Chen, L. (2017). Exposure of pregnant mice to triclosan impairs placental development and nutrient transport. Sci. Rep., 7.","DOI":"10.1038\/srep44803"},{"key":"ref_156","doi-asserted-by":"crossref","unstructured":"Wang, X., Chen, X., Feng, X., Chang, F., Chen, M., Xia, Y., and Chen, L. (2015). Triclosan causes spontaneous abortion accompanied by decline of estrogen sulfotransferase activity in humans and mice. Sci. Rep., 5.","DOI":"10.1038\/srep18252"},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1093\/toxsci\/kfn171","article-title":"Higher levels of ethyl paraben and butyl paraben in rat amniotic fluid than in maternal plasma after subcutaneous administration","volume":"106","author":"Frederiksen","year":"2008","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"128307","DOI":"10.1016\/j.chemosphere.2020.128307","article-title":"Independent and combined effects of Bisphenol A and Diethylhexyl Phthalate on gestational outcomes and offspring development in Sprague-Dawley rats","volume":"263","author":"Dagher","year":"2021","journal-title":"Chemosphere"},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"37010","DOI":"10.1289\/EHP10640","article-title":"Evaluating the Effects of BPA and TBBPA Exposure on Pregnancy Loss and Maternal-Fetal Immune Cells in Mice","volume":"130","author":"Reed","year":"2022","journal-title":"Environ. Health Perspect."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s00204-018-2338-1","article-title":"Exposure of pregnant mice to triclosan causes hyperphagic obesity of offspring via the hypermethylation of proopiomelanocortin promoter","volume":"93","author":"Hua","year":"2019","journal-title":"Arch. Toxicol."},{"key":"ref_161","doi-asserted-by":"crossref","unstructured":"Li, J., Quan, X., Zhang, Y., Yu, T., Lei, S., Huang, Z., Wang, Q., Song, W., Yang, X., and Xu, P. (2021). PPAR\u03b3 Regulates Triclosan Induced Placental Dysfunction. Cells, 11.","DOI":"10.3390\/cells11010086"},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1002\/tox.22812","article-title":"Maternal exposure to triclosan causes fetal development restriction, deregulation of the oestrous cycle, and alters uterine tissue in rat offspring","volume":"34","author":"Bitencourt","year":"2019","journal-title":"Environ. Toxicol."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.reprotox.2016.12.003","article-title":"Maternal di-(2-ethylhexyl) phthalate exposure during pregnancy causes fetal growth restriction in a stage-specific but gender-independent manner","volume":"67","author":"Shen","year":"2017","journal-title":"Reprod. Toxicol."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jhazmat.2015.04.065","article-title":"Maternal exposure to di-(2-ethylhexyl) phthalate disrupts placental growth and development in pregnant mice","volume":"297","author":"Zong","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1177\/0960327120954259","article-title":"Gene expression in rat placenta after exposure to di(2-ethylhexyl) phthalate","volume":"40","author":"Xu","year":"2021","journal-title":"Hum. Exp. Toxicol."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.placenta.2008.08.011","article-title":"Maternal di-(2-ethylhexyl)-phthalate exposure influences essential fatty acid homeostasis in rat placenta","volume":"29","author":"Xu","year":"2008","journal-title":"Placenta"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1177\/0748233717711868","article-title":"Comparative developmental toxicity evaluation of di- n-hexyl phthalate and dicyclohexyl phthalate in rats","volume":"33","author":"Ahbab","year":"2017","journal-title":"Toxicol. Ind. Health"},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1002\/bdrb.20016","article-title":"Developmental toxicity evaluation of butylparaben in Sprague-Dawley rats","volume":"71","author":"Daston","year":"2004","journal-title":"Birth Defects Res. Part B Dev. Reprod. Toxicol."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.reprotox.2009.03.003","article-title":"Estrogenicity of parabens revisited: Impact of parabens on early pregnancy and an uterotrophic assay in mice","volume":"28","author":"Shaw","year":"2009","journal-title":"Reprod. Toxicol."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.tox.2008.05.020","article-title":"Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats","volume":"250","author":"Boberg","year":"2008","journal-title":"Toxicology"},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1002\/jat.4208","article-title":"Exposure to ethylparaben and propylparaben interfere with embryo implantation by compromising endometrial decidualization in early pregnant mice","volume":"41","author":"Wang","year":"2021","journal-title":"J. Appl. Toxicol. JAT"},{"key":"ref_172","doi-asserted-by":"crossref","unstructured":"Berger, K., Hyland, C., Ames, J.L., Mora, A.M., Huen, K., Eskenazi, B., Holland, N., and Harley, K.G. (2021). Prenatal Exposure to Mixtures of Phthalates, Parabens, and Other Phenols and Obesity in Five-Year-Olds in the CHAMACOS Cohort. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18041796"},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"67009","DOI":"10.1289\/EHP5975","article-title":"Early-Life Environmental Exposures and Childhood Obesity: An Exposome-Wide Approach","volume":"128","author":"Vrijheid","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"107527","DOI":"10.1016\/j.envint.2022.107527","article-title":"Prenatal exposure to mixtures of phthalates and phenols and body mass index and blood pressure in Spanish preadolescents","volume":"169","author":"Montazeri","year":"2022","journal-title":"Environ. Int."},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"57002","DOI":"10.1289\/EHP13644","article-title":"Fetal and Infancy Exposure to Phenols, Parabens, and Phthalates and Anthropometric Measurements up to 36 Months, in the Longitudinal SEPAGES Cohort","volume":"132","author":"Ouidir","year":"2024","journal-title":"Environ. Health Perspect."