{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:34:48Z","timestamp":1791862488384,"version":"4.3.4"},"reference-count":39,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:00Z","timestamp":1701216000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Merz Therapeutics GmbH"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxins"],"abstract":"<jats:p>The objective of this article is to introduce the GO-FAST Tool (developed by the Toxnet group) to clinicians working in the field of neurological rehabilitation, specifically post-stroke spasticity management. The concepts utilized in the Tool and described in this article can be broadly grouped into five topics: the principles of patient-centred goal-setting; an algorithm for setting SMART (specific, measurable, attainable, realistic, and timed) treatment goals; goal-related target muscles and botulinum toxin type A dose determinants; goal attainment follow-up, scoring, and interpretation; and the multimodal approach to spasticity management. The Tool can enhance clinical practice by providing guided assistance with goal-setting and target muscle selection for botulinum toxin type A treatment. It also provides support with the follow-up evaluation of goal attainment and calculation of treatment success. The Tool is designed to be used by clinicians with varying levels of expertise in the field of neurological rehabilitation and post-stroke spasticity management, from those who are new to the field to those with many years of experience. A case study is presented in the Results Section of the article to illustrate the utility of the Tool in setting SMART treatment goals in the management of patients with post-stroke spasticity.<\/jats:p>","DOI":"10.3390\/toxins15120676","type":"journal-article","created":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T03:53:52Z","timestamp":1701230032000},"page":"676","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Selecting Goals and Target Muscles for Botulinum Toxin A Injection Using the Goal Oriented Facilitated Approach to Spasticity Treatment (GO-FAST) Tool"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3428-2312","authenticated-orcid":false,"given":"Jorge","family":"Jacinto","sequence":"first","affiliation":[{"name":"Alcoit\u00e3o Medical Rehabilitation Centre, Rua Conde Bar\u00e3o, 2649-506 Alcabideche, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Balbert","sequence":"additional","affiliation":[{"name":"Department of Adaptive Physical Training, Ural University of Physical Education, Sverdlovsk Regional Hospital for War Veterans, 620014 Yekaterinburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djamel","family":"Bensmail","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Raymond-Poincar\u00e9 Teaching Hospital, APHP, Universit\u00e9 Paris-Saclay, 92380 Garches, France"},{"name":"Unit\u00e9 INSERM 1179, University of Versailles Saint-Quentin-en-Yvelines, 78180 Montigny-Le-Bretonneux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Carda","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurosciences, Service of Neuropsychology and Neurorehabilitation, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Draulans","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Libra Rehabilitation and Audiology, 5022 KE Tilburg, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Deltombe","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Universit\u00e9 Catholique de Louvain, Centre Hospitalier Universitaire de Namur, Godinne Site, Avenue Docteur G Therasse, 5530 Yvoir, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Ketchum","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Medical College of Wisconsin, 9200 W., Milwaukee, WI 53226, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Molteni","sequence":"additional","affiliation":[{"name":"Villa Beretta Rehabilitation Center, Valduce Hospital, 23845 Costa Masnaga, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Reebye","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, BC V5Z 2G9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,29]]},"reference":[{"key":"ref_1","unstructured":"Royal College of Physicians (2018). 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