{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:08:00Z","timestamp":1760058480898,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxins"],"abstract":"<jats:p>A striatal toe is a misalignment of the hallux in dorsal flexion that frequently presents as a symptom of Parkinson\u2019s disease and also atypical Parkinson syndromes. It can negatively impact patients during activities such as walking, putting on socks and shoes, and particularly while wearing shoes. It causes pain and thus induces a loss of quality of life. But, to date, we have few data on the topics of the prevalence, genesis, and therapy of striatal toe. Publications available on botulinum neurotoxin (BoNT) have demonstrated a positive effect in the treatment of striatal toe, although the current study data are also rather limited in this area. Commensurate approval studies have not yet been performed. We will introduce our contemporary data on therapy for striatal toe with BoNT and we will also discuss possible questions open for further study.<\/jats:p>","DOI":"10.3390\/toxins17040168","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T05:29:19Z","timestamp":1743485359000},"page":"168","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Striatal Toe: Too Harmless to Treat?"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8574-3297","authenticated-orcid":false,"given":"Wolfgang H.","family":"Jost","sequence":"first","affiliation":[{"name":"Parkinson-Klinik Ortenau, 77709 Wolfach, Germany"},{"name":"Department of Neurology, University of Saarland, 66421 Homburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3735-8168","authenticated-orcid":false,"given":"Emir","family":"Berberovic","sequence":"additional","affiliation":[{"name":"Parkinson-Klinik Ortenau, 77709 Wolfach, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S1353-8020(02)00010-X","article-title":"The Frequency and Significance of \u2018Striatal Toe\u2019 in Parkinsonism","volume":"9","author":"Winkler","year":"2002","journal-title":"Park. 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[3rd ed.]."}],"container-title":["Toxins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6651\/17\/4\/168\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:07:22Z","timestamp":1760029642000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6651\/17\/4\/168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":21,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4]]}},"alternative-id":["toxins17040168"],"URL":"https:\/\/doi.org\/10.3390\/toxins17040168","relation":{},"ISSN":["2072-6651"],"issn-type":[{"type":"electronic","value":"2072-6651"}],"subject":[],"published":{"date-parts":[[2025,4,1]]}}}