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"115008","DOI":"10.1016\/j.envpol.2020.115008","article-title":"Maternal prenatal urinary bisphenol A level and child cardio-metabolic risk factors: A prospective cohort study","volume":"265","author":"Ouyang","year":"2020","journal-title":"Environ. Pollut."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.envres.2017.03.038","article-title":"Bisphenol A and phthalates in utero and in childhood: Association with child BMI z-score and adiposity","volume":"156","author":"Yang","year":"2017","journal-title":"Environ. Res."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/EDE.0000000000000132","article-title":"Prenatal exposure to phenols and growth in boys","volume":"25","author":"Philippat","year":"2014","journal-title":"Epidemiology"},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.envres.2016.01.017","article-title":"Association of early life exposure to bisphenol A with obesity and cardiometabolic traits in childhood","volume":"146","author":"Vafeiadi","year":"2016","journal-title":"Environ. Res."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1289\/ehp.1205548","article-title":"Prenatal and postnatal bisphenol A exposure and body mass index in childhood in the CHAMACOS cohort","volume":"121","author":"Harley","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.envres.2019.02.038","article-title":"Association between gestational urinary bisphenol a concentrations and adiposity in young children: The MIREC study","volume":"172","author":"Braun","year":"2019","journal-title":"Environ. Res."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"126340","DOI":"10.1016\/j.chemosphere.2020.126340","article-title":"Urinary bisphenol A concentrations and adiposity measures at age 7 years in a prospective birth cohort","volume":"251","author":"Guo","year":"2020","journal-title":"Chemosphere"},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1016\/j.scitotenv.2017.08.317","article-title":"Prenatal Bisphenol-A exposure affects fetal length growth by maternal glutathione transferase polymorphisms, and neonatal exposure affects child volume growth by sex: From multiregional prospective birth cohort MOCEH study","volume":"612","author":"Lee","year":"2018","journal-title":"Sci. Total Environ."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.envint.2018.07.022","article-title":"The association of repeated measurements of prenatal exposure to triclosan with fetal and early-childhood growth","volume":"120","author":"Wu","year":"2018","journal-title":"Environ. Int."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"e2633","DOI":"10.1210\/clinem\/dgab167","article-title":"Prenatal Exposure to Butyl Paraben Is Associated With Fat Percentage in 7-Year-Old Boys","volume":"106","author":"Kyhl","year":"2021","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.envpol.2016.12.040","article-title":"Urinary paraben concentrations and their associations with anthropometric measures of children aged 3 years","volume":"222","author":"Guo","year":"2017","journal-title":"Environ. Pollut."},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/EDE.0000000000000436","article-title":"Prenatal Phthalate Exposures and Body Mass Index Among 4- to 7-Year-old Children: A Pooled Analysis","volume":"27","author":"Buckley","year":"2016","journal-title":"Epidemiology"},{"key":"ref_188","doi-asserted-by":"crossref","unstructured":"Lee, D.W., Lim, H.M., Lee, J.Y., Min, K.B., Shin, C.H., Lee, Y.A., and Hong, Y.C. (2022). Prenatal exposure to phthalate and decreased body mass index of children: A systematic review and meta-analysis. Sci. Rep., 12.","DOI":"10.1038\/s41598-022-13154-9"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"146146","DOI":"10.1016\/j.scitotenv.2021.146146","article-title":"Trimester-specific and sex-specific effects of prenatal exposure to di(2-ethylhexyl) phthalate on fetal growth, birth size, and early-childhood growth: A longitudinal prospective cohort study","volume":"777","author":"Li","year":"2021","journal-title":"Sci. Total Environ."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"110313","DOI":"10.1016\/j.envres.2020.110313","article-title":"The influence of prenatal exposure to phthalates on subsequent male growth and body composition in adolescence","volume":"195","author":"Berman","year":"2021","journal-title":"Environ. Res."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1289\/ehp.1408887","article-title":"Prenatal Phthalate Exposure and Childhood Growth and Blood Pressure: Evidence from the Spanish INMA-Sabadell Birth Cohort Study","volume":"123","author":"Valvi","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"47006","DOI":"10.1289\/EHP10077","article-title":"Prenatal Phthalate Exposure and Child Weight and Adiposity from in Utero to 6 Years of Age","volume":"130","author":"Ferguson","year":"2022","journal-title":"Environ. Health Perspect."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/pr.2017.112","article-title":"Association of prenatal urinary phthalate metabolite concentrations and childhood BMI and obesity","volume":"82","author":"Harley","year":"2017","journal-title":"Pediatr. Res."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.envres.2016.08.033","article-title":"Phthalate pregnancy exposure and male offspring growth from the intra-uterine period to five years of age","volume":"151","author":"Botton","year":"2016","journal-title":"Environ. Res."},{"key":"ref_195","doi-asserted-by":"crossref","unstructured":"Bowman, A., Peterson, K.E., Dolinoy, D.C., Meeker, J.D., S\u00e1nchez, B.N., Mercado-Garcia, A., T\u00e9llez-Rojo, M.M., and Goodrich, J.M. (2019). Phthalate Exposures, DNA Methylation and Adiposity in Mexican Children Through Adolescence. Front. Public Health, 7.","DOI":"10.3389\/fpubh.2019.00162"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"097008","DOI":"10.1289\/EHP1022","article-title":"Early-Life Phthalate Exposure and Adiposity at 8 Years of Age","volume":"125","author":"Shoaff","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.envres.2019.04.036","article-title":"Heterogeneity in childhood body mass trajectories in relation to prenatal phthalate exposure","volume":"175","author":"Heggeseth","year":"2019","journal-title":"Environ. Res."