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This study aimed to solve the contamination of dried red chili caused by A. flavus by inhibiting the growth of A. flavus and detoxifying aflatoxin B1 (AFB1). In this study, Bacillus subtilis E11 (B. subtilis) screened from 63 candidate antagonistic bacteria exhibited the strongest antifungal ability, which could not only inhibit 64.27% of A. flavus but could also remove 81.34% of AFB1 at 24 h. Notably, scanning electron microscopy (SEM) showed that B. subtilis E11 cells could resist a higher concentration of AFB1, and the fermentation supernatant of B. subtilis E11 could deform the mycelia of A. flavus. After 10 days of coculture with B. subtilis E11 on dried red chili inoculated with A. flavus, the mycelia of A. flavus were almost completely inhibited, and the yield of AFB1 was significantly reduced. Our study first concentrated on the use of B. subtilis as a biocontrol agent for dried red chili, which could not only enrich the resources of microbial strains for controlling A. flavus but also could provide theoretical guidance to prolong the shelf life of dried red chili.<\/jats:p>","DOI":"10.3390\/toxins15050308","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T02:18:34Z","timestamp":1682561914000},"page":"308","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Biocontrol Capabilities of Bacillus subtilis E11 against Aspergillus flavus In Vitro and for Dried Red Chili (Capsicum annuum L.)"],"prefix":"10.3390","volume":"15","author":[{"given":"Shenglan","family":"Yuan","sequence":"first","affiliation":[{"name":"Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Life Sciences\/Institute of Agro-Bioengineering, Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjun","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Life Sciences\/Institute of Agro-Bioengineering, Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2299-788X","authenticated-orcid":false,"given":"Jing","family":"Jin","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Life Sciences\/Institute of Agro-Bioengineering, Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuoqiu","family":"Tong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Life Sciences\/Institute of Agro-Bioengineering, Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9272-3123","authenticated-orcid":false,"given":"Lincheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Life Sciences\/Institute of Agro-Bioengineering, Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yafei","family":"Cai","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Life Sciences\/Institute of Agro-Bioengineering, Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2972","DOI":"10.1111\/1541-4337.12634","article-title":"Capsicum annuum (hot pepper): An ancient Latin-American crop with outstanding bioactive compounds and nutraceutical potential. A review","volume":"19","author":"Valverde","year":"2020","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Costa, J., Rodriguez, R., Garcia-Cela, E., Medina, A., Magan, N., Lima, N., Battilani, P., and Santos, C. (2019). Overview of Fungi and Mycotoxin Contamination in Capsicum Pepper and in Its Derivatives. Toxins, 11.","DOI":"10.3390\/toxins11010027"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.fct.2018.11.047","article-title":"Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods","volume":"124","author":"Rushing","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1111\/ijfs.15103","article-title":"Prevalence of aflatoxin contamination in red chilli pepper (Capsicum annuum L.) from India","volume":"57","author":"Rajendran","year":"2022","journal-title":"Int. J. Food Sci. Technol."},{"key":"#cr-split#-ref_5.1","unstructured":"European Commission (2006). Commission Regulation"},{"key":"#cr-split#-ref_5.2","unstructured":"(EC) No 1881\/2006 Setting Maximum Levels for Certain Contaminants in Foodstuffs. Off. J. Eur. Union, 364, 5-24."