{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:42:42Z","timestamp":1760060562068,"version":"build-2065373602"},"reference-count":82,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Vicerector\u00eda de Investigaci\u00f3n y Doctorados, Universidad San Sebasti\u00e1n","award":["VRID-FAPPE 22-04"],"award-info":[{"award-number":["VRID-FAPPE 22-04"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TropicalMed"],"abstract":"<jats:p>At a veterinary hospital in southern Chile, we conducted an epidemiological study involving domestic dogs, cats, and horses to determine the seropositivity for pathogenic Leptospira spp., identify the infecting serogroups, measure antibody titers, and characterize seropositive animals by sex and age. None of the sampled animals showed clinical signs of leptospirosis. The microscopic agglutination test, using a panel of eight serogroups, was used for diagnosis. The seropositivity was 36.5% (95% confidence interval [CI] = 24.5\u201348.4) in dogs, 12.9% (95% CI = 2.6\u201323.1) in cats, and 45.2% (95% CI = 30.1\u201360.2) in horses. Serological reactions were detected for the Tarassovi and Canicola serogroups in dogs, Sejroe, Canicola, Icterohaemorrhagiae, and Grippotyphosa in horses, and Tarassovi in cats. The most frequent antibody titers were 1:200 and 1:400 in dogs, 1:400 in cats, and 1:800 in horses. The distribution of seropositivity varied by sex and age across different animal species. The seropositivity for pathogenic Leptospira in dogs, cats, and horses attending a veterinary hospital underscores the role of domestic animals as sentinels for zoonotic diseases. This finding has implications for epidemiological surveillance systems in increasing awareness of seropositivity and establishing specific prevention measures to mitigate the risk of leptospirosis transmission.<\/jats:p>","DOI":"10.3390\/tropicalmed10090253","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T08:04:15Z","timestamp":1756886655000},"page":"253","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seropositivity for Pathogenic Leptospira in Dogs, Cats, and Horses at a Teaching Veterinary Hospital in Southern Chile"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1602-9866","authenticated-orcid":false,"given":"Luc\u00eda","family":"Az\u00f3car-Aedo","sequence":"first","affiliation":[{"name":"Facultad de Medicina Veterinaria, Escuela de Medicina Veterinaria, Universidad San Sebasti\u00e1n, Sede de la Patagonia, Puerto Montt 5480000, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Meniconi","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria, Escuela de Medicina Veterinaria, Universidad San Sebasti\u00e1n, Sede de la Patagonia, Puerto Montt 5480000, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Pino-Olgu\u00edn","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria, Escuela de Medicina Veterinaria, Universidad San Sebasti\u00e1n, Sede de la Patagonia, Puerto Montt 5480000, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8148-2571","authenticated-orcid":false,"given":"Mar\u00eda","family":"Gallardo","sequence":"additional","affiliation":[{"name":"Facultad de Medicina y Ciencias de la Salud, Escuela de Medicina Veterinaria, Universidad Mayor, Campus Huechuraba, Santiago 8580000, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,3]]},"reference":[{"key":"ref_1","first-page":"123","article-title":"Leptospira spp. y leptospirosis humana","volume":"32","author":"Falconar","year":"2016","journal-title":"Salud Uninorte"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.actatropica.2017.12.010","article-title":"Major epidemiological factors associated with leptospirosis in Malaysia","volume":"178","author":"Garba","year":"2018","journal-title":"Acta Trop."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"100518","DOI":"10.1016\/j.nmni.2019.100518","article-title":"Leptospirosis in French Polynesia: 11 years of surveillance data, 2007\u20132017","volume":"29","author":"Bouscaren","year":"2019","journal-title":"New Microbes New Infect."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"129","DOI":"10.6001\/biologija.v68i2.4733","article-title":"Leptospirosis: Classification, epidemiology, and methods of detection. 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