},{"key":"ref_198","doi-asserted-by":"crossref","unstructured":"Vafeiadi, M., Myridakis, A., Roumeliotaki, T., Margetaki, K., Chalkiadaki, G., Dermitzaki, E., Venihaki, M., Sarri, K., Vassilaki, M., and Leventakou, V. (2018). Association of Early Life Exposure to Phthalates With Obesity and Cardiometabolic Traits in Childhood: Sex Specific Associations. Front. Public Health, 6.","DOI":"10.3389\/fpubh.2018.00327"},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"112111","DOI":"10.1016\/j.envres.2021.112111","article-title":"Prenatal maternal phthalate exposures and trajectories of childhood adiposity from four to twelve years","volume":"204","author":"Kupsco","year":"2022","journal-title":"Environ. Res."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1289\/ehp.1509788","article-title":"Prenatal Phthalate Exposures and Childhood Fat Mass in a New York City Cohort","volume":"124","author":"Buckley","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"113837","DOI":"10.1016\/j.ecoenv.2022.113837","article-title":"Prenatal single and combined exposure to phthalates associated with girls\u2019 BMI trajectory in the first six years","volume":"241","author":"Gao","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"e2412040","DOI":"10.1001\/jamanetworkopen.2024.12040","article-title":"Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children","volume":"7","author":"Stratakis","year":"2024","journal-title":"JAMA Netw. Open"},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12940-018-0366-1","article-title":"Early life Triclosan exposure and child adiposity at 8 Years of age: A prospective cohort study","volume":"17","author":"Kalloo","year":"2018","journal-title":"Environ. Health"},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"109020","DOI":"10.1016\/j.envres.2019.109020","article-title":"Prenatal exposure to di-(2-ethylhexyl) phthalate and decreased skeletal muscle mass in 6-year-old children: A prospective birth cohort study","volume":"182","author":"Lee","year":"2020","journal-title":"Environ. Res."},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1289\/ehp.1408750","article-title":"Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort","volume":"124","author":"Maresca","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"101532","DOI":"10.1016\/j.beem.2021.101532","article-title":"Associations of prenatal exposure to phthalates and one phthalate substitute with anthropometric measures in early life: Results from the German LIFE Child cohort study","volume":"35","author":"Nidens","year":"2021","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"112519","DOI":"10.1016\/j.fct.2021.112519","article-title":"Prenatal exposure to a mixture of different phthalates increases the risk of mammary carcinogenesis in F1 female offspring","volume":"156","author":"Zapaterini","year":"2021","journal-title":"Food Chem. Toxicol."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"87006","DOI":"10.1289\/EHP11798","article-title":"Early-Life Exposure to a Mixture of Phenols and Phthalates in Relation to Child Social Behavior: Applying an Evidence-Based Prioritization to a Cohort with Improved Exposure Assessment","volume":"131","author":"Mustieles","year":"2023","journal-title":"Environ. Health Perspect."},{"key":"ref_209","first-page":"93","article-title":"Perinatal oral exposure to low doses of bisphenol A, S or F impairs immune functions at intestinal and systemic levels in female offspring mice","volume":"19","author":"Lencina","year":"2020","journal-title":"Environ. Health A Glob. Access Sci. Source"},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.envpol.2019.03.100","article-title":"Short and long-term effects of bisphenol S (BPS) exposure during pregnancy and lactation on plasma lipids, hormones, and behavior in rats","volume":"250","author":"Pietrobon","year":"2019","journal-title":"Environ. Pollut."},{"key":"ref_211","doi-asserted-by":"crossref","unstructured":"Taylor, J.A., Sommerfeld-Sager, J.M., Meng, C.X., Nagel, S.C., Shioda, T., and Vom Saal, F.S. (2018). Reduced body weight at weaning followed by increased post-weaning growth rate interacts with part-per-trillion fetal serum concentrations of bisphenol A (BPA) to impair glucose tolerance in male mice. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0208846"},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"111681","DOI":"10.1016\/j.fct.2020.111681","article-title":"Bisphenol-A exposure during pregnancy alters pancreatic \u03b2-cell division and mass in male mice offspring: A role for ER\u03b2","volume":"145","author":"Ferrero","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1017\/S2040174418000764","article-title":"Transgenerational effects of maternal bisphenol: A exposure on offspring metabolic health","volume":"10","author":"Bansal","year":"2019","journal-title":"J. Dev. Orig. Health Dis."},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"111716","DOI":"10.1016\/j.fct.2020.111716","article-title":"Paternal bisphenol A exposure in mice impairs glucose tolerance in female offspring","volume":"145","author":"Rashid","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"143466","DOI":"10.1016\/j.scitotenv.2020.143466","article-title":"Effects on the liver lipidome of rat offspring prenatally exposed to bisphenol A","volume":"759","author":"Nguyen","year":"2021","journal-title":"Sci. Total Environ."