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1080\/19440049.2020.1778182","article-title":"Aflatoxin B-1-degrading activity fromBacillus subtilisBCC 42005 isolated from fermented cereal products","volume":"37","author":"Watanakij","year":"2020","journal-title":"Food Addit. Contam. Part A-Chem. Anal. Control Expo. Risk Assess."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Benkerroum, N. (2020). Aflatoxins: Producing-Molds, Structure, Health Issues and Incidence in Southeast Asian and Sub-Saharan African Countries. Int. J. Environ. Res. Public Health, 17.","DOI":"10.20944\/preprints201911.0350.v3"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Chen, T., Liu, J., Li, Y., and Wei, S. (2022). Burden of Disease Associated with Dietary Exposure to Aflatoxins in China in 2020. Nutrients, 14.","DOI":"10.3390\/nu14051027"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Xuan, Z., Ye, J., Zhang, B., Li, L., Wu, Y., and Wang, S. (2019). An Automated and High-Throughput Immunoaffinity Magnetic Bead-Based Sample Clean-Up Platform for the Determination of Aflatoxins in Grains and Oils Using UPLC-FLD. Toxins, 11.","DOI":"10.3390\/toxins11100583"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijfoodmicro.2014.07.029","article-title":"Buckwheat achenes antioxidant profile modulates Aspergillus flavus growth and aflatoxin production","volume":"189","author":"Chitarrini","year":"2014","journal-title":"Int. J. Food Microbiol."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Marchese, S., Polo, A., Ariano, A., Velotto, S., Costantini, S., and Severino, L. (2018). Aflatoxin B1 and M1: Biological Properties and Their Involvement in Cancer Development. Toxins, 10.","DOI":"10.3390\/toxins10060214"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Limaye, A., Yu, R.-C., Chou, C.-C., Liu, J.-R., and Cheng, K.-C. (2018). Protective and Detoxifying Effects Conferred by Dietary Selenium and Curcumin against AFB1-Mediated Toxicity in Livestock: A Review. Toxins, 10.","DOI":"10.3390\/toxins10010025"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Benkerroum, N. (2020). Chronic and Acute Toxicities of Aflatoxins: Mechanisms of Action. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17020423"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s43014-021-00064-y","article-title":"Aflatoxin contamination in food crops: Causes, detection, and management: A review","volume":"3","author":"Kumar","year":"2021","journal-title":"Food Prod. Process. Nutr."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Tumukunde, E., Xie, R., and Wang, S.H. (2021). Updates on the Functions and Molecular Mechanisms of the Genes Involved in Aspergillus flavus Development and Biosynthesis of Aflatoxins. J. Fungi., 7.","DOI":"10.3390\/jof7080666"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ocsci.2020.11.001","article-title":"A review on biosynthesis and genetic regulation of aflatoxin production by major Aspergillus fungi","volume":"5","author":"Liao","year":"2020","journal-title":"Oil Crop Sci."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Caceres, I., Al Khoury, A., El Khoury, R., Lorber, S., Oswald, I., El Khoury, A., Atoui, A., Puel, O., and Bailly, J.-D. (2020). Aflatoxin Biosynthesis and Genetic Regulation: A Review. Toxins, 12.","DOI":"10.3390\/toxins12030150"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Pandey, M.K., Kumar, R., Pandey, A.K., Soni, P., Gangurde, S.S., Sudini, H.K., Fountain, J.C., Liao, B.S., Desmae, H., and Okori, P. (2019). Mitigating Aflatoxin Contamination in Groundnut through A Combination of Genetic Resistance and Post-Harvest Management Practices. Toxins, 11.","DOI":"10.3390\/toxins11060315"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s10123-019-00084-2","article-title":"Genetic regulation of aflatoxin, ochratoxin A, trichothecene, and fumonisin biosynthesis: A review","volume":"23","author":"Vazquez","year":"2020","journal-title":"Int. Microbiol."