{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:11:37Z","timestamp":1760238697272,"version":"build-2065373602"},"reference-count":53,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2020,8,22]],"date-time":"2020-08-22T00:00:00Z","timestamp":1598054400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union Interreg V\u00d6KS","award":["-"],"award-info":[{"award-number":["-"]}]},{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005275","name":"Region Hovedstaden","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100005275","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Medical Doctor Sofus Carl Emil Friis and Spouse Olga Doris Friis Grant","award":["-"],"award-info":[{"award-number":["-"]}]},{"DOI":"10.13039\/100010727","name":"Axel Muusfeldts Fond","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/100010727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005747","name":"A.P. M\u00f8ller Foundation","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100005747","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxics"],"abstract":"<jats:p>Personal care products (PCPs) may contain multiple chemicals capable of harming male reproductive function. The aim of this study was, therefore, to assess aggregated PCP exposure and potential associations with measures of semen quality in young men. Participants (n = 1058, age 18\u201321) were sampled among young men from the Danish National Birth Cohort (DNBC). Upon recruitment in 2017\u20132019, each man answered an online questionnaire and provided a semen sample. Exposure to 12 common types of PCPs was derived from the questionnaire, and the extent of use and co-use was analyzed. We applied a negative binomial regression model to estimate percentage differences in semen parameters between low, medium and high PCP exposure groups. All participants were exposed to at least one PCP more than once a week, resulting in a mean number (SD) of 5.3 (2.0) PCPs currently used. Most participants (92%) were also exposed to fragranced products on a weekly basis. Little association was observed between aggregated exposure to PCPs and sperm concentration, total sperm count, semen volume, sperm motility and morphology. Despite prevalent use of multiple PCPs, we found little indication of adverse effects of aggregated overall or fragranced PCP exposure on semen quality.<\/jats:p>","DOI":"10.3390\/toxics8030062","type":"journal-article","created":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T22:10:14Z","timestamp":1598220614000},"page":"62","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Use of Personal Care Products and Semen Quality: A Cross-Sectional Study in Young Danish Men"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7370-6800","authenticated-orcid":false,"given":"Kajsa","family":"Ugelvig Petersen","sequence":"first","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2328-9217","authenticated-orcid":false,"given":"Ahmad Mahmoud","family":"Balkiss","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katia Keglberg","family":"H\u00e6rvig","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens Peter","family":"Ellekilde Bonde","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark"},{"name":"Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, \u00d8ster Farimagsgade 5, 1014 Copenhagen K, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin S\u00f8rig","family":"Hougaard","sequence":"additional","affiliation":[{"name":"Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, \u00d8ster Farimagsgade 5, 1014 Copenhagen K, Denmark"},{"name":"National Research Centre for the Working Environment, Lers\u00f8 Parkall\u00e9 105, 2100 Copenhagen \u00d8, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar","family":"Toft","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes All\u00e9 43-45, 8200 Aarhus N, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3296-0121","authenticated-orcid":false,"given":"Cecilia H\u00f8st","family":"Ramlau-Hansen","sequence":"additional","affiliation":[{"name":"Department of Public Health, Research Unit for Epidemiology, Aarhus University, Bartholins All\u00e9 2, 8000 Aarhus C, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra S\u00f8gaard","family":"T\u00f8ttenborg","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,8,22]]},"reference":[{"key":"ref_1","first-page":"192","article-title":"An overview of the causes and consequences of male fertility decline","volume":"3","author":"Jacobs","year":"2019","journal-title":"Percept. 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