},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"137568","DOI":"10.1016\/j.scitotenv.2020.137568","article-title":"Effects of prenatal bisphenol A exposure on the hepatic transcriptome and proteome in rat offspring","volume":"720","author":"Nguyen","year":"2020","journal-title":"Sci. Total Environ."},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"E238","DOI":"10.1152\/ajpendo.00425.2015","article-title":"Developmental programming: Interaction between prenatal BPA exposure and postnatal adiposity on metabolic variables in female sheep","volume":"310","author":"Moeller","year":"2016","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"ref_218","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.reprotox.2019.03.002","article-title":"Developmental programming: Changes in mediators of insulin sensitivity in prenatal bisphenol A-treated female sheep","volume":"85","author":"Puttabyatappa","year":"2019","journal-title":"Reprod. Toxicol."},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"116161","DOI":"10.1016\/j.taap.2022.116161","article-title":"Developmental programming: Impact of prenatal bisphenol-A exposure on liver and muscle transcriptome of female sheep","volume":"451","author":"Puttabyatappa","year":"2022","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_220","doi-asserted-by":"crossref","first-page":"112202","DOI":"10.1016\/j.mce.2024.112202","article-title":"Developmental programming: An exploratory analysis of pancreatic islet compromise in female sheep resulting from gestational BPA exposure","volume":"588","author":"Ciarelli","year":"2024","journal-title":"Mol. Cell. Endocrinol."},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.1210\/en.2016-1390","article-title":"Maternal Exposure to Bisphenol-A During Pregnancy Increases Pancreatic \u03b2-Cell Growth During Early Life in Male Mice Offspring","volume":"157","author":"Servitja","year":"2016","journal-title":"Endocrinology"},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1289\/ehp.1001993","article-title":"Bisphenol A exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring","volume":"118","author":"Vieira","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.fct.2019.02.023","article-title":"In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring","volume":"126","author":"Esteban","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.etap.2016.09.017","article-title":"Gestational and lactational exposure to low-dose bisphenol A increases Th17 cells in mice offspring","volume":"47","author":"Luo","year":"2016","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3109\/1547691X.2013.822036","article-title":"Perinatal bisphenol A exposures increase production of pro-inflammatory mediators in bone marrow-derived mast cells of adult mice","volume":"11","author":"Dolinoy","year":"2014","journal-title":"J. Immunotoxicol."},{"key":"ref_226","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1210\/en.2014-2027","article-title":"Bisphenol a exposure disrupts metabolic health across multiple generations in the mouse","volume":"156","author":"Susiarjo","year":"2015","journal-title":"Endocrinology"},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.tox.2014.04.001","article-title":"Programming of metabolic effects in C57BL\/6JxFVB mice by exposure to bisphenol A during gestation and lactation","volume":"321","author":"Lamoree","year":"2014","journal-title":"Toxicology"},{"key":"ref_228","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1093\/toxsci\/kft242","article-title":"Transmaternal bisphenol A exposure accelerates diabetes type 1 development in NOD mice","volume":"137","author":"Bodin","year":"2014","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1096\/fj.12-223545","article-title":"Perinatal bisphenol A exposure promotes hyperactivity, lean body composition, and hormonal responses across the murine life course","volume":"27","author":"Anderson","year":"2013","journal-title":"FASEB J."},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1507\/endocrj.EJ16-0257","article-title":"Maternal Triclosan consumption alters the appetite regulatory network on Wistar rat offspring and predispose to metabolic syndrome in the adulthood","volume":"63","author":"Rabaglino","year":"2016","journal-title":"Endocr. J."},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"109004","DOI":"10.1016\/j.envres.2019.109004","article-title":"Perinatal Triclosan exposure in the rat induces long-term disturbances in metabolism and gut microbiota in adulthood and old age","volume":"182","author":"Ma","year":"2020","journal-title":"Environ. Res."},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"4346","DOI":"10.1038\/s41467-022-31947-4","article-title":"Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice","volume":"13","author":"Weber","year":"2022","journal-title":"Nat. Commun."},{"key":"ref_233","first-page":"337","article-title":"Potential effect of combined xenoestrogens during gestation stages on mouse offspring","volume":"36","author":"Vo","year":"2015","journal-title":"J. Environ. Biol."},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/s41467-019-14202-1","article-title":"Maternal paraben exposure triggers childhood overweight development","volume":"11","author":"Leppert","year":"2020","journal-title":"Nat. Commun."},{"key":"ref_235","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.chemosphere.2017.08.165","article-title":"Systematic review and meta-analysis of early life exposure to di(2-ethylhexyl) phthalate and obesity related outcomes in rodents","volume":"188","author":"Wassenaar","year":"2017","journal-title":"Chemosphere"},{"key":"ref_236","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s00204-015-1539-0","article-title":"Maternal exposure to di-(2-ethylhexyl) phthalate exposure deregulates blood pressure, adiposity, cholesterol metabolism and social interaction in mouse offspring","volume":"90","author":"Lee","year":"2016","journal-title":"Arch. Toxicol."