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Peles, F., Sipos, P., Kovacs, S., Gyori, Z., Pocsi, I., and Pusztahelyi, T. (2021). Biological Control and Mitigation of Aflatoxin Contamination in Commodities. Toxins, 13.","DOI":"10.3390\/toxins13020104"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Zabiulla, I., Malathi, V., Swamy, H.V.L.N., Naik, J., Pineda, L., and Han, Y. (2021). The Efficacy of a Smectite-Based Mycotoxin Binder in Reducing Aflatoxin B-1 Toxicity on Performance, Health and Histopathology of Broiler Chickens. Toxins, 13.","DOI":"10.3390\/toxins13120856"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1111\/ijfs.15088","article-title":"Aflatoxins: Occurrence in red chilli and control by gamma irradiation","volume":"57","author":"Ayob","year":"2022","journal-title":"Int. J. Food Sci. Technol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.ecoenv.2019.03.089","article-title":"Detection of Aflatoxin adducts as potential markers and the role of curcumin in alleviating AFB1-induced liver damage in chickens","volume":"176","author":"Li","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Shabeer, S., Asad, S., Jamal, A., and Ali, A. (2022). Aflatoxin Contamination, Its Impact and Management Strategies: An Updated Review. Toxins, 14.","DOI":"10.3390\/toxins14050307"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3390\/toxins7020439","article-title":"Metabolomics of the Bio-Degradation Process of Aflatoxin B1 by Actinomycetes at an Initial pH of 6.0","volume":"7","author":"Eshelli","year":"2015","journal-title":"Toxins"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.toxicon.2021.02.005","article-title":"Biodegradation of aflatoxin by bacterial species isolated from poultry farms","volume":"195","author":"Ali","year":"2021","journal-title":"Toxicon"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijfoodmicro.2016.07.028","article-title":"Microbial degradation of aflatoxin B1: Current status and future advances","volume":"237","author":"Verheecke","year":"2016","journal-title":"Int. J. Food Microbiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.rvsc.2020.09.009","article-title":"Biodegradation of aflatoxin B-1 with cell-free extracts of Trametes versicolor and Bacillus subtilis","volume":"133","author":"Suresh","year":"2020","journal-title":"Res. Vet. Sci."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"114178","DOI":"10.1016\/j.envpol.2020.114178","article-title":"Detoxification of aflatoxin B1 by Stenotrophomonas sp. CW117 and characterization the thermophilic degradation process","volume":"261","author":"Cai","year":"2020","journal-title":"Environ. Pollut."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1003039","DOI":"10.3389\/fmicb.2022.1003039","article-title":"Characterization and mechanism of aflatoxin degradation by a novel strain of Trichoderma reesei CGMCC3.5218","volume":"13","author":"Yue","year":"2022","journal-title":"Front. Microbiol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/j.1365-2672.2010.04867.x","article-title":"Preparation, purification and characteristics of an aflatoxin degradation enzyme from Myxococcus fulvus ANSM068","volume":"110","author":"Zhao","year":"2011","journal-title":"J. Appl. Microbiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"e01096-20","DOI":"10.1128\/AEM.01096-20","article-title":"Applications of Bacillus subtilis Spores in Biotechnology and Advanced Materials","volume":"86","author":"Zhang","year":"2020","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Raman, J., Kim, J.-S., Choi, K.R., Eun, H., Yang, D., Ko, Y.-J., and Kim, S.-J. (2022). Application of Lactic Acid Bacteria (LAB) in Sustainable Agriculture: Advantages and Limitations. