{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T09:07:56Z","timestamp":1789031276080,"version":"build-2803163510"},"reference-count":3,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxins"],"abstract":"<jats:p>The number of patients with chronic kidney disease (CKD) has increased worldwide [...]<\/jats:p>","DOI":"10.3390\/toxins18090387","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T16:30:02Z","timestamp":1788798602000},"page":"387","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Role of Uremic Toxins in Comorbidities of Chronic Kidney Disease"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8279-2966","authenticated-orcid":false,"given":"Suguru","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Division of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, Niigata 951-8510, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Obrero, T., Pend\u00f3n-Ruiz de Mier, M.V., Gordillo-Arnaud, J.E., Moral, M.J.J., Vidal, V., Guerrero, F., Carmona, A., Rodr\u00edguez-Ortiz, M.E., Torralbo, A.I., and Ojeda, R. (2026). Probiotic Supplementation in Chronic Kidney Disease: Outcomes on Uremic Toxins, Inflammation, and Vascular Calcification from Experimental and Clinical Models. Toxins, 18.","DOI":"10.3390\/toxins18010006"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Malaweera, A., Huang, L.L., and McMahon, L.P. (2025). Well-Being, Protein-Bound Toxins, and Dietary Fibre in Patients with Kidney Disease: Have We Been Missing the Obvious?. Toxins, 17.","DOI":"10.3390\/toxins17110548"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Hardjo, M., Wakamatsu, T., Watanabe, K., Yamazaki, S., and Yamamoto, S. (2025). Development and Trends in Uremic Toxin Research: A Comprehensive Bibliometric Analysis. Toxins, 17.","DOI":"10.3390\/toxins17110537"}],"container-title":["Toxins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6651\/18\/9\/387\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T08:18:00Z","timestamp":1789028280000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6651\/18\/9\/387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,7]]},"references-count":3,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["toxins18090387"],"URL":"https:\/\/doi.org\/10.3390\/toxins18090387","relation":{},"ISSN":["2072-6651"],"issn-type":[{"value":"2072-6651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,7]]}}}