},{"key":"ref_237","doi-asserted-by":"crossref","first-page":"dvaa017","DOI":"10.1093\/eep\/dvaa017","article-title":"Short- and long-term effects of perinatal phthalate exposures on metabolic pathways in the mouse liver","volume":"6","author":"Neier","year":"2020","journal-title":"Environ. Epigenetics"},{"key":"ref_238","doi-asserted-by":"crossref","first-page":"121534","DOI":"10.1016\/j.jhazmat.2019.121534","article-title":"Prenatal low-dose DEHP exposure induces metabolic adaptation and obesity: Role of hepatic thiamine metabolism","volume":"385","author":"Fan","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/s41390-018-0055-3","article-title":"Perinatal and childhood exposure to environmental chemicals and blood pressure in children: A review of literature 2007\u20132017","volume":"84","author":"Sanders","year":"2018","journal-title":"Pediatr. Res."},{"key":"ref_240","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1177\/09603271211003314","article-title":"Perinatal exposure to di-(2-ethylhexyl) phthalate induces hepatic lipid accumulation mediated by diacylglycerol acyltransferase 1","volume":"40","author":"An","year":"2021","journal-title":"Hum. Exp. Toxicol."},{"key":"ref_241","doi-asserted-by":"crossref","first-page":"103958","DOI":"10.1016\/j.etap.2022.103958","article-title":"Di(2-ethylhexyl) phthalate disturbs cholesterol metabolism through oxidative stress in rat liver","volume":"95","author":"Li","year":"2022","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"ref_242","first-page":"531","article-title":"The Development of Metabolic Derangement in Male Offspring after Perinatal Exposure to Di-(2-Ethylhexyl) Phthalate","volume":"31","author":"Yang","year":"2018","journal-title":"Biomed. Environ. Sci. BES"},{"key":"ref_243","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.tox.2019.03.008","article-title":"Effects of in utero and lactational exposure to phthalates on reproductive development and glycemic homeostasis in rats","volume":"421","author":"Venturelli","year":"2019","journal-title":"Toxicology"},{"key":"ref_244","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.toxlet.2014.09.025","article-title":"Gestational exposure to di(2-ethylhexyl) phthalate (DEHP) impairs pancreatic \u03b2-cell function in F1 rat offspring","volume":"232","author":"Rajesh","year":"2015","journal-title":"Toxicol. Lett."},{"key":"ref_245","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/jat.3764","article-title":"Maternal di-(2-ethylhexyl) phthalate exposure alters hepatic insulin signal transduction and glucoregulatory events in rat F(1) male offspring","volume":"39","author":"Rajagopal","year":"2019","journal-title":"J. Appl. Toxicol. JAT"},{"key":"ref_246","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.etap.2019.01.012","article-title":"Effects of perinatal di (2-ethylhexyl) phthalate exposure on thyroid function in rat offspring","volume":"67","author":"Dong","year":"2019","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"ref_247","doi-asserted-by":"crossref","first-page":"26322","DOI":"10.1007\/s11356-018-2596-8","article-title":"Transcriptomics and metabonomics analyses of maternal DEHP exposure on male offspring","volume":"25","author":"Zhang","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref_248","doi-asserted-by":"crossref","first-page":"24041","DOI":"10.1007\/s11356-018-2395-2","article-title":"Lycopene reduces in utero bisphenol A exposure-induced mortality, benefits hormones, and development of reproductive organs in offspring mice","volume":"25","author":"Ma","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref_249","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1210\/en.2018-00817","article-title":"Prenatal Bisphenol A Exposure in Mice Induces Multitissue Multiomics Disruptions Linking to Cardiometabolic Disorders","volume":"160","author":"Shu","year":"2019","journal-title":"Endocrinology"},{"key":"ref_250","doi-asserted-by":"crossref","first-page":"9603271221129852","DOI":"10.1177\/09603271221129852","article-title":"Gestational bisphenol A exposure impairs hepatic lipid metabolism by altering mTOR\/CRTC2\/SREBP1 in male rat offspring","volume":"41","author":"Yang","year":"2022","journal-title":"Hum. Exp. Toxicol."},{"key":"ref_251","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1017\/S204017441600057X","article-title":"Effects of prenatal bisphenol-A exposure and postnatal overfeeding on cardiovascular function in female sheep","volume":"8","author":"MohanKumar","year":"2017","journal-title":"J. Dev. Orig. Health Dis."},{"key":"ref_252","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.tox.2013.04.010","article-title":"Exposure to DEHP decreased four fatty acid levels in plasma of prepartum mice","volume":"309","author":"Nakashima","year":"2013","journal-title":"Toxicology"},{"key":"ref_253","doi-asserted-by":"crossref","first-page":"2516865720939971","DOI":"10.1177\/2516865720939971","article-title":"Sex-Specific Programming of Cardiac DNA Methylation by Developmental Phthalate Exposure","volume":"13","author":"Svoboda","year":"2020","journal-title":"Epigenetics Insights"},{"key":"ref_254","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.1002\/jcsm.13098","article-title":"Maternal rodent exposure to di-(2-ethylhexyl) phthalate decreases muscle mass in the offspring by increasing myostatin","volume":"13","author":"Li","year":"2022","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_255","first-page":"920","article-title":"Long-term Di-(2-ethylhexyl) phthalate Exposure Disturbs the Lipid Metabolism Profiles and Hepatic Enzymes in Male Rats: A UPLC-MS-based Serum Metabolomics Analysis","volume":"34","author":"Dong","year":"2021","journal-title":"Biomed. Environ. Sci. BES"},{"key":"ref_256","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.taap.2012.10.027","article-title":"Maternal in utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate affects the blood pressure of adult male offspring","volume":"266","author":"McIntosh","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_257","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1095\/biolreprod.110.089920","article-title":"In utero exposure to the antiandrogen di-(2-ethylhexyl) phthalate decreases adrenal aldosterone production in the adult rat","volume":"85","author":"Guichard","year":"2011","journal-title":"Biol. Reprod."