{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:45:52Z","timestamp":1791189952360,"version":"4.1.0"},"reference-count":17,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2013,2,18]],"date-time":"2013-02-18T00:00:00Z","timestamp":1361145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxins"],"abstract":"<jats:p>A bradykinin-potentiating peptide (BPP) from Amazon Bothrops atrox venom with m\/z 1384.7386 was identified and characterized by collision induced dissociation (CID) using an ESI-MS\/MS spectra obtained in positive ion mode on a hybrid Qq-oaTOF mass spectrometer, Xevo G2 QTof MS (Waters, Manchester, UK). De novo peptide sequence analysis of the CID fragmentation spectra showed the amino acid sequence ZKWPRPGPEIPP, with a pyroglutamic acid and theoretical monoisotopic m\/z 1384.7378, which is similar to experimental data, showing a mass accuracy of 0.6 ppm. The peptide is homologous to other BPP from Bothrops moojeni and was named as BPP-BAX12.<\/jats:p>","DOI":"10.3390\/toxins5020327","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T11:11:16Z","timestamp":1361272276000},"page":"327-335","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["ESI-MS\/MS Identification of a Bradykinin-Potentiating Peptide from Amazon Bothrops atrox Snake Venom Using a Hybrid  Qq-oaTOF Mass Spectrometer"],"prefix":"10.3390","volume":"5","author":[{"given":"Antonio","family":"Coutinho-Neto","sequence":"first","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cle\u00f3patra","family":"Caldeira","sequence":"additional","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Souza","sequence":"additional","affiliation":[{"name":"MS Applications Development Laboratory, Waters Corporation, Alphaville, SP 06455-020, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayena","family":"Zaqueo","sequence":"additional","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anderson","family":"Kayano","sequence":"additional","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Silva","sequence":"additional","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Zuliani","sequence":"additional","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"},{"name":"Medicine Department, Federal University of Rond\u00f4nia, Porto Velho, RO 76801-059, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreimar","family":"Soares","sequence":"additional","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"St\u00e1beli","sequence":"additional","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"},{"name":"Medicine Department, Federal University of Rond\u00f4nia, Porto Velho, RO 76801-059, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Calderon","sequence":"additional","affiliation":[{"name":"Center of Biomolecules Study Applied to Health, Fiocruz Rond\u00f4nia, Oswaldo Cruz Foundation, Porto Velho, RO 76820-245, Brazil"},{"name":"Medicine Department, Federal University of Rond\u00f4nia, Porto Velho, RO 76801-059, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2013,2,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1002\/rcm.1973","article-title":"Fast analysis of low molecular mass compounds present in snake venom: Identification of ten new pyroglutamate-containing peptides","volume":"19","author":"Wermelinger","year":"2005","journal-title":"Rapid Commun. 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