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23147784"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1094\/PHYTO-02-20-0044-R","article-title":"Biological Control of Collar Rot on Passion Fruits Via Induction of Apoptosis in the Collar Rot Pathogen by Bacillus subtilis","volume":"111","author":"Chen","year":"2021","journal-title":"Phytopathology"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"De Simone, N., Capozzi, V., de Chiara, M.L.V., Amodio, M.L., Brahimi, S., Colelli, G., Drider, D., Spano, G., and Russo, P. (2021). Screening of Lactic Acid Bacteria for the Bio-Control of Botrytis cinerea and the Potential of Lactiplantibacillus plantarum for Eco-Friendly Preservation of Fresh-Cut Kiwifruit. Microorganisms, 9.","DOI":"10.3390\/microorganisms9040773"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Ren, X., Zhang, Q., Zhang, W., Mao, J., and Li, P. (2020). Control of Aflatoxigenic Molds by Antagonistic Microorganisms: Inhibitory Behaviors, Bioactive Compounds, Related Mechanisms, and Influencing Factors. Toxins, 12.","DOI":"10.3390\/toxins12010024"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Zhao, Y., Zhang, C., Folly, Y.M.E., Chang, J., Wang, Y., Zhou, L., Zhang, H., and Liu, Y. (2019). Morphological and Transcriptomic Analysis of the Inhibitory Effects of Lactobacillus plantarum on Aspergillus flavus Growth and Aflatoxin Production. Toxins, 11.","DOI":"10.3390\/toxins11110636"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ijfoodmicro.2017.10.025","article-title":"Anti-aflatoxigenic effect of organic acids produced by &ITL actobacillus plantarum &IT","volume":"264","author":"Guimaraes","year":"2018","journal-title":"Int. J. Food Microbiol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"209","DOI":"10.5423\/PPJ.OA.11.2015.0250","article-title":"Inhibition of the Aspergillus flavus Growth and Aflatoxin B1 Contamination on Pistachio Nut by Fengycin and Surfactin-Producing Bacillus subtilis UTBSP1","volume":"32","author":"Farzaneh","year":"2016","journal-title":"Plant Pathol. J."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Awuchi, C.G., Ondari, E.N., Ogbonna, C.U., Upadhyay, A.K., Baran, K., Okpala, C.O.R., Korzeniowska, M., and Guine, R.P.F. (2021). Mycotoxins Affecting Animals, Foods, Humans, and Plants: Types, Occurrence, Toxicities, Action Mechanisms, Prevention, and Detoxification Strategies\u2014A Revisit. Foods, 10.","DOI":"10.3390\/foods10061279"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"125569","DOI":"10.1016\/j.jhazmat.2021.125569","article-title":"Antifungal properties and AFB (1) detoxification activity of a new strain of Lactobacillus plantarum","volume":"414","author":"Zhu","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"ref_42","first-page":"1","article-title":"Efficacy of the antifungal metabolites of Streptomyces philanthi RL-1-178 on aflatoxin degradation with its application to prevent aflatoxigenic fungi in stored maize grains and identification of the bioactive compound","volume":"39","author":"Boukaew","year":"2023","journal-title":"World J. Microbiol. Biotechnol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"109261","DOI":"10.1016\/j.foodcont.2022.109261","article-title":"Biocontrol potential of 1-pentanal emitted from lactic acid bacteria strains against Aspergillus flavus in red pepper (Capsicum annuum L.)","volume":"142","author":"Li","year":"2022","journal-title":"Food Control"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Habschied, K., Krstanovic, V., Zdunic, Z., Babic, J., Mastanjevic, K., and Saric, G.K. (2021). Mycotoxins Biocontrol Methods for Healthier Crops and Stored Products. J. Fungi., 7.","DOI":"10.3390\/jof7050348"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Wu, Q., Li, H., Wang, S., Zhang, Z., Zhang, Z., Jin, T., Hu, X., and Zeng, G. (2022). Differential Expression of Genes Related to Growth and Aflatoxin Synthesis in Aspergillus flavus When Inhibited by Bacillus velezensis Strain B2. Foods, 11.","DOI":"10.3390\/foods11223620"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.foodcont.2017.11.010","article-title":"Unraveling the mode of antifungal action of Bacillus subtilis and Bacillus amyloliquefaciens as potential biocontrol agents against aflatoxigenic Aspergillus parasiticus","volume":"89","author":"Siahmoshteh","year":"2018","journal-title":"Food Control"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10526-020-09996-9","article-title":"Biological control of aflatoxin-producing Aspergillus flavus by volatile organic compound-producing antagonistic