},{"key":"ref_258","doi-asserted-by":"crossref","first-page":"5802","DOI":"10.1002\/jcb.27866","article-title":"Postnatal exposure to di-(2-ethylhexyl)phthalate alters cardiac insulin signaling molecules and GLUT4(Ser488) phosphorylation in male rat offspring","volume":"120","author":"Parsanathan","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"ref_259","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1210\/en.2013-1921","article-title":"In utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate induces long-term changes in gene expression in the adult male adrenal gland","volume":"155","author":"Campioli","year":"2014","journal-title":"Endocrinology"},{"key":"ref_260","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.toxlet.2012.05.023","article-title":"Maternal exposure to di-(2-ethylhexyl)phthalate alters kidney development through the renin-angiotensin system in offspring","volume":"212","author":"Wei","year":"2012","journal-title":"Toxicol. Lett."},{"key":"ref_261","doi-asserted-by":"crossref","first-page":"31101","DOI":"10.18632\/oncotarget.16088","article-title":"Maternal exposure to di-n-butyl phthalate (DBP) induces renal fibrosis in adult rat offspring","volume":"8","author":"Zhu","year":"2017","journal-title":"Oncotarget"},{"key":"ref_262","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.toxlet.2017.09.009","article-title":"Potential involvement of Fgf10\/Fgfr2 and androgen receptor (AR) in renal fibrosis in adult male rat offspring subjected to prenatal exposure to di-n-butyl phthalate (DBP)","volume":"282","author":"Sun","year":"2018","journal-title":"Toxicol. Lett."},{"key":"ref_263","doi-asserted-by":"crossref","first-page":"152573","DOI":"10.1016\/j.tox.2020.152573","article-title":"Activation of the RhoA\/ROCK pathway contributes to renal fibrosis in offspring rats induced by maternal exposure to di-n-butyl phthalate","volume":"443","author":"Ye","year":"2020","journal-title":"Toxicology"},{"key":"ref_264","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1093\/toxsci\/kfw079","article-title":"Multiple Endocrine Disrupting Effects in Rats Perinatally Exposed to Butylparaben","volume":"152","author":"Boberg","year":"2016","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_265","doi-asserted-by":"crossref","unstructured":"Zhao, S., Pan, L., Chen, M., Zhu, Y.P., Han, B.M., Xia, S.J., and Jiang, J.T. (2020). In utero di-n-butyl phthalate exposure induced abnormal autophagy in renal tubular cells via hedgehog signaling in newborn rats. Chem. Biol. Interact., 328.","DOI":"10.1016\/j.cbi.2020.109189"},{"key":"ref_266","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.envres.2017.01.033","article-title":"Exposure to phthalates is associated with lipid profile in peripubertal Mexican youth","volume":"154","author":"Perng","year":"2017","journal-title":"Environ. Res."},{"key":"ref_267","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/j.jacc.2019.06.069","article-title":"Early-Life Environmental Exposures and Blood Pressure in Children","volume":"74","author":"Warembourg","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_268","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.reprotox.2016.08.015","article-title":"Effects of early exposure to phthalates and bisphenols on cardiometabolic outcomes in pregnancy and childhood","volume":"68","author":"Philips","year":"2017","journal-title":"Reprod. Toxicol."},{"key":"ref_269","doi-asserted-by":"crossref","unstructured":"Tain, Y.L., Hou, C.Y., Chang-Chien, G.P., Lin, S., and Hsu, C.N. (2023). Resveratrol Butyrate Ester Supplementation Blunts the Development of Offspring Hypertension in a Maternal Di-2-ethylhexyl Phthalate Exposure Rat Model. Nutrients, 15.","DOI":"10.3390\/nu15030697"},{"key":"ref_270","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.ecoenv.2018.10.073","article-title":"Maternal exposure to di-n-butyl phthalate promotes Snail1-mediated epithelial-mesenchymal transition of renal tubular epithelial cells via upregulation of TGF-\u03b21 during renal fibrosis in rat offspring","volume":"169","author":"Zhao","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_271","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s12012-015-9337-8","article-title":"Prenatal Exposure to Phthalic Acid Induces Increased Blood Pressure, Oxidative Stress, and Markers of Endothelial Dysfunction in Rat Offspring","volume":"16","author":"Rahmani","year":"2016","journal-title":"Cardiovasc. Toxicol."},{"key":"ref_272","doi-asserted-by":"crossref","unstructured":"Hart, R.J. (2020). The Impact of Prenatal Exposure to Bisphenol A on Male Reproductive Function. Front. Endocrinol., 11.","DOI":"10.3389\/fendo.2020.00320"},{"key":"ref_273","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1210\/jc.2012-4057","article-title":"Clinical review: Anogenital distance or digit length ratio as measures of fetal androgen exposure: Relationship to male reproductive development and its disorders","volume":"98","author":"Dean","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_274","doi-asserted-by":"crossref","first-page":"25","DOI":"10.4274\/jcrpe.4817","article-title":"High Prenatal Exposure to Bisphenol A Reduces Anogenital Distance in Healthy Male Newborns","volume":"10","author":"Mammadov","year":"2018","journal-title":"J. Clin. Res. Pediatr. Endocrinol."},{"key":"ref_275","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.envint.2018.08.055","article-title":"Maternal exposure to bisphenol A and anogenital distance throughout infancy: A longitudinal study from Shanghai, China","volume":"121","author":"Sun","year":"2018","journal-title":"Environ. Int."