{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T04:48:28Z","timestamp":1785905308354,"version":"3.56.0"},"reference-count":71,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T00:00:00Z","timestamp":1785715200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22176071"],"award-info":[{"award-number":["22176071"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"award":["22176071"],"award-info":[{"award-number":["22176071"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004605","name":"Zhengzhou University","doi-asserted-by":"crossref","award":["332-22120002"],"award-info":[{"award-number":["332-22120002"]}],"id":[{"id":"10.13039\/501100004605","id-type":"DOI","asserted-by":"crossref"}]},{"award":["332-22120002"],"award-info":[{"award-number":["332-22120002"]}],"id":[{"id":"https:\/\/ror.org\/04ypx8c21","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxics"],"abstract":"<jats:p>The global surge in industrial waste generation has raised substantial concerns regarding occupational exposure to per- and polyfluoroalkyl substances (PFASs) and the associated adverse health effects. However, critical knowledge gaps remain regarding the relationships among size-resolved airborne particulate matter (PM)-bound PFASs, internal exposure, and early-stage health damage. We conducted a panel study at a waste recycling plant in southern China, collecting 15 size-resolved PM samples and 280 repeated first morning void urine samples from 20 workers over 45 consecutive days. Relationship between size-resolved PM-bound PFASs, internal exposure, and oxidative stress biomarkers (OSBs:8-hydroxy-2\u2032-deoxyguanosine (8-OHdG), malondialdehyde (MDA)) were analyzed using linear mixed-effects models. Our results indicate that short-chain PFASs predominated in both matrices. Intraclass correlation coefficients (ICCs) for urinary short-chain PFASs ranged from fair to excellent (ICC &gt; 0.4). Notably, inhalation of PFASs in PM2.1\u201310 correlate more strongly with internal exposure than those in PM2.1. For the first time, we observed suggestive quantitative associations between OSBs and multiple short-chain PFASs in urine. More importantly, 8-OHdG levels were mainly correlated with PFASs in PM4.7\u20135.8 and PM9.0\u201310, with each unit increase in ln-transformed average daily intake (ADI) associated with a 10.2\u201312.6% increase in urinary 8-OHdG levels (p &lt; 0.05). Similarly, MDA levels were primarily associated with PFASs bound to PM5.8\u20139.0, with each unit increase in ln-transformed ADI corresponding to an 8.0\u201314.6% increase in MDA (p &lt; 0.05). These findings are exploratory and warrant further confirmation in independent cohorts. Nevertheless, this study highlights the need for more exposure monitoring and health impact assessments regarding PM2.1\u201310-bound short-chain PFASs among the occupational population.<\/jats:p>","DOI":"10.3390\/toxics14080682","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T12:57:56Z","timestamp":1785761876000},"page":"682","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Size-Resolved PM10-Bound PFASs: Respiratory Deposition and Association with Oxidative Stress Biomarkers Among Industrial Waste Recycling Workers"],"prefix":"10.3390","volume":"14","author":[{"given":"Xing","family":"Li","sequence":"first","affiliation":[{"name":"School of Public Health, Zhengzhou University, Zhengzhou 450001, China"},{"name":"Guangdong Key Laboratory of Environmental Pollution and Health, College of Environment and Climate, Jinan University, Guangzhou 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zheng","sequence":"additional","affiliation":[{"name":"Beijing SDL Technology Co., Ltd., Beijing 102206, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"eabg9065","DOI":"10.1126\/science.abg9065","article-title":"Per-and polyfluoroalkyl substances in the environment","volume":"375","author":"Evich","year":"2022","journal-title":"Science"},{"key":"ref_2","first-page":"1","article-title":"POPE: A global gridded emission inventory for PFAS 1950\u20132020","volume":"2024","author":"Simon","year":"2024","journal-title":"Earth Syst. 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