yeasts","volume":"65","author":"Jaibangyang","year":"2020","journal-title":"Biocontrol"},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Bertuzzi, T., Leni, G., Bulla, G., and Giorni, P. (2022). Reduction of Mycotoxigenic Fungi Growth and Their Mycotoxin Production by Bacillus subtilis QST 713. Toxins, 14.","DOI":"10.3390\/toxins14110797"},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Shu, X., Wang, Y., Zhou, Q., Li, M., Hu, H., Ma, Y., Chen, X., Ni, J., Zhao, W., and Huang, S. (2018). Biological Degradation of Aflatoxin B-1 by Cell-Free Extracts of Bacillus velezensis DY3108 with Broad PH Stability and Excellent Thermostability. Toxins, 10.","DOI":"10.3390\/toxins10080330"},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Fang, Q.a., Du, M., Chen, J., Liu, T., Zheng, Y., Liao, Z., Zhong, Q., Wang, L., Fang, X., and Wang, J. (2020). Degradation and Detoxification of Aflatoxin B1 by Tea-Derived Aspergillus niger RAF106. Toxins, 12.","DOI":"10.3390\/toxins12120777"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1111\/j.1365-2672.2007.03700.x","article-title":"Isolation of Bacillus spp. from Thai fermented soybean (Thua-nao): Screening for aflatoxin B-1 and ochratoxin A detoxification","volume":"104","author":"Petchkongkaew","year":"2008","journal-title":"J. Appl. Microbiol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"891091","DOI":"10.3389\/fmicb.2022.891091","article-title":"Detoxification of Aflatoxin B1 by a Potential Probiotic Bacillus amyloliquefaciens WF2020","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Microbiol."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Xue, G., Qu, Y., Wu, D., Huang, S., Che, Y., Yu, J., and Song, P. (2023). Biodegradation of Aflatoxin B-1 in the Baijiu Brewing Process by Bacillus cereus. Toxins, 15.","DOI":"10.3390\/toxins15010065"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Yan, Y., Zhang, X., Chen, H., Huang, W., Jiang, H., Wang, C., Xiao, Z., Zhang, Y., and Xu, J. (2022). Isolation and Aflatoxin B1-Degradation Characteristics of a Microbacterium proteolyticum B204 Strain from Bovine Faeces. Toxins, 14.","DOI":"10.3390\/toxins14080525"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Li, S., Xu, X., Zhao, T., Ma, J., Zhao, L., Song, Q., and Sun, W. (2022). Screening of Bacillus velezensis E2 and the Inhibitory Effect of Its Antifungal Substances on Aspergillus flavus. Foods, 11.","DOI":"10.3390\/foods11020140"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"5951","DOI":"10.1007\/s00253-017-8396-0","article-title":"Biological activity of lipopeptides from Bacillus","volume":"101","author":"Zhao","year":"2017","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"112479","DOI":"10.1016\/j.foodres.2023.112479","article-title":"Degradation mechanism of aflatoxin B1 and aflatoxin G1 by salt tolerant Bacillus albus YUN5 isolated from \u2018doenjang\u2019, a traditional Korean food","volume":"165","author":"Kumar","year":"2023","journal-title":"Food Res. Int."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijfoodmicro.2017.05.013","article-title":"Aflatoxin B-1 inhibition in Aspergillus flavus by Aspergillus niger through down-regulating expression of major biosynthetic genes and AFB (1) degradation by atoxigenic A. flavus","volume":"256","author":"Xing","year":"2017","journal-title":"Int. J. Food Microbiol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"5161","DOI":"10.1007\/s00253-014-5632-8","article-title":"The inhibitory effect of Bacillus megaterium on aflatoxin and cyclopiazonic acid biosynthetic pathway gene expression in Aspergillus flavus","volume":"98","author":"Kong","year":"2014","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1099\/mic.0.000070","article-title":"Reduction of aflatoxin production by Aspergillus flavus and Aspergillus parasiticus in interaction with Streptomyces","volume":"161","author":"Verheecke","year":"2015","journal-title":"Microbiol.