},{"key":"ref_276","doi-asserted-by":"crossref","first-page":"97004","DOI":"10.1289\/EHP3424","article-title":"Association of Prenatal Urinary Concentrations of Phthalates and Bisphenol A and Pubertal Timing in Boys and Girls","volume":"126","author":"Berger","year":"2018","journal-title":"Environ. Health Perspect."},{"key":"ref_277","doi-asserted-by":"crossref","first-page":"114418","DOI":"10.1016\/j.ijheh.2024.114418","article-title":"Association of prenatal exposure to phthalates and synthetic phenols with pubertal development in three European cohorts","volume":"261","author":"Freire","year":"2024","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"ref_278","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.reprotox.2014.06.002","article-title":"Prenatal and peripubertal phthalates and bisphenol A in relation to sex hormones and puberty in boys","volume":"47","author":"Ferguson","year":"2014","journal-title":"Reprod. Toxicol."},{"key":"ref_279","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.rbmo.2017.11.009","article-title":"The impact of antenatal Bisphenol A exposure on male reproductive function at 20\u201322 years of age","volume":"36","author":"Hart","year":"2018","journal-title":"Reprod. Biomed. Online"},{"key":"ref_280","doi-asserted-by":"crossref","unstructured":"Holmboe, S.A., Scheutz Henriksen, L., Frederiksen, H., Andersson, A.M., Priskorn, L., J\u00f8rgensen, N., Juul, A., Toppari, J., Skakkeb\u00e6k, N.E., and Main, K.M. (2022). Prenatal exposure to phenols and benzophenones in relation to markers of male reproductive function in adulthood. Front. Endocrinol., 13.","DOI":"10.3389\/fendo.2022.1071761"},{"key":"ref_281","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.envint.2017.11.007","article-title":"Impacts of prenatal triclosan exposure on fetal reproductive hormones and its potential mechanism","volume":"111","author":"Wang","year":"2018","journal-title":"Environ. Int."},{"key":"ref_282","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/humrep\/dey337","article-title":"Association of phthalates, parabens and phenols found in personal care products with pubertal timing in girls and boys","volume":"34","author":"Harley","year":"2019","journal-title":"Hum. Reprod."},{"key":"ref_283","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1289\/ehp.8100","article-title":"Decrease in anogenital distance among male infants with prenatal phthalate exposure","volume":"113","author":"Swan","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"ref_284","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.envres.2016.07.043","article-title":"First trimester phthalate exposure and male newborn genital anomalies","volume":"151","author":"Sathyanarayana","year":"2016","journal-title":"Environ. Res."},{"key":"ref_285","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.reprotox.2020.04.078","article-title":"Prenatal exposure to phthalates and male reproductive system development: Results from a Canadian pregnancy cohort study","volume":"95","author":"Romao","year":"2020","journal-title":"Reprod. Toxicol."},{"key":"ref_286","doi-asserted-by":"crossref","first-page":"113606","DOI":"10.1016\/j.envres.2022.113606","article-title":"Association of prenatal phthalate exposure with pubertal development in Spanish boys and girls","volume":"213","author":"Freire","year":"2022","journal-title":"Environ. Res."},{"key":"ref_287","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.envres.2017.07.051","article-title":"Phthalate and bisphenol A exposure during in utero windows of susceptibility in relation to reproductive hormones and pubertal development in girls","volume":"159","author":"Watkins","year":"2017","journal-title":"Environ. Res."},{"key":"ref_288","doi-asserted-by":"crossref","first-page":"161914","DOI":"10.1016\/j.scitotenv.2023.161914","article-title":"Maternal phthalate exposure during pregnancy and testis function of young adult sons","volume":"871","author":"Henriksen","year":"2023","journal-title":"Sci. Total Environ."},{"key":"ref_289","doi-asserted-by":"crossref","first-page":"28940","DOI":"10.1007\/s11356-019-06153-3","article-title":"Maternal exposure to environmentally relevant doses of bisphenol A causes reproductive dysfunction in F1 adult male rats: Protective role of melatonin","volume":"26","author":"Olukole","year":"2019","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref_290","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.lfs.2018.12.039","article-title":"Effects of maternal bisphenol A on behavior, sex steroid and thyroid hormones levels in the adult rat offspring","volume":"218","author":"Silva","year":"2019","journal-title":"Life Sci."},{"key":"ref_291","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1080\/15287394.2019.1572557","article-title":"Maternal bisphenol A exposure disrupts spermatogenesis in adult rat offspring","volume":"82","author":"Campos","year":"2019","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"ref_292","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.lfs.2009.10.004","article-title":"Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring","volume":"85","author":"Salian","year":"2009","journal-title":"Life Sci."