{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:26:05Z","timestamp":1760059565321,"version":"build-2065373602"},"reference-count":80,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T00:00:00Z","timestamp":1750464000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>Lagochilascariasis is a neglected zoonotic helminthiasis, caused by Lagochilascaris minor, characterized by a complex and not well understood transmission cycle. This parasitic disease is endemic to Latin America, particularly Brazil, and is associated with rural and forested areas, where humans may serve as accidental hosts. The southeastern region of Par\u00e1 state reports the highest number of cases, highlighting its epidemiological significance. Wildlife species, especially carnivores and rodents, play crucial roles as definitive and intermediate hosts, respectively. Although lagochilascariasis can lead to severe clinical manifestations, including chronic soft tissue infections and potential central nervous system involvement, it is likely underdiagnosed due to its similarity to fungal and bacterial diseases. The anthropization of the Amazon Biome, through deforestation and habitat fragmentation, coupled with increased human\u2013wildlife interactions, may be influencing the epidemiology of this parasitosis. This review aims to summarize current knowledge of L. minor transmission routes, the role of wildlife in maintaining its cycle, and the impact of environmental changes on disease patterns. Such insights are vital for One Health strategies, which integrate human, animal, and environmental health approaches to mitigate the disease burden.<\/jats:p>","DOI":"10.3390\/tropicalmed10070177","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T03:39:26Z","timestamp":1750649966000},"page":"177","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lagochilascariasis: A Neglected Zoonosis in the Brazilian Amazon Biome and the Role of Wildlife in Its Epidemiological Chain Amidst Anthropization"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7711-6437","authenticated-orcid":false,"given":"Felipe Masiero","family":"Salvarani","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Medicina Veterin\u00e1ria Preventiva, Instituto de Medicina Veterin\u00e1ria, Universidade Federal do Par\u00e1, Castanhal 68740-970, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6462-2058","authenticated-orcid":false,"given":"Karoline Petrini Pinheiro","family":"da Cruz","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Medicina Veterin\u00e1ria Preventiva, Instituto de Medicina Veterin\u00e1ria, Universidade Federal do Par\u00e1, Castanhal 68740-970, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1345-5413","authenticated-orcid":false,"given":"Flavio Roberto Chaves","family":"da Silva","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Virologia Geral e Parasitologia, Centro de Ci\u00eancias Biol\u00f3gicas e da Natureza, Universidade Federal do Acre, Rio Branco 69920-900, AC, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0795-3934","authenticated-orcid":false,"given":"C\u00edntia","family":"Daudt","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Virologia Geral e Parasitologia, Centro de Ci\u00eancias Biol\u00f3gicas e da Natureza, Universidade Federal do Acre, Rio Branco 69920-900, AC, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1590\/S0036-46651992000400003","article-title":"Experimental Life Cycle of Lagochilascaris minor Leiper, 1909","volume":"34","author":"Campos","year":"1992","journal-title":"Rev. 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