{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:16:05Z","timestamp":1792174565560,"version":"4.4.0"},"reference-count":129,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Qingdao University of Technology","award":["JC2022-003"],"award-info":[{"award-number":["JC2022-003"]}]},{"award":["JC2022-003"],"award-info":[{"award-number":["JC2022-003"]}],"id":[{"id":"https:\/\/ror.org\/01qzc0f54","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxics"],"abstract":"<jats:p>The widespread occurrence of antibiotics in the environment threatens public health and ecosystem safety. This review summarizes the global occurrence of antibiotic contamination across the different environmental media, i.e., water systems, solid wastes, and soils, and provides a comprehensive analysis of physical, chemical, and biological removal methods, including their mechanisms, application advantages and disadvantages. It is deduced that physical methods aid in antibiotic enrichment, which leads to residual accumulation and fails to achieve complete degradation. In comparison, chemical methods are more efficient and rapid, but they are largely limited by high costs and secondary pollution. Biological methods, despite being appealing due to their low costs and environmental friendliness, may generate and spread antibiotic-resistant bacteria. To overcome the disadvantages of these conventional treatment methods, this review emphasizes the significant potential of integrated antibiotic removal systems, such as coupled advanced oxidation processes (AOPs), physical methods combined with AOPs and chemical methods combined with biological methods, which could achieve superior treatment performance. Future research should focus on optimizing and simplifying coupled systems and developing innovative treatment methods to enhance removal efficiency, reduce operational costs, and minimize secondary toxicity, thereby enabling effective antibiotic pollution remediation. This review summarizes the global state of antibiotic residues and stresses the importance of combined treatment methods for enhancing antibiotic degradation and removal, providing the valuable insights for green and efficient antibiotic treatment.<\/jats:p>","DOI":"10.3390\/toxics14070637","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:17:52Z","timestamp":1784647072000},"page":"637","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Antibiotics in the Environment: Occurrence, Enhanced Removal Strategies and Future Prospects"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4371-253X","authenticated-orcid":false,"given":"Yinglu","family":"Tao","sequence":"first","affiliation":[{"name":"School of Environmental & Municipal Engineering, Qingdao University of Technology, Qingdao 266520, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjun","family":"Xie","sequence":"additional","affiliation":[{"name":"School of Environmental & Municipal Engineering, Qingdao University of Technology, Qingdao 266520, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Environmental & Municipal Engineering, Qingdao University of Technology, Qingdao 266520, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cailing","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Environmental & Municipal Engineering, Qingdao University of Technology, Qingdao 266520, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangrui","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Environmental & Municipal Engineering, Qingdao University of Technology, Qingdao 266520, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaoqi","family":"Li","sequence":"additional","affiliation":[{"name":"School of Environmental & Municipal Engineering, Qingdao University of Technology, Qingdao 266520, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chufei","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Environmental & Municipal Engineering, Qingdao University of Technology, Qingdao 266520, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"103751","DOI":"10.1016\/j.eti.2024.103751","article-title":"Recent advancement of eliminating antibiotic resistance bacteria and antibiotic resistance genes in livestock waste: A review","volume":"36","author":"Pham","year":"2024","journal-title":"Environ. 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