},{"key":"ref_293","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.taap.2018.03.021","article-title":"Effects of continuous bisphenol A exposure from early gestation on 90 day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study","volume":"347","author":"Dere","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_294","doi-asserted-by":"crossref","first-page":"23491","DOI":"10.1007\/s11356-019-05579-z","article-title":"Maternal exposure to bisphenol A during pregnancy interferes testis development of F1 male mice","volume":"26","author":"Wei","year":"2019","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref_295","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.chemosphere.2019.05.044","article-title":"Hazards of bisphenol A\u2014blocks RNA splicing leading to abnormal testicular development in offspring male mice","volume":"230","author":"Zhang","year":"2019","journal-title":"Chemosphere"},{"key":"ref_296","doi-asserted-by":"crossref","unstructured":"Ma, S., Shi, W., Wang, X., Song, P., and Zhong, X. (2017). Bisphenol A Exposure during Pregnancy Alters the Mortality and Levels of Reproductive Hormones and Genes in Offspring Mice. BioMed. Res. Int., 2017.","DOI":"10.1155\/2017\/3585809"},{"key":"ref_297","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1387\/ijdb.200185hm","article-title":"Bisphenol A alters differentiation of Leydig cells in the rabbit fetal testis","volume":"65","year":"2021","journal-title":"Int. J. Dev. Biol."},{"key":"ref_298","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/toxsci\/kfg036","article-title":"Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure","volume":"72","author":"Higuchi","year":"2003","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_299","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.reprotox.2020.06.014","article-title":"Gestational and pubertal exposure to low dose of di-(2-ethylhexyl) phthalate impairs sperm quality in adult mice","volume":"96","author":"Dostalova","year":"2020","journal-title":"Reprod. Toxicol."},{"key":"ref_300","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.toxlet.2007.03.004","article-title":"Differential expression of the phthalate syndrome in male Sprague-Dawley and Wistar rats after in utero DEHP exposure","volume":"170","author":"Wilson","year":"2007","journal-title":"Toxicol. Lett."},{"key":"ref_301","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/toxsci\/kfr146","article-title":"Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following in utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate","volume":"123","author":"Hannas","year":"2011","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_302","doi-asserted-by":"crossref","unstructured":"Repouskou, A., Panagiotidou, E., Panagopoulou, L., Bisting, P.L., Tuck, A.R., Sj\u00f6din, M.O.D., Lindberg, J., Bozas, E., R\u00fcegg, J., and Gennings, C. (2019). Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes. Sci. Rep., 9.","DOI":"10.1038\/s41598-019-42377-6"},{"key":"ref_303","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/toxsci\/kfm069","article-title":"Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: Altered fetal steroid hormones and genes","volume":"99","author":"Howdeshell","year":"2007","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"ref_304","doi-asserted-by":"crossref","first-page":"139","DOI":"10.4067\/S0716-97602013000200004","article-title":"Disruption of reproductive development in male rat offspring following gestational and lactational exposure to di-(2-ethylhexyl) phthalate and genistein","volume":"46","author":"Zhang","year":"2013","journal-title":"Biol. Res."},{"key":"ref_305","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.reprotox.2016.07.004","article-title":"Maternal exposure to a mixture of di(2-ethylhexyl) phthalate (DEHP) and polychlorinated biphenyls (PCBs) causes reproductive dysfunction in adult male mouse offspring","volume":"65","author":"Fiandanese","year":"2016","journal-title":"Reprod. Toxicol."},{"key":"ref_306","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.reprotox.2019.07.017","article-title":"Prenatal exposures to bisphenol A and di (2-ethylhexyl) phthalate disrupted seminiferous tubular development in growing male rats","volume":"88","author":"Ali","year":"2019","journal-title":"Reprod. Toxicol."},{"key":"ref_307","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.theriogenology.2019.09.045","article-title":"Maternal exposure to bisphenol A during pregnancy interferes ovaries development of F1 female mice","volume":"142","author":"Wei","year":"2020","journal-title":"Theriogenology"},{"key":"ref_308","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.reprotox.2020.07.001","article-title":"Adverse reproductive function induced by maternal BPA exposure is associated with abnormal autophagy and activating inflamation via mTOR and TLR4\/NF-\u03baB signaling pathways in female offspring rats","volume":"96","author":"Meng","year":"2020","journal-title":"Reprod. Toxicol."},{"key":"ref_309","doi-asserted-by":"crossref","unstructured":"Hannon, P.R., and Flaws, J.A. (2015). The effects of phthalates on the ovary. Front. Endocrinol., 6.","DOI":"10.3389\/fendo.2015.00008"},{"key":"ref_310","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s11033-013-2967-7","article-title":"Exposure to diethylhexyl phthalate (DEHP) results in a heritable modification of imprint genes DNA methylation in mouse oocytes","volume":"41","author":"Li","year":"2014","journal-title":"Mol. Biol. Rep."},{"key":"ref_311","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1210\/en.2011-1450","article-title":"Exposure to di(2-ethyl-hexyl) phthalate (DEHP) in utero and during lactation causes long-term pituitary-gonadal axis disruption in male and female mouse offspring","volume":"153","author":"Pocar","year":"2012","journal-title":"Endocrinology"},{"key":"ref_312","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1097\/EDE.0000000000000460","article-title":"Within-subject Pooling of Biological Samples to Reduce Exposure Misclassification in Biomarker-based Studies","volume":"27","author":"Perrier","year":"2016","journal-title":"Epidemiology"},{"key":"ref_313","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1093\/humupd\/dmg043","article-title":"A comparison of placental development and endocrine functions between the human and mouse model","volume":"9","author":"Malassine","year":"2003","journal-title":"Hum. Reprod. 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