-Sgm"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"921","DOI":"10.3389\/fmicb.2020.00921","article-title":"Inhibitory Effects of Eurotium cristatum on Growth and Aflatoxin B-1 Biosynthesis in Aspergillus flavus","volume":"11","author":"Zhao","year":"2020","journal-title":"Front. Microbiol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"jkab213","DOI":"10.1093\/g3journal\/jkab213","article-title":"Chromosome assembled and annotated genome sequence of Aspergillus flavus NRRL 3357","volume":"11","author":"Skerker","year":"2021","journal-title":"G3-Genes Genomes Genet."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Gilbert, M.K., Mack, B.M., Lebar, M.D., Chang, P.-K., Gross, S.R., Sweany, R.R., Cary, J.W., and Rajasekaran, K. (2023). Putative Core Transcription Factors Affecting Virulence in Aspergillus flavus during Infection of Maize. J. Fungi, 9.","DOI":"10.3390\/jof9010118"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/jam.14459","article-title":"Antimicrobial Bacillus velezensis HC6: Production of three kinds of lipopeptides and biocontrol potential in maize","volume":"128","author":"Liu","year":"2020","journal-title":"J. Appl. Microbiol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.3389\/fmicb.2018.01049","article-title":"Biocontrol of Aspergillus flavus on Peanut Kernels Using Streptomyces yansingensis 3\u201310","volume":"9","author":"Shakeel","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Dopazo, V., Luz, C., Manes, J., Quiles, J.M., Carbonell, R., Calpe, J., and Meca, G. (2021). Bio-Preservative Potential of Microorganisms Isolated from Red Grape against Food Contaminant Fungi. Toxins, 13.","DOI":"10.3390\/toxins13060412"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/03235408.2016.1160642","article-title":"Biological control of pre-harvest aflatoxin contamination in groundnut (Arachis hypogaea L.) with Bacillus subtilis G1","volume":"49","author":"Shifa","year":"2016","journal-title":"Arch. Phytopathol. Plant Prot."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"109457","DOI":"10.1016\/j.ijfoodmicro.2021.109457","article-title":"Interaction of water activity and temperature on growth, gene expression, and aflatoxin B-1 production in Aspergillus flavus on Indian senna (Cassia angustifolia Vahl.)","volume":"361","author":"Natarajan","year":"2022","journal-title":"Int. J. Food Microbiol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.toxicon.2022.07.006","article-title":"Characterization of Bacillus velezensis E2 with abilities to degrade ochratoxin A and biocontrol against Aspergillus westerdijkiae fc-1","volume":"216","author":"Zhang","year":"2022","journal-title":"Toxicon"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Ju, S., Cao, Z., Wong, C., Liu, Y., Foda, M.F., Zhang, Z., and Li, J. (2019). Isolation and Optimal Fermentation Condition of the Bacillus subtilis Subsp. natto Strain WTC016 for Nattokinase Production. Ferment. -Basel, 5.","DOI":"10.3390\/fermentation5040092"},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"Wang, L., Huang, W., Sha, Y., Yin, H., Liang, Y., Wang, X., Shen, Y., Wu, X., Wu, D., and Wang, J. (2021). Co-Cultivation of Two Bacillus Strains for Improved Cell Growth and Enzyme Production to Enhance the Degradation of Aflatoxin B-1. Toxins, 13.","DOI":"10.3390\/toxins13070435"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"107978","DOI":"10.1016\/j.foodcont.2021.107978","article-title":"Biocontrol capabilities of three Bacillus isolates towards aflatoxin B1 producer A. flavus in vitro and on maize grains","volume":"125","author":"Einloft","year":"2021","journal-title":"Food Control"}],"container-title":["Toxins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6651\/15\/5\/308\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:23:40Z","timestamp":1760124220000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6651\/15\/5\/308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,26]]},"references-count":73,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5]]}},"alternative-id":["toxins15050308"],"URL":"https:\/\/doi.org\/10.3390\/toxins15050308","relation":{},"ISSN":["2072-6651"],"issn-type":[{"value":"2072-6651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,26]]}}}