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Access to antivenom treatment is poorer in indigenous populations compared to other populations. In this study, we report three cases of long-term severe disabilities as a result of Bothrops atrox snakebites in indigenous children, according to the narratives of the parents. The three cases evolved to compartment syndrome, secondary bacterial infection and extensive necrosis. The cases are associated with delayed antivenom treatment due to very fragmented therapeutic itineraries, which are marked by several changes in means of transport along the route. The loss of autonomy at such an early stage of life due to a disability caused by a snakebite, as observed in this study, may deprive children of sensory and social experiences and of learning their future roles in the community. In common to all cases, there was precarious access to rehabilitation services, which are generally centralized in the state capital, and which leads to a prolonged hospitalization of patients with severe snakebite, and distances them from their territory and family and community ties. Prospective studies should be conducted in the Amazon that estimate the burden of disabilities from snakebites in order to formulate public policies for the treatment and rehabilitation of patients through culturally tailored interventions.<\/jats:p>","DOI":"10.3390\/toxins15060352","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T07:00:02Z","timestamp":1684825202000},"page":"352","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Children Growing Up with Severe Disabilities as a Result of Snakebite Envenomations in Indigenous Villages of the Brazilian Amazon: Three Cases and Narratives"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1921-4888","authenticated-orcid":false,"given":"Altair Seabra","family":"de Farias","sequence":"first","affiliation":[{"name":"Escola Superior de Ci\u00eancias da Sa\u00fade, Universidade do Estado do Amazonas, Manaus 69065-001, Brazil"},{"name":"Diretoria de Ensino e Pesquisa, Funda\u00e7\u00e3o de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus 69040-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3225-2723","authenticated-orcid":false,"given":"Joseir Saturnino","family":"Cristino","sequence":"additional","affiliation":[{"name":"Escola Superior de Ci\u00eancias da Sa\u00fade, Universidade do Estado do Amazonas, Manaus 69065-001, Brazil"},{"name":"Diretoria de Ensino e Pesquisa, Funda\u00e7\u00e3o de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus 69040-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Macio","family":"da Costa Ar\u00e9valo","sequence":"additional","affiliation":[{"name":"Distrito Sanit\u00e1rio Especial Ind\u00edgena Alto Rio Solim\u00f5es, Secretaria Especial de Sa\u00fade Ind\u00edgena, Tabatinga 69640-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alceonir","family":"Carneiro Junior","sequence":"additional","affiliation":[{"name":"Distrito Sanit\u00e1rio Especial Ind\u00edgena Manaus, Secretaria Especial de Sa\u00fade Ind\u00edgena, Manaus 69050-010, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoel Rodrigues","family":"Gomes Filho","sequence":"additional","affiliation":[{"name":"Distrito Sanit\u00e1rio Especial Ind\u00edgena Alto Rio Solim\u00f5es, Secretaria Especial de Sa\u00fade Ind\u00edgena, Tabatinga 69640-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sediel Andrade","family":"Ambrosio","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina, Universidade Federal do Amazonas, Manaus 69020-160, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Nickenig Vissoci","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Duke University School of Medicine, Durham, NC 27710, USA"},{"name":"Duke Global Health Institute, Duke University, Durham, NC 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8191-559X","authenticated-orcid":false,"given":"Fan Hui","family":"Wen","sequence":"additional","affiliation":[{"name":"Instituto Butantan, S\u00e3o Paulo 05503-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vin\u00edcius","family":"Azevedo Machado","sequence":"additional","affiliation":[{"name":"Escola Superior de Ci\u00eancias da Sa\u00fade, Universidade do Estado do Amazonas, Manaus 69065-001, Brazil"},{"name":"Diretoria de Ensino e Pesquisa, Funda\u00e7\u00e3o de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus 69040-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Sachett","sequence":"additional","affiliation":[{"name":"Escola Superior de Ci\u00eancias da Sa\u00fade, Universidade do Estado do Amazonas, Manaus 69065-001, Brazil"},{"name":"Diretoria de Ensino e Pesquisa, Funda\u00e7\u00e3o de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus 69040-000, Brazil"},{"name":"Diretoria de Ensino e Pesquisa, Funda\u00e7\u00e3o Alfredo da Matta, Manaus 69065-130, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0848-1940","authenticated-orcid":false,"given":"Wuelton","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Escola Superior de Ci\u00eancias da Sa\u00fade, Universidade do Estado do Amazonas, Manaus 69065-001, Brazil"},{"name":"Diretoria de Ensino e Pesquisa, Funda\u00e7\u00e3o de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus 69040-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,23]]},"reference":[{"key":"ref_1","unstructured":"United Nations Children\u2019s Fund (2022, December 17). 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